Tedavi Almayan Obsesif Kompulsif Bozukluk Hastalarında Nötrofil / Lenfosit ve Platelet / Lenfosit Oranlarının Değerlendirilmesi

Year 2021, Volume: 10 Issue: 3, 360 - 368, 21.12.2021

İsmet Esra Çiçek , Medine Gıynaş Ayhan , Seda Kırcı Ercan , Erdinç Çiçek Ülkü Beşiktepe Ayan İbrahim Eren

https://doi.org/10.47493/abantmedj.883982

Cited By: 1

Abstract

Amaç: Çalışmada tedavisiz obsesif kompulsif bozukluk (OKB) hastalarında nötrofil/lenfosit oranı (NLR) ve platelet/ lenfosit oranının (PLR), sağlıklı kontroller ile karşılaştırılması amaçlanmıştır. Ayrıca içgörü düzeyleri ile NLR ve PLR arasındaki ilişki değerlendirilmiştir.
Gereç ve Yöntemler: Çalışmaya tedavi almayan ardışık 56 OKB hastası ve hasta grubu ile benzer sosyodemografik özelliklere sahip 56 sağlıklı birey, kontrol grubu olarak belirlendi. Hastalar ve kontrol grubu psikiyatrik bozukluklar ve hemogram parametreleri açısından değerlendirildi. Obsesif kompulsif belirtilerin şiddeti ve içgörü düzeyi Yale-Brown Obsesif Kompulsif Ölçeği ile değerlendirildi.
Bulgular: Ortalama OKB başlangıç yaşı 19.54±3.98 yıl, ortalama hastalık süresi 3.90±2.77 yıl olarak bulundu. OKB hastalarında ortalama NLR ve PLR düzeyleri sağlıklı kontrollere göre anlamlı derecede yüksekti. İçgörüsü olmayan veya zayıf olan OKB hastalarında PLR düzeyleri daha yüksek saptandı
Sonuç: Bulgularımıza göre OKB hastalarında NLR, PLR değerlerinin yüksekliği ve içgörüsü yetersiz/olmayan hastalarda PLR yüksekliği etyolojide inflamatuar süreçlerin rolü olabileceğini göstermektedir

Keywords

obsesif kompulsif bozukluk, Nötrofil / lenfosit oranı, Platelet / lenfosit oranı, İnflamasyon

Supporting Institution

Yok

Evaluation of Neutrophil / Lymphocyte and Platelet / Lymphocyte Ratios in Patients with Untreated Obsessive Compulsive Disorder

Abstract

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