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Evaluation of Dentists' Awareness, Knowledge, and Attitude towards Dental Stem Cells

Year 2024, Volume: 13 Issue: 3, 426 - 434, 24.09.2024
https://doi.org/10.54617/adoklinikbilimler.1464338

Abstract

Objective: Various adult stem cell populations exist in dental tissues. These are known as dental stem cells. Dentists play an active role in the collection, preservation, and inclusion of dental stem cells into treatment processes. This study aimed to evaluate dentists' awareness regarding dental stem cells as well as their knowledge and attitudes towards dental stem cells. The study included dentists with different professional experience.
Materials and Methods: In this study, a total sample size consisting of 112 dentists working in different sectors in Ankara province in May-June 2023 and having different professional experience periods was selected. A self-administered and hand-delivered questionnaire consisting of 22 items was used to evaluate dentists' awareness, knowledge, and attitude toward dental stem cells. The results were statistically analyzed by using the chi-squared test.
Results: 96.4% of the participants had knowledge about stem cells, while 82.1% had knowledge about dental stem cells. 11.6% of those who had knowledge about dental stem cells found their knowledge sufficient. 58% of the participants had knowledge that there were stem cell banks in Turkey. 83.7% of those with <5 years of professional experience, 85.4% of those with 5-15 years of professional experience and 72.7% of those with >15 years of professional experience had awareness regarding dental stem cells (p=0.428). The rate of awareness towards stem cell banks was significantly lower in those with <5 years of professional experience (p=0.016).
Conclusion: This study reveals that dentists have a high awareness of dental stem cells but do not have sufficient knowledge about their basic features. Dentists need knowledge content that starts with undergraduate education about dental stem cell sources and stem cell banks and continues with postgraduate education programs.

References

  • Chitroda P, Katti G, Attar N, Shahbaz S, Sreenivasarao G, Patil A. Stem cells in dentistry: A study regarding awareness of stem cells among dental professionals. Indian Journal of Dental Research. 2017;28(6):711-716.
  • Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences. 2000;97(25),13625-13630.
  • Huang YH, Yang JC, Wang CW, Lee SY. Dental Stem Cells and Tooth Banking for Regenerative Medicine. J Exp Clin Med. 2010;2(3):111-117.
  • Goswami M, Kumar G, Sharma S. “Dental Stem Cells”: Awareness, knowledge, and attitude of dental professionals—A cross-sectional study. Special Care in Dentistry. 2020;40(1):90-96.
  • Huang GTJ, Gronthos S, Shi S. Critical reviews in oral biology & medicine: Mesenchymal stem cells derived from dental tissues vs. those from other sources: Their biology and role in Regenerative Medicine. J Dent Res. 2009;88(9):792-806.
  • Derubeis AR, Cancedda R. Bone marrow stromal cells (BMSCs) in bone engineering: limitations and recent advances. Annals of biomedical engineering, 2004;32,160-165
  • Kwak KA, Lee SP, Yang JY, Park YS. Current perspectives regarding stem cell-based therapy for Alzheimer’s disease. Stem Cells Int. 2018;2018.
  • Lye JL, Soon LK, Ahmad WANW, Tan SC. Knowledge and attitude about stem cells and their application in medicine among nursing students in Universiti Sains Malaysia, Malaysia. The Malaysian journal of Medical Sciences: MJMS, 2015;22(4), 23
  • Deepika N, Devadiga S, Koshal N, Mittal S, Moidin T. Stem cells: A boon in dentistry. Journal of Dental Research and Review. 2015;2(1):47.
  • Vyas S, Vyas K, Satish M, Shende V, Srivastav R. Stem cells-The future of dentistry: A review. Journal of Indian Academy of Oral Medicine and Radiology. 2011;23(Suppl 1),S370-S372.
  • Mathur S, Chopra R, Pandit I, Srivastava N, Neeraj G. Stem cell research: applicability in dentistry. Int J Oral Maxillofac Implants. 2014;29(2):210-219.
  • Katge F, Shetty AJ, Rusawat B, Vamsi KC. Knowledge and attitude of Indian dentists regarding dental stem cells: A cross-sectional descriptive survey. Indian Journal of Dental Research. 2017;28(4):367-374.
  • Sede MA, Audu O, Azodo CC. Stem cells in Dentistry: Knowledge and attitude of Nigerian Dentists. BMC Oral Health. 2013;13(1).
  • Cord Blood Banking Regulation. Accessed March 29, 2024. https://www.mevzuat.gov.tr/mevzuat?MevzuatNo=8843&MevzuatTur=7&MevzuatTertip=5
  • Goomer P, Sidhu AK, Tuli P, Kansal S, Bansal K, Thakre GR. Awareness of stem cells & health implications of SHED found in pediatric dentition among Indian Population. Journal of International Oral Health. 2014;6(1),44.
  • Goyal A. Knowledge, awareness and attitude regarding stem cells among dental practitioners in Udaipur city, Rajasthan. International Journal of Advanced Research. 2015;677-684.
  • Abdulrazeq F, Kheirallah KA, Al-Mistarehi AH, Al Bashir S, ALQudah MA, Alzoubi A, et al. Effectiveness of interactive teaching intervention on medical students’ knowledge and attitudes toward stem cells, their therapeutic uses, and potential research applications. PeerJ, 2022;10,e12824.
  • Lipee D, Bhatt R, Bhatt A, Gurjar D, Dave L. Evaluating Awareness on Dental Pulp Stem Cells and its Applications amongst Graduating Dental Students of Ahmedabad and Gandhinagar District: A Cross-Sectional Survey. Human Biology Research Article Adv Hum Biol. 2014;4(3):54-59.

