Impact of long-term glycemic variability on interdialytic weight gain in diabetic hemodialysis patients

Year 2023, Volume: 5 Issue: 3, 192 - 195, 28.07.2023

Mustafa Topal , Muhammed Hasan Güler

https://doi.org/10.38053/acmj.1242127

Abstract

Aims: Interdialytic weight gain (IDWG) was shown to be associated with mortality and correlated with long-term glycemic indices in diabetic hemodialysis (DHD) patients. The aim of this study was to investigate the association between glycemic variability (GV) and IDWG in DHD patients.
Methods: 82 DHD patients were studied for 6 months. Six measurements of monthly predialysis glucose were used to calculate glycemic indices. The weight gain over the dry weight of the last 10 consequent hemodialysis sessions was measured for each patient to calculate IDWG.
Results: IDWG was positively correlated with GV, HbA1c (p=0.025, r=0.247 and p=0.006, r=0.304, respectively) and inversely correlated with age (p=0.01, r=-0.283). GV was positively correlated with HbA1c (p<0.001, r=0.638), mean predialysis glucose (p<0.001, r=0.737) and negatively correlated with serum sodium (p=0.014, r=-271). HbA1c and age were found to be independently related to IDWG after linear regression analysis.
Conclusion: GV should be taken into account to improve IDWG in DHD patients.

Keywords

Hemodialysis, interdialytic weight gain, diabetes mellitus, glycemic variability, HbA1c

Project Number

yok.

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