Fragmente QRS Paterni Sepsis ve Septik Şokta Kötü Prognozu Öngörür

Year 2024, Volume: 7 Issue: 3, 257 - 262, 27.10.2024

Pınar Karabacak , Mustafa Karabacak , Özlem Polat , Yağmur Kara

Abstract

Amaç: Sepsise bağlı miyokardiyal disfonksiyon, yüksek mortalite oranı ile ilişkili klinik bir durumdur. Parçalanmış QRS (fQRS) miyokardın fonksiyonu ile ilişkili bir belirteçtir. Bu çalışmanın amacı fQRS paternlerinin kısa dönem genel sağkalım (OS) ile ilişkili olup olmadığını belirlemektir.
Yöntem: Çalışmaya 76 sepsis ve 68 septik şok hastası dahil edildi. SOFA skoru ve APACHE II skoru hesaplandı ve fQRS paterni değerlendirildi.
Bulgular: Septik şok grubunda APACHE II skoru, SOFA skoru ve mortalite anlamlı olarak daha yüksekti [sırasıyla 38 (%50) vs 45 (%65); p<0.01]. Mekanik ventilasyon süresi, fQRS paterni ve hastanede yatış süresi mortaliteyi öngörmüştür. FQRS paterninin varlığı her iki grupta da kısa dönem sağkalımda azalma ile ilişkilendirilmiştir
Sonuç: fQRS paterni ve mortalite özellikle septik şoklarda anlamlı olarak daha yüksekti. Bununla birlikte, her iki grupta da fQRS varlığının mortalite ile korelasyon gösterdiği ve bağımsız olarak daha kötü OS'yi öngördüğü bulunmuştur. Bu nedenle, fQRS paterninin septik hastalar için yeni bir prognostik gösterge olabileceğini düşünüyoruz.

Keywords

Sepsis, Septik Şok, Elektrokardiyografi, Fragmente QRS

Ethical Statement

Etik Kurul Belgesi sisteme yüklenmiştir.

Fragmented QRS Pattern Predicts Poor Prognosis in Sepsis and Septic Shock

Abstract

Objective: Myocardial dysfunction due to sepsis is a clinical condition associated with a high rate of mortality. Fragmented QRS (fQRS) is a marker that is associated with the function of the myocardium. This study aimed to determine whether fQRS patterns were associated with short-term overall survival(OS).
Methods: 76 patients with sepsis and 68 patients with septic shock were included in the study. SOFA score and APACHE II score were calculated, and the fQRS pattern has been assessed..
Results: In the septic shock group, APACHE II score, SOFA score and mortality were significantly higher [38 (%50) vs 45 (%65), respectively; p<0.01]. Duration of mechanical ventilation, the fQRS pattern, and hospitalization time predicted the mortality. The fQRS pattern's presence was linked to a decreased short-term survival in both groups
Conclusion: fQRS pattern and mortality were significantly higher especially septic shocks. However, in both groups, the presence of the fQRS has been found to have a correlation with mortality and independently predicted worse OS. Thus, we propose that the fQRS pattern could serve as a novel prognostic indicator for septic patients.

Keywords

Sepsis, Septic Shock, Electrocardiography, Fragmented QRS

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