Diş Hekimlerinin Dental Kök Hücrelere Dair Bilgi, Farkındalık ve Tutumlarının Değerlendirilmesi

Year 2024, Volume: 13 Issue: 3, 426 - 434, 24.09.2024
https://doi.org/10.54617/adoklinikbilimler.1464338

Abstract

Amaç: Diş dokularında çeşitli yetişkin kök hücre popülasyonları bulunur ve bunlar dental kök hücreler olarak bilinir. Dental kök hücrelerin toplanması, saklanması ve tedaviye dahil edilmesi aşamalarında diş hekimleri aktif rol almaktadır. Bu çalışmada, farklı mesleki deneyime sahip diş hekimleri arasında dental kök hücrelerin varlığına ilişkin farkındalığın ve dental kök hücrelere ilişkin bilgi ve tutumlarının değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Bu çalışmada Mayıs-Haziran 2023 tarihinde Ankara ilinde farklı sektörlerde çalışan ve farklı mesleki deneyim sürelerine sahip 112 diş hekiminden oluşan toplam örneklem büyüklüğü seçildi. Diş hekimlerinin dental kök hücrelerine yönelik farkındalığını, bilgisini ve tutumunu değerlendirmek için kendi kendine uygulanan, elden teslim edilen, 22 soruluk bir anket kullanıldı. Sonuçlar ki-kare testi kullanılarak istatistiksel olarak analiz edildi.
Bulgular: Katılımcıların %96.4’ünün kök hücreler, %82.1’inin dental kök hücreler hakkında bilgisi vardı. Dental kök hücreler hakkında bilgi sahibi olanların %11.6’sı bilgi birikimini yeterli buluyordu. Katılımcıların %58’i Türkiye’de kök hücre bankalarının olduğunu biliyordu. Mesleki deneyimi <5 yıl olanların %83.7’si, 5-15 yıl olanların %85.4’ü ve >15 yıl olanların %72.7’si dental kök hücrelerin farkındaydı (p=0,428). Mesleki deneyimi <5 yıl olanların kök hücre bankalarından haberdar olma oranı anlamlı olarak daha düşüktü (p=0,016).
Sonuç: Bu çalışma diş hekimlerinin dental kök hücreler hakkında yüksek farkındalığa sahip oldukları ancak temel özellikleri hakkında yeterli bilgiye sahip olmadıklarını göstermektedir. Dental kök hücre kaynakları ve kök hücre bankaları hakkında lisans eğitimiyle başlayan ve mezuniyet sonrası eğitim programlarıyla devam eden bilgi içeriklerine diş hekimlerinin ihtiyacı vardır.

