Anestezi Seçiminin Mesane Kanseri Nedeniyle Cerrahiye Giden Hastalarda Sağkalım Üzerine Etkisi: Retrospektif Değerlendirme

Year 2020, , 1 - 7, 08.04.2020

Gülseren Yılmaz

https://doi.org/10.5505/abantmedj.2020.05902

Abstract

GİRİŞ ve AMAÇ: Rejyonel anestezinin mesane kanseri bulunan hastalarda sağkalım üzerindeki rolünü incelemiş olan çalışma sayısı sınırlıdır. Bu geriye dönük çalışma rejyonel ve genel anestezinin mesane kanseri nedeniyle cerrahi geçiren hastalarda sağkalım üzerine etkilerini karşılaştırmayı amaçlamıştır.

YÖNTEM ve GEREÇLER: Mesane kanseri nedeniyle cerrahi geçiren toplam 181 hasta (ortalama yaş 62±11 yıl, % 82 erkek) bu geriye dönük çalışmaya dahil edilmişlerdir. Hastalara ilişkin tüm veriler hasta dosyalarından alınmıştır. Hastalar rejyonel anestezi (RA grubu, n=120) ve genel anestezi (GA grubu, n=61) olmak üzere iki gruba ayrılmışlardır.

BULGULAR: Rejyonel anestezi uygulanan hastalarda 3 yılllık sağkalım genel anestezi grubuna göre anlamlı olarak yüksekti ( % 96.6’ya karşı % 86.8, p=0.012). Lojistik regresyon analizi postoperatif enfeksiyon gelişiminin (OO: 0.221, % 95 GA: 0.065-0.754, p=0.016) ve rejyonel anestezi uygulamasının (OO: 4.275, % 95 GA: 1.230-14.852, p=0.020) 3 yıllık sağkalım için anlamlı belirleyiciler olduklarını göstermiştir.

TARTIŞMA ve SONUÇ: Bu çalışmanın bulguları mesane kanseri nedeniyle cerrahiye giden hastalarda rejyonel anestezinin genel anesteziye göre daha iyi 3 yıllık sağkalım sağladığını göstermiştir. Postoperatif enfeksiyon gelişimi ve anestezi tekniği sağkalımın önemli belirleyicileri olarak tespit edilmişlerdir.

Keywords

Mesane kanseri, rejyonel anestezi

The effect of anesthesia choice on survival in patients undergoing surgery for bladder cancer: a retrospective analysis

Abstract

INTRODUCTION: Data investigating the role of regional anesthesia on survival in bladder cancer is lacking. This retrospective study aimed to compare the impact of regional anesthesia and general anesthesia on survival in patients who underwent surgery for bladder cancer.

METHODS: A total of 181 patients (mean age 62±11 years, 82 % male) who underwent surgery for bladder cancer were enrolled in this retrospective study. All data were collected from patient case charts. Patients were divided into two study groups according to the type of anesthesia used: Regional anesthesia group (RA Group) (n=120) and general anesthesia group (GA Group) (n=61).

RESULTS: Three-years survival following surgery was significantly higher in patients receiving regional anesthesia compared to those receiving general anesthesia (96.6% vs. 86.8%, p=0.012). Logistic regression analyses showed that postoperative infection (OR: 0.221, 95 % CI: 0.065-0.754, p=0.016) and implementation of regional anesthesia (OR: 4.275, 95 % CI: 1.230-14.852, p=0.020) were predictive for 3-years survival.

DISCUSSION AND CONCLUSION: Findings of the present study demonstrate that regional anesthesia provides better 3-year survival compared to general anesthesia in patients undergoing surgery for bladder cancer. Postoperative infections and anesthesia technique are the predictors of survival in these patients.

Keywords

Bladder cancer, regional anesthesia

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