Case Report
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COVID-19 HASTASINDA AKALKÜLÖZ AKUT PANKREATİT ; NADİR BİR OLGU SUNUMU

Year 2022, , 32 - 35, 27.02.2022
https://doi.org/10.53446/actamednicomedia.946961

Abstract

Dünya Sağlık Örgütü tarafindan pandemi olarak ilan edilen COVID-19 enfeksiyonu birincil olarak solunum sistemini etkiliyor gibi görünse de gastrointestinal system semptomlarının önemi ve tanınmasi giderek artmaktadir. Olgumuzda COVID-19 pnömonisi ile birlikte akut pankreatit bulgulari ile başvuran bir hastayı sunmayı amaçladik. Hipertansiyon ve koroner arter hastalığı olduğu bilinen 75 yaşinda kadın hasta, kuşak tipi epigastrik ağri, bulanti ve nefes darliği şikayeti ile acil servise başvurmuştur. Laboratuvar değerleri ve görüntüleme yöntemleri ile akut pankreatit tanısı konulan hasta, COVID-19 testinin pozitif çikmasi ve oksijen ihtiyaci nedeniyle yoğun bakima yatırılmıştır. Pankreatit için herhangi risk faktörü olmayan hastada COVID-19 enfeksiyonu ile korele pankreatit görülmüştür. Bu olgu, COVID-19'un yeni bir viral pankreatit etkeni olabileceği veya var olan bir pankreatitin şiddetini artirabileceği veya bunlardan bağimsiz olarak otoimmüniteyi tetikleyebileceği hipotezlerini düşündürmektedir. Bu görüşü desteklemek için COVID-19 hastalari üzerinde çok sayida çalişmaya ihtiyaç vardir.

References

  • 1. Chiarello M.M, Cariati M, Brisinda G. Assessment of severity of acute pancreatitis in a Sars‐CoV‐2 pandemia Br J Surg. 2020;10.1002/bjs.11818.
  • 2. Meireles, P. A., Bessa, F., Gaspar, P., Parreira, I., Silva, V. D., Mota, C., & Alvoeiro, L. (2020). Acalculous acute pancreatitis in a COVID-19 patient. European journal of case reports in inter-nal medicine, 7(6).
  • 3. Aloysius, M. M., Thatti, A., Gupta, A., Sharma, N., Bansal, P., & Goyal, H. (2020). COVID-19 presenting as acute pancreatitis. Pancreatology, 20(5), 1026-1027.
  • 4. Hadi A, Werge M, Kristiansen K.T, Pedersen U.G, John Gásdal Karstensen, Novovic, Gluud L.L. Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members Pancreatology. 2020 Jun;20(4):665-667. doi: 10.1016/j.pan.2020.04.021.
  • 5. Wang F, Wang H,Fan J, Zhang Y, Wang H,Zhao Q. Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia. Gastroenterology. 2020 Jul; 159(1): 367–370. doi: 10.1053/j.gastro.2020.03.055
  • 6. Miró, Ò., Llorens, P., Jiménez, S., Piñera, P., Burillo-Putze, G., Martín, A., ... & Del Castillo, J. G. (2020). Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S1. Epidemiology & Infection, 148.
  • 7. Inamdar S, Benias PC, Liu Y, et al. Prevalence, Risk Factors, and Outcomes of Hospitalized Patients With Coronavirus Disease 2019 Presenting as Acute Pancreatitis. Gastroenterology. 2020;159(6):2226-8.e2.
  • 8. Yang, J. K., Feng, Y., Yuan, M. Y., Yuan, S. Y., Fu, H. J., Wu, B. Y., ... & Chan, J. C. N. (2006). Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabetic medicine, 23(6), 623-628
  • 9. Liu, F., Long, X., Zhang, B., Zhang, W., Chen, X., & Zhang, Z. (2020). ACE2 expression in pancreas may cause pancreatic damage after SARS-CoV-2 infection. Clinical Gastroenterology and Hepatology, 18(9), 2128-2130.
  • 10. Mazrouei S.S.A ,Saeed G.A, Helali A.A.A. COVID-19-associated acute pancreatitis: a rare cause of acute abdomen Radiol Case Rep. 2020 Jun 11;15(9):1601-1603. doi: 10.1016/j.radcr.2020.06.019.
  • 11. Dirweesh A, Li Y, Trikudanathan G, Mallery J. S, Freeman M.L, Amateau S.K. Clinical Out-comes of Acute Pancreatitis in Patients With Coronavirus Disease 2019 Gastroenterology. 2020; doi: 10.1053/j.gastro.2020.07.038
  • 12. Kumaran N.K, Karmakar B.K, Taylor O.M Coronavirus disease-19 (COVID-19) associated with acute necrotising pancreatitis (ANP) BMJ Case Rep. 2020 Sep 7;13(9):e237903. doi: 10.1136/bcr-2020-237903
  • 13. Jin, D. X., Yang, A. L., Suleiman, S. L., McNabb-Baltar, J., & Banks, P. A. (2019). Tu1424–Marked Se-rum Lipase Elevations are Associated with Longer Hospitalizations in Patients with Non-Pancreatic Hy-perlipasemia. Gastroenterology, 156(6), S-1033.
  • 14. Banks PA, Bollen TL, Dervenis C et al. Classification of acute pancreatitis — 2012: revision of the Atlanta classification and definitions by international consensus. Gout. 2013; 62: 102-111