References

  • Chitroda P, Katti G, Attar N, Shahbaz S, Sreenivasarao G, Patil A. Stem cells in dentistry: A study regarding awareness of stem cells among dental professionals. Indian Journal of Dental Research. 2017;28(6):711-716.
  • Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences. 2000;97(25),13625-13630.
  • Huang YH, Yang JC, Wang CW, Lee SY. Dental Stem Cells and Tooth Banking for Regenerative Medicine. J Exp Clin Med. 2010;2(3):111-117.
  • Goswami M, Kumar G, Sharma S. “Dental Stem Cells”: Awareness, knowledge, and attitude of dental professionals—A cross-sectional study. Special Care in Dentistry. 2020;40(1):90-96.
  • Huang GTJ, Gronthos S, Shi S. Critical reviews in oral biology & medicine: Mesenchymal stem cells derived from dental tissues vs. those from other sources: Their biology and role in Regenerative Medicine. J Dent Res. 2009;88(9):792-806.
  • Derubeis AR, Cancedda R. Bone marrow stromal cells (BMSCs) in bone engineering: limitations and recent advances. Annals of biomedical engineering, 2004;32,160-165
  • Kwak KA, Lee SP, Yang JY, Park YS. Current perspectives regarding stem cell-based therapy for Alzheimer’s disease. Stem Cells Int. 2018;2018.
  • Lye JL, Soon LK, Ahmad WANW, Tan SC. Knowledge and attitude about stem cells and their application in medicine among nursing students in Universiti Sains Malaysia, Malaysia. The Malaysian journal of Medical Sciences: MJMS, 2015;22(4), 23
  • Deepika N, Devadiga S, Koshal N, Mittal S, Moidin T. Stem cells: A boon in dentistry. Journal of Dental Research and Review. 2015;2(1):47.
  • Vyas S, Vyas K, Satish M, Shende V, Srivastav R. Stem cells-The future of dentistry: A review. Journal of Indian Academy of Oral Medicine and Radiology. 2011;23(Suppl 1),S370-S372.
  • Mathur S, Chopra R, Pandit I, Srivastava N, Neeraj G. Stem cell research: applicability in dentistry. Int J Oral Maxillofac Implants. 2014;29(2):210-219.
  • Katge F, Shetty AJ, Rusawat B, Vamsi KC. Knowledge and attitude of Indian dentists regarding dental stem cells: A cross-sectional descriptive survey. Indian Journal of Dental Research. 2017;28(4):367-374.
  • Sede MA, Audu O, Azodo CC. Stem cells in Dentistry: Knowledge and attitude of Nigerian Dentists. BMC Oral Health. 2013;13(1).
  • Cord Blood Banking Regulation. Accessed March 29, 2024. https://www.mevzuat.gov.tr/mevzuat?MevzuatNo=8843&MevzuatTur=7&MevzuatTertip=5
  • Goomer P, Sidhu AK, Tuli P, Kansal S, Bansal K, Thakre GR. Awareness of stem cells & health implications of SHED found in pediatric dentition among Indian Population. Journal of International Oral Health. 2014;6(1),44.
  • Goyal A. Knowledge, awareness and attitude regarding stem cells among dental practitioners in Udaipur city, Rajasthan. International Journal of Advanced Research. 2015;677-684.
  • Abdulrazeq F, Kheirallah KA, Al-Mistarehi AH, Al Bashir S, ALQudah MA, Alzoubi A, et al. Effectiveness of interactive teaching intervention on medical students’ knowledge and attitudes toward stem cells, their therapeutic uses, and potential research applications. PeerJ, 2022;10,e12824.
  • Lipee D, Bhatt R, Bhatt A, Gurjar D, Dave L. Evaluating Awareness on Dental Pulp Stem Cells and its Applications amongst Graduating Dental Students of Ahmedabad and Gandhinagar District: A Cross-Sectional Survey. Human Biology Research Article Adv Hum Biol. 2014;4(3):54-59.
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Oral and Maxillofacial Surgery
Journal Section Araştırma Makalesi
Authors

Özge Demirdizen 0000-0002-0197-6668

Eda İzgi 0000-0003-2879-7798

Mehmet Barış Şimşek 0000-0002-8479-6709

Publication Date September 24, 2024
Submission Date April 4, 2024
Acceptance Date April 7, 2024
Published in Issue Year 2024 Volume: 13 Issue: 3

Cite

Vancouver Demirdizen Ö, İzgi E, Şimşek MB. Diş Hekimlerinin Dental Kök Hücrelere Dair Bilgi, Farkındalık ve Tutumlarının Değerlendirilmesi. ADO Klinik Bilimler Dergisi. 2024;13(3):426-34.