Lymphadenopathies May Be Presenting Sign Of Disease Exacerbation In Patients With Systemic Lupus Erythematosus

Year 2016, Volume: 1 Issue: 3, 126 - 129, 01.10.2017

Esin Beyan , Gülçin Güler Şimşek

Abstract

Lymphadenopathy is frequently seen in the course of systemic lupus erythematosus (SLE). On the other hand,

infections, malignant and other immunological disorders are the reasons of lymphadenopathies. Therefore, differential diagnosis is very important. It is mentioned that SLE patients with lymphadenopathy has been found to have higher disease activity. But, lymphadenopathy as the first clinical manifestation of the disease activation is very rare. Herein, a SLE case that has lymphadenopathy as a presentation sign of active disease was reported. 

Keywords

Lymphadenopathy, recurrence, systemic lupus erythematosus

Lenfadenopatiler Sistemik Lupus Eritematozuslu Hastalarda Hastalık Alevlenmesinin Habercisi Olabilir

Abstract

Lenfadenopati, sistemik lupus eritamatozus (SLE) seyrinde sık görülen bir bulgudur. Öte yandan enfeksiyonlar, malign hastalıklar ve diğer immünolojik hastalıklar da SLE seyrinde ortaya çıkıp lenfadenopatiye neden olabilirler. Bu yüzden ayırıcı tanı büyük önem taşır. Lenfadenopati saptanan

SLE’li hastalarda hastalık aktivitesinin daha yüksek olduğu belirtilmektedir. Ancak aktivasyonun ilk bulgusu olması nadirdir. Bu makalede hastalık aktivasyonunun başlangıç bulgusu lenfadenopati olan bir SLE olgusu sunulmuştur.

Keywords

Lenfadenopati, nüks, sistemik lupus eritematozu

References

• 1. Calgüneri M, Oztürk MA, Ozbalkan Z, et al. Frequency of lymphadenopathy in rheumatoid arthritis and systemic lupus erythematosus. J Int Med Res 2003; 31: 345-9.
• 2. Shapira Y, Weinberger A, Wysenbeek AJ. Lymphadenopathy in systemic lupus erythematosus. Prevalence and relation to disease manifestations. Clin Rheumatol 1996; 15: 335-8.
• 3. Melikoglu MA, Melikoglu M. The clinical importance of lymphadenopathy in systemic lupus erythematosus. Acta Reumatol Port 2008; 33: 402-6.
• 4. Bukiej A, Undas A, Pituch-Noworolska A, Chmielewska A, Dyczek A, Musiał J. Association of peripheral lymphadenopathy with anti-Ro and anti-La antibodies in a family with systemic lupus erythematosus. Scand J Rheumatol 2003; 32: 52-4.
• 5. Kitsanou M, Andreopoulou E, Bai MK, Elisaf M, Drosos AA. Extensive lymphadenopathy as the first clinical manifestation in systemic lupus erythematosus. Lupus 2000; 9: 140-3.
• 6. Afzal W, Arab T, Ullah T, Teller K, Doshi KJ. Generalized Lymphadenopathy as Presenting Feature of Systemic Lupus Erythematosus: Case Report and Review of the Literature. J Clin Med Res 2016; 8: 819-823.
• 7. Santana A, Lessa B, Galrão L, Lima I, Santiago M. Kikuchi- Fujimoto’s disease associated with systemic lupus erythematosus: case report and review of the literature. Clin Rheumatol 2005; 24: 60-3.