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Year 2017, Volume: 1 Issue: 1, 11 - 19, 28.12.2017

Alper Çolak , Murat Taş , Gazi İrez Orhan Büyükgüngör , Ferdağ Çolak Handan Günay

Abstract

References

  • Reference 1 W. H.Correa, S. Papadopoulos, P. Radnidge, B. A. Roberts, J. L. Scott, Green Chem. 2002, 4, 245-251. Reference 2 A. Göblöys, L. Lázár, F. Fülöp, Tetrahedron 2002, 58, 1011-1016. Reference 3 J. Sinkkonen, K. N. Zelenin, A. K. A. Potapov, I. V. Lagoda, V. V. Alekseyev, K. Pihlaja, Tetrahedron 2003, 59, 1939-1950. Reference 4 K. Tanaka, R. Shiraishi, Green Chem. 2000, 2, 272-273. Reference 5 A. T. Çolak, M. Taş, G. İrez, O. Z. Yeşilel, O. Büyükgüngör, Z. Anorg. Allg. Chem. 2007, 633, 504-508. Reference 6 National committee for clinical laboratory standards (NCCLS) Performance standards for antimicrobial disk susceptibility tests. Approved standard (M2-A4). National committee for clinical laboratory standards Villanova, PA. 1990a. Reference 7 National committee for clinical laboratory standards. Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobically. Approved standard (M7-A2). National committee for clinical laboratory standards, Villanova, PA. 1990b. Reference 8 Stoe&Cie, X-Area (Version 1.18) and X-Red32 (Version 1.04), Stoe&Cie. Darmstadt, Germany, 2002. Reference 9 M.C. Burla, R. Caliandro, M. Camalli, B. Carrozzini, G. L. Cascarano, L. D. Caro, C. Giacovazzo, G. Polidori, R. Spagna, J. Appl. Crystallogr. 2005, 38, 381-388. Reference 10 Sheldrick G.M. SHELXL-97: Program for the Refinement of Crystal Structures. (Germany University of Göttingen), 1997. Reference 11 C.K. Johnson, M.N. Burnett, ORTEP-III (version 1.0.2), Rep. ORNL-6895, Oak Ridge National Laboratory, Oak Ridge, TN (USA) (1996). Windows version: Farrugia L.J., University of Glasgow, Glasgow, Scotland (U.K.), 1997. Reference 12 L. J. Farrugia, J. Appl. Crystallogr. 1999, 32, 837-838. Reference 13 Á. Somogyi, Medical applications of Mass Spectrometry, K. Vékey, A. Telekes and A. Vertes (editors) Elsevier B.V. 2008. Reference 14 L. Bajpai, M. Varshney, C. N. Seubert, S. M. J. Stevens, J. V. Johnson, R. A. Yost, D. M. Dennis, J. Am. Soc. Mass Spectrom. 2005, 16, 814-824. Reference 15 M. Taş, H. Batı, J. Chem. Res. 2006, 87-92. Reference 16 A. Zülfikaroğlu, M. Taş, H. Batı, B. Batı, Synth. React. Inorg.Met. Org. Chem. 2003, 33, 625-638. Reference 17 H. Batı, M. Taş, B. Batı, Synth. React. Inorg. Met. Org. Chem. 2001, 31, 541-548. Reference 18 H. Batı, M. Taş, M. Macit, Synth. React. Inorg. Met. Org.Chem. 1998, 28, 1371-1380. Reference 19 M. V. Barybin, P. L. Diaconescu, C. C. Cummins, Inorg. Chem. 2001, 40, 2892-2897. Reference 20 S. Sevagapandian, G. Rajagopal, K. Nehru, P. Athappan, Trans. Metal Chem. 2000, 25, 388-393. Reference 21 R. M. Srivastava, I. M. Brinn, J. O. Machura-Herrera, H. B. Faria, G. B. Carpenter, D. Andrade, C.G. Venkatesh, L. P. F. Morais, J. Mol. Struct. 1997, 406, 159-167. Reference 22 F. Karipçin, H. I. Uçan, I. Karataş, Trans. Metal Chem. 2002, 27, 813-817. Reference 23 M. Taş, H. Batı, J. Therm. Anal. Cal. 2006, 85, 295-299. Reference 24 B. K. Singh, U. K., Jetley, R. K., Sharma, B. S. Garg, Spectrochimica Acta Part A 2007, 68, 63-73. Reference 25 N. Tounsi, L. Dupont, A. Mohamadou, E. Guillon, M. Aplincourt, G. Rogez, Polyhedron 2008, 27, 674-3682. Reference 26 M. C. Fernández-Fernández, R. B. Calle, A. Macías, L. V. Matarranz, P. P. Lourido, Polyhedron 2008, 27, 2301-2308. Reference 27 F. Hamurcu, A. B. Gündüzalp, S. Çete S., B. Erk, Tran. Met. Chem. 2008, 33, 137-141.

Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes

Year 2017, Volume: 1 Issue: 1, 11 - 19, 28.12.2017

Alper Çolak , Murat Taş , Gazi İrez Orhan Büyükgüngör , Ferdağ Çolak Handan Günay

Abstract

The
2-methyl-2-(1-hydroxyiminoethyl)-1,2,3,4-tetrahydroquinazoline (HL or 1) and its novel Ni(II) complexes, square-planar
[Ni(L)(LH)]·(NO3) (2) and
octahedral [NiCl2(LH)(H2O)2]·(H2O) (3), have been synthesized. The ligand and complexes
have been characterized by means of elemental, IR, UV-Vis. spectroscopic
studies, 1H-NMR, 13C-NMR, magnetic susceptibility,
thermal analysis, mass spectroscopy and X-ray diffraction technique. The HL
ligand crystallizes in the P21/c. Antimicrobial activity of ligand (1) and complexes (2 and 3) was evaluated by
the agar diffusion method. Complex 2 showed weak antimicrobial activity against
tested microorganism strains. Complex 3 exhibited moderate antimicrobial activity
against Staphylococcus epidermidis
and Candida albicans.

Keywords

antimicrobial activity nickel complex oxime 1 2 3

References

  • Reference 1 W. H.Correa, S. Papadopoulos, P. Radnidge, B. A. Roberts, J. L. Scott, Green Chem. 2002, 4, 245-251. Reference 2 A. Göblöys, L. Lázár, F. Fülöp, Tetrahedron 2002, 58, 1011-1016. Reference 3 J. Sinkkonen, K. N. Zelenin, A. K. A. Potapov, I. V. Lagoda, V. V. Alekseyev, K. Pihlaja, Tetrahedron 2003, 59, 1939-1950. Reference 4 K. Tanaka, R. Shiraishi, Green Chem. 2000, 2, 272-273. Reference 5 A. T. Çolak, M. Taş, G. İrez, O. Z. Yeşilel, O. Büyükgüngör, Z. Anorg. Allg. Chem. 2007, 633, 504-508. Reference 6 National committee for clinical laboratory standards (NCCLS) Performance standards for antimicrobial disk susceptibility tests. Approved standard (M2-A4). National committee for clinical laboratory standards Villanova, PA. 1990a. Reference 7 National committee for clinical laboratory standards. Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobically. Approved standard (M7-A2). National committee for clinical laboratory standards, Villanova, PA. 1990b. Reference 8 Stoe&Cie, X-Area (Version 1.18) and X-Red32 (Version 1.04), Stoe&Cie. Darmstadt, Germany, 2002. Reference 9 M.C. Burla, R. Caliandro, M. Camalli, B. Carrozzini, G. L. Cascarano, L. D. Caro, C. Giacovazzo, G. Polidori, R. Spagna, J. Appl. Crystallogr. 2005, 38, 381-388. Reference 10 Sheldrick G.M. SHELXL-97: Program for the Refinement of Crystal Structures. (Germany University of Göttingen), 1997. Reference 11 C.K. Johnson, M.N. Burnett, ORTEP-III (version 1.0.2), Rep. ORNL-6895, Oak Ridge National Laboratory, Oak Ridge, TN (USA) (1996). Windows version: Farrugia L.J., University of Glasgow, Glasgow, Scotland (U.K.), 1997. Reference 12 L. J. Farrugia, J. Appl. Crystallogr. 1999, 32, 837-838. Reference 13 Á. Somogyi, Medical applications of Mass Spectrometry, K. Vékey, A. Telekes and A. Vertes (editors) Elsevier B.V. 2008. Reference 14 L. Bajpai, M. Varshney, C. N. Seubert, S. M. J. Stevens, J. V. Johnson, R. A. Yost, D. M. Dennis, J. Am. Soc. Mass Spectrom. 2005, 16, 814-824. Reference 15 M. Taş, H. Batı, J. Chem. Res. 2006, 87-92. Reference 16 A. Zülfikaroğlu, M. Taş, H. Batı, B. Batı, Synth. React. Inorg.Met. Org. Chem. 2003, 33, 625-638. Reference 17 H. Batı, M. Taş, B. Batı, Synth. React. Inorg. Met. Org. Chem. 2001, 31, 541-548. Reference 18 H. Batı, M. Taş, M. Macit, Synth. React. Inorg. Met. Org.Chem. 1998, 28, 1371-1380. Reference 19 M. V. Barybin, P. L. Diaconescu, C. C. Cummins, Inorg. Chem. 2001, 40, 2892-2897. Reference 20 S. Sevagapandian, G. Rajagopal, K. Nehru, P. Athappan, Trans. Metal Chem. 2000, 25, 388-393. Reference 21 R. M. Srivastava, I. M. Brinn, J. O. Machura-Herrera, H. B. Faria, G. B. Carpenter, D. Andrade, C.G. Venkatesh, L. P. F. Morais, J. Mol. Struct. 1997, 406, 159-167. Reference 22 F. Karipçin, H. I. Uçan, I. Karataş, Trans. Metal Chem. 2002, 27, 813-817. Reference 23 M. Taş, H. Batı, J. Therm. Anal. Cal. 2006, 85, 295-299. Reference 24 B. K. Singh, U. K., Jetley, R. K., Sharma, B. S. Garg, Spectrochimica Acta Part A 2007, 68, 63-73. Reference 25 N. Tounsi, L. Dupont, A. Mohamadou, E. Guillon, M. Aplincourt, G. Rogez, Polyhedron 2008, 27, 674-3682. Reference 26 M. C. Fernández-Fernández, R. B. Calle, A. Macías, L. V. Matarranz, P. P. Lourido, Polyhedron 2008, 27, 2301-2308. Reference 27 F. Hamurcu, A. B. Gündüzalp, S. Çete S., B. Erk, Tran. Met. Chem. 2008, 33, 137-141.
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Details

