Abstract
Oral antikoagülan tedavide kullanılan
başlıca ilaçlar vitamin K antagonistleridir.Bu grubun başlıca
üyesi warfarin olup,tromboembolik olaylarda tedavi amacıyla
kullanılırken,aynı zamanda atriyal fibrilasyon ve diğer
kardiyavasküler hastalıklarda tromboemboliyi önlemek için de
kullanılmaktadır.Warfarin tedavisinin en önemli yan etkisi
kanamadır.Spontan intestinal intramural hematom ise bu ilaca bağlı
olarak ender görülen,akut karın tablosunu taklit eden bir
komplikasyondur.Warfarin kullanan karın ağrısı olan hastalarda
spontan intestinal intramural hematom ayırıcı tanıda
düşünülmelidir.Bu çalışmada spontan intestinal intramural
hematom nedeni ile non-operatif olarak takip edilen bir olguyu
sunarak nadir görülen bu durumu hatırlatmayı amaçladık.
References
- Levine MN, Raskob G, Beyth RJ, Kearon C, Schulman S. Hemorrhagic complications of anticoagulanttreatment. Chest 2004;126:287-310
- Tarim A, Yildirim S, Nursal TZ, Noyan T. Intraabdominal and intramural hemorrhage due to warfarin therapy. Turkish Journal of Trauma and Emergency Surgery 2003; 9: 50-3.
- Landefeld S, Beyth R. Anticoagulantrelated bleeding: Clinical epidemiology,prediction, and revention. Am J Med1993;95:315-28
- Abbas MA, Collins JM, Olden KW. Spontaneous intramural small-bowel hematoma: imaging findings and outcome. AJR Am J Roentgenol. 2002;179(6):1389-94.
- Uzun MA, Koksal N, Gunerhan Y, et al. Intestinal obstruction due to spontaneous intramural hematoma of the small intestine during warfarin use: a report of two cases. Eur J Emerg Med 2007; 14: 272-3.
- Polat C, Dervisoglu A, Güven H, ve ark. Anticoagulant-induced intramural intestinal hematoma. Am J Emerg Med 2003; 21:208-211
- Kar H, Peker Y, Cin N, Kahya MC, Koc O, Karabuga T, et al. İntra-abdominal hemorrhage due to uncontrolled warfarin therapy: two case reports.Marmara Medical Journal 2010; 23: 377-81.
- Hou SW, Chen CC, Chen KC, et al. Sonographic diagnosis of spontaneous intramural small bowel hematoma in a case of warfarin overdose. J Clin Ultrasound 2008; 36: 374-6.
- Akın T, Sedat Y, Tarık N, Turgut N. Warfarine bağlı gelişen karın içi barsak duvarı kanamaları. Ulusal Travma Dergisi 2003;9:50-53.
- Zengin K, Carkman S, Kilic I, Beken E, Eyuboglu E. Treatment approaches to rectus sheath hematoma. Ulus Travma Acil Cerrahi Dergisi 2007; 13(1): 55-9.
- Kılbaş Z, Harlak A, Ersöz N, Özerhan İH, Menteş Ö, Eryılmaz M. Warfarin toksisitesine bağlı nadir bir akut karın nedeni: Spontan intramural intestinal hematom. Ak Acil Tıp Derg 2009;4:43-45
- Altınkaya N, Parlakgumus A, Demir S, Alkan O,Yıldırım T. Small bowel obstruction caused by intramural hematoma secondary to warfarin therapy:A report of two cases. Turk J Gastroenterol 2011; 22: 199-202.
Abstract
The main drugs used in oral
anticoagulant therapy, are the vitamin K antagonists.The principal
member of this group is warfarin, used for treatment of
thromboembolic events,as well as atrial fibrillation and other
cardiovasculer events to prevent thromboembolic results.The most
important side of warfarin treatment is bleeding. Spontaneaus
intestinal intramural hematom is rare, depending on the drug.In
differential diagnosis acute abdomen must be reminded.In patients
using warfarin, with abdominal pain spontan intestinal intramural
hematom must be reminded in differential diagnosis.In this study we
aimed to remind this situation, in a nonoperative case with spontan
intestinal intramural hematoma.
References
- Levine MN, Raskob G, Beyth RJ, Kearon C, Schulman S. Hemorrhagic complications of anticoagulanttreatment. Chest 2004;126:287-310
- Tarim A, Yildirim S, Nursal TZ, Noyan T. Intraabdominal and intramural hemorrhage due to warfarin therapy. Turkish Journal of Trauma and Emergency Surgery 2003; 9: 50-3.
- Landefeld S, Beyth R. Anticoagulantrelated bleeding: Clinical epidemiology,prediction, and revention. Am J Med1993;95:315-28
- Abbas MA, Collins JM, Olden KW. Spontaneous intramural small-bowel hematoma: imaging findings and outcome. AJR Am J Roentgenol. 2002;179(6):1389-94.
- Uzun MA, Koksal N, Gunerhan Y, et al. Intestinal obstruction due to spontaneous intramural hematoma of the small intestine during warfarin use: a report of two cases. Eur J Emerg Med 2007; 14: 272-3.
- Polat C, Dervisoglu A, Güven H, ve ark. Anticoagulant-induced intramural intestinal hematoma. Am J Emerg Med 2003; 21:208-211
- Kar H, Peker Y, Cin N, Kahya MC, Koc O, Karabuga T, et al. İntra-abdominal hemorrhage due to uncontrolled warfarin therapy: two case reports.Marmara Medical Journal 2010; 23: 377-81.
- Hou SW, Chen CC, Chen KC, et al. Sonographic diagnosis of spontaneous intramural small bowel hematoma in a case of warfarin overdose. J Clin Ultrasound 2008; 36: 374-6.
- Akın T, Sedat Y, Tarık N, Turgut N. Warfarine bağlı gelişen karın içi barsak duvarı kanamaları. Ulusal Travma Dergisi 2003;9:50-53.
- Zengin K, Carkman S, Kilic I, Beken E, Eyuboglu E. Treatment approaches to rectus sheath hematoma. Ulus Travma Acil Cerrahi Dergisi 2007; 13(1): 55-9.
- Kılbaş Z, Harlak A, Ersöz N, Özerhan İH, Menteş Ö, Eryılmaz M. Warfarin toksisitesine bağlı nadir bir akut karın nedeni: Spontan intramural intestinal hematom. Ak Acil Tıp Derg 2009;4:43-45
- Altınkaya N, Parlakgumus A, Demir S, Alkan O,Yıldırım T. Small bowel obstruction caused by intramural hematoma secondary to warfarin therapy:A report of two cases. Turk J Gastroenterol 2011; 22: 199-202.
Details
| Journal Section | Case report |
|---|---|
| Authors | |
| Publication Date | December 1, 2017 |
| Submission Date | June 8, 2017 |
| Published in Issue | Year 2017 Volume: 50 Issue: 2 |
