The relationship between nutritional parameters and pregnancy outcomes in abortus imminens

Year 2025, Volume: 7 Issue: 2, 184 - 189, 21.03.2025

Gülşan Karabay , Zeynep Şeyhanlı , Ahmet Arif Filiz , Betül Tokgöz Çakır , Gizem Aktemur , Nazan Vanlı Tonyalı , Umut Karabay , Salime Nur Afsar , Zehra Yılmaz

Abstract

Aims: Abortus imminens (AI) is defined as vaginal bleeding and/or pelvic pain before the 20th week of pregnancy. It affects approximately 20% of pregnancies. The HALP score, which integrates hemoglobin, albumin, lymphocyte, and platelet levels, is a marker of inflammation and nutritional status. This study investigates the association between the HALP score and AI and its potential role in predicting pregnancy outcomes.
Methods: This retrospective study was conducted at Ankara Etlik City Hospital between September 2022 and March 2024. A total of 254 patients with AI and 260 controls were included. Data on maternal demographics and laboratory parameters, including hemoglobin, albumin, lymphocyte, and platelet levels, were collected. Statistical analyses were performed using SPSS 22.0, with significance set at p<0.05.
Results: The HALP score was significantly higher in the AI group than in controls (p=0.002). However, no significant difference in HALP scores was observed between patients who experienced pregnancy loss and those who continued their pregnancies (p=0.350). Preterm birth, newborn intensive care unit admission, and respiratory distress were more frequent in AI cases.
Conclusion: The HALP score is a practical and cost-effective tool for diagnosing AI. Further studies are needed to explore its clinical utility.

Keywords

Abortus imminens, HALP score, nutrition, pregnancy outcomes

Ethical Statement

The Ankara Etlik City Hospital Ethics Committee gave its permission to the study protocol (approval number: AESH-BADEK-2024-1142). The Declaration of Helsinki's guidelines were followed in the conduct of this study.

Abortus İmminens'te Beslenme Parametreleri ve Gebelik Sonuçları Arasındaki İlişki

Abstract

Amaç: Abortus imminens (AI), gebeliğin 20. haftasından önce vajinal kanama ve/veya pelvik ağrı olarak tanımlanır. Gebeliklerin yaklaşık %20'sini etkiler. Hemoglobin, albümin, lenfosit ve trombosit seviyelerini birleştiren HALP skoru, inflamasyon ve beslenme durumunu gösteren bir belirteçtir. Bu çalışmada, HALP skoru ile AI arasındaki ilişki ve gebelik sonuçlarını tahmin etmedeki potansiyel rolü araştırılmaktadır.
Yöntemler: Bu retrospektif çalışma Eylül 2022 ile Mart 2024 tarihleri arasında Ankara Etlik Şehir Hastanesi'nde gerçekleştirildi. Toplam 254 AI hastası ve 260 kontrol dahil edildi. Maternal demografik verileri ve hemoglobin, albümin, lenfosit ve trombosit seviyeleri gibi laboratuvar parametrelerine ilişkin veriler toplandı. İstatistiksel analizler SPSS 22.0 kullanılarak yapıldı ve anlamlılık p<0,05 olarak belirlendi.
Bulgular: HALP skoru AI grubunda kontrollerden anlamlı olarak daha yüksekti (p=0,002). Ancak AI tanısı alıp abort eden hastalar ile gebeliklerine devam eden hastalar arasında HALP skorlarında anlamlı bir fark gözlenmedi (p=0,350). AI vakalarında erken doğum, yenidoğan yoğun bakıma yatış ve solunum sıkıntısı daha sıktı.
Sonuç: HALP skoru AI tanısı için pratik ve maliyet etkin bir araçtır. Klinik faydasını araştırmak için daha fazla çalışmaya ihtiyaç vardır.

Keywords

Abortus imminens, HALP skoru, beslenme, gebelik sonuçları

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