Empagliflozine Bağlı Gelişen Öglisemik Diyabetik Ketoasidoz; Olgu Sunumu

Year 2021, Volume: 4 Issue: 3, 87 - 89, 30.10.2021

Pınar Karabacak , Süleyman Çelik Ayşe Kösem Mustafa Soner Özcan , Eyyüp Sabri Özden

https://doi.org/10.53446/actamednicomedia.925223

Abstract

Hiperglisemi (Kan şekeri> 250 mg/dL), metabolik asidoz (pH < 7,3), ketozis diyabetik ketoasidozun tanı kriterleri olarak belirtilmektedir. Nadiren kan şekeri 250 mg/dL altında diyabetik ketoasidoz görülebilmektedir. Bu durum öglisemik diyabetik ketoasidoz olarak adlandırılmaktadır. Nadir bir durum olmasına rağmen normal bir glukoz düzeyi tanıdan uzaklaştırabileceği için tedavinin gecikmesine ve bunun sonucunda artmış morbidite ve mortaliteye sebep olabilir. Sodyum-glukoz ko-transporter 2 (SGLT-2) inhibitörleri, diyabetes mellitus tedavisinde kullanılan yeni kuşak oral antidiyabetik ilaçlardır. Öglisemik diyabetik ketoasidoz gibi, nadir fakat ciddi advers etkileri vardır.
Bu olgu sunumunda, nadir görülen bir durum olan empagliflozin kullanımına bağlı gelişen öglisemik diyabetik ketoasidoz olgusunun sunulması amaçlanmıştır.

Keywords

Empagliflozin, Öglisemik Diyabeti Ketoasidoz, Sodyum-glukoz ko-transporter 2 (SGLT-2) inhibitörleri

Euglycemic diabetic ketoacidosis due to empagliflozin; A Case Report

Abstract

Hyperglycemia (Blood glucose> 250 mg / dL), metabolic acidosis (pH <7.3), ketosis are specified as diagnostic criteria for diabetic ketoacidosis. Rarely, diabetic ketoacidosis can be seen with blood glucose below 250 mg / dL. This condition is called euglycemic diabetic ketoacidosis. Although it is a rare condition, a normal glucose level may lead to delay in treatment and consequently increased morbidity and mortality, as it may distract from the diagnosis. Sodium-glucose co-transporter 2 (SGLT-2) inhibitors are new generation oral antidiabetic drugs used in the treatment of diabetes mellitus. There are rare but serious adverse drug effects, including euglycemic diabetic ketoacidosis
In this case report, we aimed to present a case of euglycemic diabetic ketoacidosis due to empagliflozin use, which is a rare condition.

Keywords

Empagliflozin, Euglycemıc Dıabetıc Ketoacıdosıs, Sodium-glucose co-transporter 2 (SGLT-2) inhibitors

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