Ovarian Hyperstimulation Syndrome in A Spontaneous Pregnancy After Cessation of A Long-Term Combined Oral Contraceptive Use: A Case Report

Year 2020, , 45 - 48, 08.04.2020

Ayşe Nur Aksoy , Ebru Bulut Erdem Elcin Telli

https://doi.org/10.5505/abantmedj.2020.68926

Abstract

Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of ovulation induction or controlled ovarian hyperstimulation. The OHSS frequently occurs due to the administration of human chorionic gonadotropin (hCG) in controlled ovarian hyperstimulation cycles. However, OHSS has been reported rarely in normal spontaneous pregnancy cases. In this paper, a case of mild OHSS at 10 weeks 5 days of gestation in a woman with singleton gestation, who conceived naturally after cessation of a long-term combined oral contraceptive use was reported. Patients using long-term oral contraceptive should be informed about the symptoms of OHSS for early diagnosis. Early diagnosis and appropriate supportive therapy are essential to avoid the potentially life-threatening complications of OHSS.

Keywords

ovarian hyperstimulation syndrome, combined oral contraceptive, pregnancy

Uzun süreli kombine oral kontraseptif kullanımının bırakılmasından sonra oluşan spontan bir gebelikte ovarian hiperstimülasyon sendromu: Bir olgu sunumu

Abstract

Ovarian hiperstimülasyon sendromu (OHSS), ovulasyon indüksiyonunun veya kontrollü ovarian hiperstimülasyonun iatrojenik bir komplikasyonudur. Ovarian hiperstimülasyon sendromu, kontrollü ovarian hiperstimülasyon sikluslarında insan koryonik gonadotropin (hCG) uygulamasından dolayı sıklıkla meydana gelir. Ancak, normal spontan gebelik vakalarında OHSS nadir olarak bildirilmiştir. Bu yazıda, uzun süreli kombine oral kontraseptif kullanımının kesilmesinden sonra spontan gebe kalan, tekil gebeliği olan bir kadında, 10 hafta 5 günlük gebelik haftasında orta şiddette OHSS vakası bildirilmiştir. Uzun süreli oral kontraseptif kullanan hastalar erken tanı için OHSS semptomları hakkında bilgilendirilmelidir. Erken tanı ve uygun destek tedavisi, OHSS'nin yaşamı tehdit edici komplikasyonlarından kaçınmak için esastır.

Keywords

ovarian hiperstimülasyon sendromu, kombine oral kontraseptif, gebelik

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