Research Article
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Year 2024, , 96 - 101, 27.09.2024
https://doi.org/10.5505/achmedj.2024.87587

Abstract

References

  • 1. Nisolle M, Alvarez ML, Colombo M, Foidart JM. [Pathogenesis of endometriosis]. Gynecol Obstet Fertil. 2007; 35: 898-903.
  • 2. Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ. Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol. 2004; 160: 784-796.
  • 3. Prescott J, Farland LV, Tobias DK et al. A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod. 2016; 31: 1475-1482.
  • 4. Nominato NS, Prates LF, Lauar I, Morais J, Maia L, Geber S. Caesarean section greatly increases risk of scar endometriosis. Eur J Obstet Gynecol Reprod Biol. 2010; 152: 83-85.
  • 5. Uzuncakmak C, Guldas A, Ozcam H, Dinç K. Scar endometriosis: a case report of this uncommon entity and review of the literature. Case Rep Obstet Gynecol. 2013; 2013: 386783.
  • 6. Buscemi S, Maiorana A, Fazzotta S et al. Scar endometriosis: not a rare cause for a painful scar. Clin Ter. 2021; 172: 129-133.
  • 7. Horton JD, Dezee KJ, Ahnfeldt EP, Wagner M. Abdominal wall endometriosis: a surgeon’s perspective and review of 445 cases. Am J Surg. 2008; 196: 207-212.
  • 8. Zhang P, Sun Y, Zhang C et al. Cesarean scar endometriosis: presentation of 198 cases and literature review. BMC Womens Health. 2019; 19: 14.
  • 9. Hirata T, Koga K, Osuga Y. Extra-pelvic endometriosis: A review.Reprod Med Biol. 2020; 19: 323-333.
  • 10. Youssef AT. The ultrasound of subcutaneous extrapelvic endometriosis. J Ultrason. 2020; 20: e176-e180.
  • 11. Pas K, Joanna SM, Renata R, Skręt A, Barnaś E. Prospective study concerning 71 cases of caesarean scar endometriosis (CSE). J Obstet Gynaecol. 2017; 37: 775-778.
  • 12. Benedetto C, Cacozza D, de Sousa Costa D et al. Abdominal wall endometriosis: Report of 83 cases. Int J Gynaecol Obstet. 2022; 159: 530-536.
  • 13. Durairaj A, Sivamani H, Panneerselvam M. Surgical Scar Endometriosis: An Emerging Enigma. Cureus. 2023; 15: e35089.
  • 14. Seckin KD, Kadirogullari P. Is dienogest a convenient treatment option for cesarean scar endometriosis or should it be treated surgically? Eur J Obstet Gynecol Reprod Biol. 2023; 282: 110-115.
  • 15. Dwivedi U, Shukla S, Anand N, Parashar C, Husain N. Scar Endometriosis: Cytological Diagnosis. JNMA J Nepal Med Assoc. 2018; 56: 550-552.
  • 16. Szubert M, Nowak-Gluck A, Domanska-Senderowska D et al. miR 31-3p Has the Highest Expression in Cesarean Scar Endometriosis. Int J Mol Sci. 2022; 23.
  • 17. Carsote M, Terzea DC, Valea A, Gheorghisan-Galateanu AA. Abdominal wall endometriosis (a narrative review). Int J Med Sci. 2020; 17: 536-542.
  • 18. Knorren ER, de Ridder LA, Nijholt IM et al. Effectiveness and complication rates of high intensity focused ultrasound treatment for abdominal wall endometriosis: A systematic review. Eur J Obstet Gynecol Reprod Biol. 2024 Mar 26;297:15-23.
  • 19. Marras S, Pluchino N, Petignat P et al. Abdominal wall endometriosis: An 11-year retrospective observational cohort study. Eur J Obstet Gynecol Reprod Biol X. 2019; 4: 100096.
  • 20. Mihailovici A, Rottenstreich M, Kovel S, Wassermann I, Smorgick N, Vaknin Z. Endometriosis-associated malignant transformation in abdominal surgical scar: A PRISMA-compliant systematic review. Medicine (Baltimore). 2017; 96: e9136.

Scar Endometriosis After Cesarean Section; Our Clinical Experiences, 32 Cases of Cesarean Scar Endometriosis

Year 2024, , 96 - 101, 27.09.2024
https://doi.org/10.5505/achmedj.2024.87587

Abstract

Introductıon: Scar endometriosis is a type of rare endometriosis that develops following obstetric or gynecological surgeries. The aim of our study is to share our clinical experiences regarding scar endometriosis, which is becoming more common due to increasing cesarean operations, and to contribute to the literature on this subject.
Methods: A total of 32 patients who underwent surgery due to scar endometriosis participated in our study. The patients’ demographic and clinical characteristics, size and location of the lesion determined by imaging methods and histopathological results were recorded and analyzed.
Results: The mean age of the patients was 34.81±6.52 years, with 46.9% having undergone one cesarean section and 53.1% having undergone two or more cesarean sections. Scar endometriosis involving subcutaneous and fascial tissue was determined to be 43.7% in the right corner, 28.1% in the left corner, 9.4% in the midline, and 18.8% within the rectus muscle. The time elapsed between cesarean section and the onset of symptoms was found to be statistically significantly shorter in patients who had undergone two or more cesarean sections compared to those with only one previous cesarean section (p=0.015).
Conclusion: Scar endometriosis is a painful condition for which clear success in medical treatment has not yet been demonstrated, and surgical intervention is often required. Given the higher frequency of occurrence at the corners of cesarean section incisions, we recommend the careful washing of these corners. Further immunohistochemical studies are needed to achieve success in medical treatment, and histopathological analysis should be fully elucidated.

