Presenting symptoms of pediatric patients with celiac disease

Year 2015, , 146 - 150, 01.05.2015

İdil Akay Hacı Pınar Kuyum Sevim Çakar İshak Işık Nur Arslan

https://doi.org/10.5505/abantmedj.2015.96977

Abstract

OBJECTIVE: By the advancement in serological tests, non-typically presented celiac patients could be diagnosed easily. Aim of this study was to investigate the presenting symptoms of newly diagnosed celiac patients. METHODS: Records of newly diagnosed 60 celiac patients were investigated for the presenting symptoms and antropometric measurements retrospectively. Celiac disease was diagnosed by serological tests and detection of villus atrophy in intestinal biopsy. Patients were devided into three groups according to their presenting symptoms and findings: Patients presented with gastrointestinal GIS symptoms, other than GIS symptoms and asymptomatic patients. RESULTS: Mean age of patients was 8.6 ± 4.7 years. 11 patients 18.3% presented with GIS symptoms diarrhea, constipation, etc. ; 35 58,3% of them presented with non-GIS related symptoms growth retardation, anemia, muscle weakness etc. and 14 23,4 % of them had no symptoms. Asymptomatic patients had been diagnosed by screening celiac disease. Three patients 5% had obesity at admission. CONCLUSION: In this study, it was shown that most of the celiac patients presented with non-GIS related symtoms or even without any symptom. This can be caused by both widely using serological tests all over the world and also by investigating the patients who had atypical symptoms for celiac disease in recent years, carefully.

Keywords

Presenting symptoms, celiac disease, child

Çölyak hastalığı tanısı konulan çocukların başvuru bulguları

Abstract

AMAÇ: Serolojik tanı testlerinin gelişmesi ile çölyak hastalığının tipik olmayan bulgularını taşıyan hastalara da tanı konulması kolaylaşmıştır. Bu çalışmanın amacı yeni çölyak hastalığı tanısı konulan hastalarda başvuru bulgularının araştırılmasıdır.YÖNTEMLER: Çölyak hastalığı tanısı alan 60 hastanın başvuru yakınmaları ve antropometrik verileri retrospektif olarak araştırıldı. Çölyak hastalığı tanısı serolojik değerlendirme ve ince bağırsak biyopsisinde villöz atrofi saptanması ile konuldu. Hastalar başvuru yakınmaları ve bulgularına göre gastrointestinal sistem GİS bulgularıyla başvuranlar, GİS dışı bulgularla başvuranlar ve yakınması olmayan hastalar olmak üzere üç gruba ayrıldı. BULGULAR: Hastaların başvuru sırasında ortalama yaşı 8.6 ± 4.7 yıl idi. 11 hasta %18.3 GİS bulgularıyla ishal, kabızlık , 35 hasta %58.3 GİS dışı bulgularla büyüme geriliği, kas güçsüzlüğü, anemi başvurmuştu. 14 hastanın ise %23.4 başvuru sırasında yakınması yoktu, tarama amacıyla serolojik tetkikler istenmişti ve tanı konulmuştu. 3 hastada %5 tanı sırasında obesite saptandı. SONUÇ: Çalışmamız çölyak hastalığı tanısı alan hastaların çoğunluğunun klasik olmayan gastrointestinal sistem dışı bulgularla başvurduğunu veya taramalar sırasında saptandığını göstermektedir. Bu durum, tüm dünyada hastalığın klasik olmayan GİS dışı bulgularının da dikkatle değerlendirilmesi ve serolojik tetkiklerin bu hastalarda istenmesi ile tanı almalarından kaynaklanmaktadır.

Keywords

Başvuru bulguları, çölyak hastalığı, çocuk

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