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Ondokuz Hafta Gebelikte Misoprostol Kullanımına Bağlı Uterus Rüptürü

Year 2017, , 29 - 31, 01.01.2017
https://doi.org/10.5505/abantmedj.2017.24865

Abstract

Amaç: Sentetik prostaglandin E1 analoğu olan misoprostol, gastrik ülser tedavisi için onay almış olmasına rağmen kadın hastalıkları ve doğum pratiğinde birinci ve ikinci trimester gebelikleri sonlandırmada, term gebeliklerde doğum indüksiyonunda ve postpartum kanamaların yönetiminde sık olarak kullanılmaktadır. Misoprostolün güvenilirliği, yaygın kullanılması ve tedavide etkin olmasına rağmen geçirilmiş sezaryen öyküsü olan hastalarda artan uterus rüptürü nedeniyle sorgulanmaktadır. Materyal ve Metod: Olgu sunumunda, ölü fetus tanısı ile gebelik terninasyonu planlanan 19 haftalık gebeliği bulunan, geçirilmiş alt segment sezaryen ve myomektomi öyküsü olan hastada misoprostol kullanımı sonrası ortaya çıkan uterus rüptürünü sunacağız.Bulgular: Misoprostol kullanımı sonrası hastada uterus rüptürü meydana gelmiş, hasta acil olarak ameliyata alınıp kanama durdurulmuş ve rüptür hattı onarılmıştır Sonuç: Geçirilmiş uterus cerrahisi öyküsü olan gebelerde misoprostol kullanımı ile uterus rüptürü riski artmakta olup Misoprostol, daha dikkatli kullanılmalıdır.

References

  • Nayki U, Taner CE, Mizrak T, Nayki C, Derin G. Uterine rupture during second trimester abortion with misoprostol. Fetal Diagn Ther. 2005; 20 (5): 469-71.
  • Nucatola D, Roth N, Saulsberry V, Gatter M. Serious adverse events associated with the use of misoprostol alone for cervical preparation prior to early second trimester surgical abortion (12-16 weeks). Contraception. 2008; 78 (3):245-8.
  • Berghella V, Airoldi J, O'Neill AM, Einhorn K, Hoffman M. Misoprostol for second trimester pregnancy termination in women with prior caesarean: a systematic review. BJOG. 2009; 116 (9): 1151
  • Fawzy M, Abdel-Hady el-S. Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries. Int J Gynaecol Obstet. 2010; 110 (1): 50-2.
  • Küçükgöz Güleç U, Urunsak IF, Eser E, Guzel AB, Ozgunen FT, Evruke IC, Buyukkurt S. Misoprostol for midtrimester termination of pregnancy in women with one or more prior cesarean deliveries. Int J Gynaecol Obstet. 2013; 120 (1): 85-7.
  • Cuellar Torriente M. Silent uterine rupture with the use of misoprostol for second trimester termination of pregnancy: a case report. Obstet Gynecol Int. 2011; 2011: 584652.
  • Lin C, Raynor BD. Risk of uterine rupture in labor induction of patients with prior cesarean section: an inner city hospital experience. Am J Obstet Gynecol. 2004; 190 (5):1476-8.
  • Majoko F, Magwali T, Zwizwai M. Uterine rupture associated with use of misoprostol for induction of labor. Int J Gynaecol Obstet. 2002; 76 (1): 77-8.

Uterine Rupture with Misoprostol at 19 Week of Gestation

Year 2017, , 29 - 31, 01.01.2017
https://doi.org/10.5505/abantmedj.2017.24865

Abstract

Objective: Misoprostol is a synthetic prostaglandin E1 analogue that has been used commonly at obstetric practice even though received approval as an oral agent for the preventing of gastric ulcers. Its’ widely used at obstetric practice such as first and second trimester pregnancy termination, labor induction at term and management of postpartum hemorrhage. Even though its’ efficacy and widespread use, its safety is questioned in women with prior caesarean birth by the reason of increasing number of uterine rupture. Materials and method: We report a second trimester pregnant women with demised fetus with the history of myomectomy and prior low segment caesarean section who had uterine rupture after misoprostol administration.Results: Because of uterine rupture, we performed emergency laparotomy and repaired the rupture line Conclusion: Misoprostol has to be used more careful at patients with prior uterine surgery do to the increased uterine rupture risk.