ACALCULOUS ACUTE PANCREATITIS IN A COVID-19 PATIENT: A RARE CASE REPORT

Year 2022, , 32 - 35, 27.02.2022
https://doi.org/10.53446/actamednicomedia.946961

Abstract

Although COVID-19 infection, declared as a pandemic by the World Health Organization, seems to affect the primary respiratory system, the importance and recognition of gastrointestinal symptoms are gradually increasing. In our case, we aimed to present a patient who presented with signs of acute pancreatitis concurrent with COVID-19 infection. A 75-year-old female patient, known to have hypertension and coronary artery disease, was admitted to the emergency department with the complaint of generation-style epigastric pain , nausea and dyspnoea. The patient, who was diagnosed with acute pancreatitis by laboratory values and imaging methods, was taken to intensive care due to positive COVID-19 test and oxygen demand. Pancreatitis was seen with COVID-19 infection in the patient without risk factors for pancreatitis.This case suggests hypotheses that COVID-19 could be a new viral pancreatitis agent or increase the severity of an existing pancreatitis or trigger autoimmunity independent of them. numerous studies on covid-19 patients are needed to support this view.

References

  • 1. Chiarello M.M, Cariati M, Brisinda G. Assessment of severity of acute pancreatitis in a Sars‐CoV‐2 pandemia Br J Surg. 2020;10.1002/bjs.11818.
  • 2. Meireles, P. A., Bessa, F., Gaspar, P., Parreira, I., Silva, V. D., Mota, C., & Alvoeiro, L. (2020). Acalculous acute pancreatitis in a COVID-19 patient. European journal of case reports in inter-nal medicine, 7(6).
  • 3. Aloysius, M. M., Thatti, A., Gupta, A., Sharma, N., Bansal, P., & Goyal, H. (2020). COVID-19 presenting as acute pancreatitis. Pancreatology, 20(5), 1026-1027.
  • 4. Hadi A, Werge M, Kristiansen K.T, Pedersen U.G, John Gásdal Karstensen, Novovic, Gluud L.L. Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members Pancreatology. 2020 Jun;20(4):665-667. doi: 10.1016/j.pan.2020.04.021.
  • 5. Wang F, Wang H,Fan J, Zhang Y, Wang H,Zhao Q. Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia. Gastroenterology. 2020 Jul; 159(1): 367–370. doi: 10.1053/j.gastro.2020.03.055
  • 6. Miró, Ò., Llorens, P., Jiménez, S., Piñera, P., Burillo-Putze, G., Martín, A., ... & Del Castillo, J. G. (2020). Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S1. Epidemiology & Infection, 148.
  • 7. Inamdar S, Benias PC, Liu Y, et al. Prevalence, Risk Factors, and Outcomes of Hospitalized Patients With Coronavirus Disease 2019 Presenting as Acute Pancreatitis. Gastroenterology. 2020;159(6):2226-8.e2.
  • 8. Yang, J. K., Feng, Y., Yuan, M. Y., Yuan, S. Y., Fu, H. J., Wu, B. Y., ... & Chan, J. C. N. (2006). Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabetic medicine, 23(6), 623-628
  • 9. Liu, F., Long, X., Zhang, B., Zhang, W., Chen, X., & Zhang, Z. (2020). ACE2 expression in pancreas may cause pancreatic damage after SARS-CoV-2 infection. Clinical Gastroenterology and Hepatology, 18(9), 2128-2130.
  • 10. Mazrouei S.S.A ,Saeed G.A, Helali A.A.A. COVID-19-associated acute pancreatitis: a rare cause of acute abdomen Radiol Case Rep. 2020 Jun 11;15(9):1601-1603. doi: 10.1016/j.radcr.2020.06.019.
  • 11. Dirweesh A, Li Y, Trikudanathan G, Mallery J. S, Freeman M.L, Amateau S.K. Clinical Out-comes of Acute Pancreatitis in Patients With Coronavirus Disease 2019 Gastroenterology. 2020; doi: 10.1053/j.gastro.2020.07.038
  • 12. Kumaran N.K, Karmakar B.K, Taylor O.M Coronavirus disease-19 (COVID-19) associated with acute necrotising pancreatitis (ANP) BMJ Case Rep. 2020 Sep 7;13(9):e237903. doi: 10.1136/bcr-2020-237903
  • 13. Jin, D. X., Yang, A. L., Suleiman, S. L., McNabb-Baltar, J., & Banks, P. A. (2019). Tu1424–Marked Se-rum Lipase Elevations are Associated with Longer Hospitalizations in Patients with Non-Pancreatic Hy-perlipasemia. Gastroenterology, 156(6), S-1033.
  • 14. Banks PA, Bollen TL, Dervenis C et al. Classification of acute pancreatitis — 2012: revision of the Atlanta classification and definitions by international consensus. Gout. 2013; 62: 102-111
There are 14 citations in total.

Details

Primary Language English
Subjects Intensive Care
Journal Section Olgu Sunumu
Authors

Ayşe Ayyıldız 0000-0002-8206-6921

Ayşegül Çınaroğlu This is me 0000-0002-3557-5539

Birgül Yelken 0000-0001-9677-9028

Publication Date February 27, 2022
Submission Date June 3, 2021
Acceptance Date December 5, 2021
Published in Issue Year 2022

Cite

AMA Ayyıldız A, Çınaroğlu A, Yelken B. ACALCULOUS ACUTE PANCREATITIS IN A COVID-19 PATIENT: A RARE CASE REPORT. Acta Med Nicomedia. February 2022;5(1):32-35. doi:10.53446/actamednicomedia.946961

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