Intracranial germinomas are rare cancers that primarily affect
pediatric age group patients makingthem rarer still in adults. This
report presents a case of a primary intracranial germinoma arising in
the pineal region of a 24 year old male. The patient presented with a
history of weight loss and progressive vision loss secondary to
obstructive hydrocephalus. MRI demonstrated a large enhancing mass
lesion in the region of the pineal gland with radiological features
suggestive of a germinoma. Immunohistochemical stains confirmed
the histological diagnosis, with positive staining for C-Kit, OCT4 and
PLAP. In summary, this case report highlights that the diagnosis of
pineal gland germinoma present in a young male is made by
immunohistochemistry and detailed physical examination
Primary Language | English |
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Subjects | Traditional, Complementary and Integrative Medicine (Other) |
Journal Section | Case Report |
Authors | |
Publication Date | January 30, 2023 |
Published in Issue | Year 2023 |