References

  • Nayki U, Taner CE, Mizrak T, Nayki C, Derin G. Uterine rupture during second trimester abortion with misoprostol. Fetal Diagn Ther. 2005; 20 (5): 469-71.
  • Nucatola D, Roth N, Saulsberry V, Gatter M. Serious adverse events associated with the use of misoprostol alone for cervical preparation prior to early second trimester surgical abortion (12-16 weeks). Contraception. 2008; 78 (3):245-8.
  • Berghella V, Airoldi J, O'Neill AM, Einhorn K, Hoffman M. Misoprostol for second trimester pregnancy termination in women with prior caesarean: a systematic review. BJOG. 2009; 116 (9): 1151
  • Fawzy M, Abdel-Hady el-S. Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries. Int J Gynaecol Obstet. 2010; 110 (1): 50-2.
  • Küçükgöz Güleç U, Urunsak IF, Eser E, Guzel AB, Ozgunen FT, Evruke IC, Buyukkurt S. Misoprostol for midtrimester termination of pregnancy in women with one or more prior cesarean deliveries. Int J Gynaecol Obstet. 2013; 120 (1): 85-7.
  • Cuellar Torriente M. Silent uterine rupture with the use of misoprostol for second trimester termination of pregnancy: a case report. Obstet Gynecol Int. 2011; 2011: 584652.
  • Lin C, Raynor BD. Risk of uterine rupture in labor induction of patients with prior cesarean section: an inner city hospital experience. Am J Obstet Gynecol. 2004; 190 (5):1476-8.
  • Majoko F, Magwali T, Zwizwai M. Uterine rupture associated with use of misoprostol for induction of labor. Int J Gynaecol Obstet. 2002; 76 (1): 77-8.
There are 8 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Nuri Peker This is me

Ahmet Demir This is me

Publication Date January 1, 2017
Published in Issue Year 2017

Cite

APA Peker, N., & Demir, A. (2017). Uterine Rupture with Misoprostol at 19 Week of Gestation. Abant Medical Journal, 6(1), 29-31. https://doi.org/10.5505/abantmedj.2017.24865
AMA Peker N, Demir A. Uterine Rupture with Misoprostol at 19 Week of Gestation. Abant Med J. January 2017;6(1):29-31. doi:10.5505/abantmedj.2017.24865
Chicago Peker, Nuri, and Ahmet Demir. “Uterine Rupture With Misoprostol at 19 Week of Gestation”. Abant Medical Journal 6, no. 1 (January 2017): 29-31. https://doi.org/10.5505/abantmedj.2017.24865.
EndNote Peker N, Demir A (January 1, 2017) Uterine Rupture with Misoprostol at 19 Week of Gestation. Abant Medical Journal 6 1 29–31.
IEEE N. Peker and A. Demir, “Uterine Rupture with Misoprostol at 19 Week of Gestation”, Abant Med J, vol. 6, no. 1, pp. 29–31, 2017, doi: 10.5505/abantmedj.2017.24865.
ISNAD Peker, Nuri - Demir, Ahmet. “Uterine Rupture With Misoprostol at 19 Week of Gestation”. Abant Medical Journal 6/1 (January 2017), 29-31. https://doi.org/10.5505/abantmedj.2017.24865.
JAMA Peker N, Demir A. Uterine Rupture with Misoprostol at 19 Week of Gestation. Abant Med J. 2017;6:29–31.
MLA Peker, Nuri and Ahmet Demir. “Uterine Rupture With Misoprostol at 19 Week of Gestation”. Abant Medical Journal, vol. 6, no. 1, 2017, pp. 29-31, doi:10.5505/abantmedj.2017.24865.
Vancouver Peker N, Demir A. Uterine Rupture with Misoprostol at 19 Week of Gestation. Abant Med J. 2017;6(1):29-31.