References

  • 1. Nisolle M, Alvarez ML, Colombo M, Foidart JM. [Pathogenesis of endometriosis]. Gynecol Obstet Fertil. 2007; 35: 898-903.
  • 2. Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ. Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol. 2004; 160: 784-796.
  • 3. Prescott J, Farland LV, Tobias DK et al. A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod. 2016; 31: 1475-1482.
  • 4. Nominato NS, Prates LF, Lauar I, Morais J, Maia L, Geber S. Caesarean section greatly increases risk of scar endometriosis. Eur J Obstet Gynecol Reprod Biol. 2010; 152: 83-85.
  • 5. Uzuncakmak C, Guldas A, Ozcam H, Dinç K. Scar endometriosis: a case report of this uncommon entity and review of the literature. Case Rep Obstet Gynecol. 2013; 2013: 386783.
  • 6. Buscemi S, Maiorana A, Fazzotta S et al. Scar endometriosis: not a rare cause for a painful scar. Clin Ter. 2021; 172: 129-133.
  • 7. Horton JD, Dezee KJ, Ahnfeldt EP, Wagner M. Abdominal wall endometriosis: a surgeon’s perspective and review of 445 cases. Am J Surg. 2008; 196: 207-212.
  • 8. Zhang P, Sun Y, Zhang C et al. Cesarean scar endometriosis: presentation of 198 cases and literature review. BMC Womens Health. 2019; 19: 14.
  • 9. Hirata T, Koga K, Osuga Y. Extra-pelvic endometriosis: A review.Reprod Med Biol. 2020; 19: 323-333.
  • 10. Youssef AT. The ultrasound of subcutaneous extrapelvic endometriosis. J Ultrason. 2020; 20: e176-e180.
  • 11. Pas K, Joanna SM, Renata R, Skręt A, Barnaś E. Prospective study concerning 71 cases of caesarean scar endometriosis (CSE). J Obstet Gynaecol. 2017; 37: 775-778.
  • 12. Benedetto C, Cacozza D, de Sousa Costa D et al. Abdominal wall endometriosis: Report of 83 cases. Int J Gynaecol Obstet. 2022; 159: 530-536.
  • 13. Durairaj A, Sivamani H, Panneerselvam M. Surgical Scar Endometriosis: An Emerging Enigma. Cureus. 2023; 15: e35089.
  • 14. Seckin KD, Kadirogullari P. Is dienogest a convenient treatment option for cesarean scar endometriosis or should it be treated surgically? Eur J Obstet Gynecol Reprod Biol. 2023; 282: 110-115.
  • 15. Dwivedi U, Shukla S, Anand N, Parashar C, Husain N. Scar Endometriosis: Cytological Diagnosis. JNMA J Nepal Med Assoc. 2018; 56: 550-552.
  • 16. Szubert M, Nowak-Gluck A, Domanska-Senderowska D et al. miR 31-3p Has the Highest Expression in Cesarean Scar Endometriosis. Int J Mol Sci. 2022; 23.
  • 17. Carsote M, Terzea DC, Valea A, Gheorghisan-Galateanu AA. Abdominal wall endometriosis (a narrative review). Int J Med Sci. 2020; 17: 536-542.
  • 18. Knorren ER, de Ridder LA, Nijholt IM et al. Effectiveness and complication rates of high intensity focused ultrasound treatment for abdominal wall endometriosis: A systematic review. Eur J Obstet Gynecol Reprod Biol. 2024 Mar 26;297:15-23.
  • 19. Marras S, Pluchino N, Petignat P et al. Abdominal wall endometriosis: An 11-year retrospective observational cohort study. Eur J Obstet Gynecol Reprod Biol X. 2019; 4: 100096.
  • 20. Mihailovici A, Rottenstreich M, Kovel S, Wassermann I, Smorgick N, Vaknin Z. Endometriosis-associated malignant transformation in abdominal surgical scar: A PRISMA-compliant systematic review. Medicine (Baltimore). 2017; 96: e9136.
There are 20 citations in total.

Details

Primary Language English
Subjects Traditional, Complementary and Integrative Medicine (Other)
Journal Section Research Articles
Authors

İnci Halilzade 0000-0002-3078-8420

Elcin İslek Secen 0000-0002-0892-8589

Gonca Türker Ergün 0000-0003-1064-8727

Filiz Avşar 0000-0003-3699-7757

Publication Date September 27, 2024
Submission Date July 22, 2024
Acceptance Date September 2, 2024
Published in Issue Year 2024

Cite

EndNote Halilzade İ, İslek Secen E, Türker Ergün G, Avşar F (September 1, 2024) Scar Endometriosis After Cesarean Section; Our Clinical Experiences, 32 Cases of Cesarean Scar Endometriosis. ACH Medical Journal 3 3 96–101.