Primary Language English
Subjects Chemical Engineering
Journal Section Research Articles
Authors

Alper Çolak

Murat Taş

Gazi İrez This is me

Orhan Büyükgüngör

Ferdağ Çolak This is me

Handan Günay

Publication Date December 28, 2017
Published in Issue Year 2017 Volume: 1 Issue: 1

Cite

APA Çolak, A., Taş, M., İrez, G., Büyükgüngör, O., et al. (2017). Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes. Acta Materialia Turcica, 1(1), 11-19.
AMA Çolak A, Taş M, İrez G, Büyükgüngör O, Çolak F, Günay H. Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes. ACTAMAT. December 2017;1(1):11-19.
Chicago Çolak, Alper, Murat Taş, Gazi İrez, Orhan Büyükgüngör, Ferdağ Çolak, and Handan Günay. “Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-Tetrahydroquinazoline and Its Nickel(II) Complexes”. Acta Materialia Turcica 1, no. 1 (December 2017): 11-19.
EndNote Çolak A, Taş M, İrez G, Büyükgüngör O, Çolak F, Günay H (December 1, 2017) Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes. Acta Materialia Turcica 1 1 11–19.
IEEE A. Çolak, M. Taş, G. İrez, O. Büyükgüngör, F. Çolak, and H. Günay, “Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes”, ACTAMAT, vol. 1, no. 1, pp. 11–19, 2017.
ISNAD Çolak, Alper et al. “Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-Tetrahydroquinazoline and Its Nickel(II) Complexes”. Acta Materialia Turcica 1/1 (December 2017), 11-19.
JAMA Çolak A, Taş M, İrez G, Büyükgüngör O, Çolak F, Günay H. Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes. ACTAMAT. 2017;1:11–19.
MLA Çolak, Alper et al. “Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-Tetrahydroquinazoline and Its Nickel(II) Complexes”. Acta Materialia Turcica, vol. 1, no. 1, 2017, pp. 11-19.
Vancouver Çolak A, Taş M, İrez G, Büyükgüngör O, Çolak F, Günay H. Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes. ACTAMAT. 2017;1(1):11-9.
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