YÜKSEK RAKIMDA YAŞAYAN BEHÇET HASTALARINDA HEMOTOKRİT YÜKSEKLİĞİNİN VASKÜLER TUTULUMA ETKİSİ

Hamit Küçük; Özlem Kudaş

doi:10.20492/aeahtd.661864

Research Article

YÜKSEK RAKIMDA YAŞAYAN BEHÇET HASTALARINDA HEMOTOKRİT YÜKSEKLİĞİNİN VASKÜLER TUTULUMA ETKİSİ

Year 2020, Volume: 53 Issue: 1, 25 - 28, 31.03.2020

Hamit Küçük , Özlem Kudaş

https://doi.org/10.20492/aeahtd.661864

Abstract

Amaç: Behçet hastalığı tanısıyla izlenen hastalarda deniz seviyesinden 1890 m de yaşamanın vasküler tutulum ve trombüs ile ilişkisi incelendi.
Materyal ve Metod: Yüksek akımda yaşamakta olan (ortalama 1890 metre) bir eğitim araştırma hastanesinde takip edilen Behçet hastalığı tanısı konulmuş olan hastalar ile ve 890 metrede yaşayan Behçet hastasının vasküler patoloji ve trombüs açısından klinik ve demografik verileri retrospektif olarak karşılaştırıldı.
Bulgular: Her iki grubunda yaş ortalaması ve cinsiyet dağılımı açısından istatiksel olarak anlamlı bir fark yoktu. Vasküler tutulum ve tromboembolik olaylar açısından her iki grupta benzer tutulum gözlendi.
Sonuç: Yüksek rakım nedeniyle oluşmuş olan hemotokrit yüksekliği Behçet hastalarında vaskuler tutulum ve trombus için ilave bir risk oluşturmamaktadır.

Keywords

Hemotokrit, behçet hastalığı, vaskülit, trombüs, yüksek rakım

References

1. G. Hatemi, Y. Yazici, H. Yazici. Behcet’ssyndrome. RheumDisClin North Am, 39 (2013), pp. 245-261
2. E. Kural-Seyahi, I. Fresko, N. Seyahi, et al.Thelong-termmortalityandmorbidity of Behcetsyndrome: a 2-decade outcomesurvey of 387 patientsfollowed at a dedicatedcenterMedicine, 82 (2003), pp. 60-76
3. Davatchi F, Shahram F, Chams-Davatchi C, Shams H, Nadji A, Akhlaghi M, Faezi T, Ghodsi Z, Larimi R, Ashofteh F, Abdollahi BS. Behcet's disease in Iran: analysis of 6500 cases. Int J Rheum Dis. 2010 Oct;13(4):367-73.
4. Chen Y, Cai JF, Lin CH, Guan JL. Demography of vascular Behcet's disease with different gender and age: an investigation with 166 Chinese patients. Orphanet J Rare Dis. 2019 Apr 29;14(1):88.
5. Saadoun D, Wechsler B, Desseaux K, Le Thi Huong D, Amoura Z, Resche-Rigon M, Cacoub P. Mortality in Behçet's disease. Arthritis Rheum. 2010 Sep;62(9):2806-12.
6. Hatemi G, Seyahi E, Fresko I, Talarico R, Hamuryudan V. Behçet's syndrome: a critical digest of the 2013-2014 literature. Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S112-22.
7. Yazıcı H, Seyahi E. Behçet syndrome: the vascular cluster. Turk J Med Sci. 2016 Nov 17;46(5):1277-1280.
8. Bahbahani H, Aljenaee K, Bella A.Polycythemiaverapresenting as acutemyocardialinfarction: An unusualpresentation. J SaudiHeartAssoc. 2015 Jan;27(1):57-60.
9. AnthonyLizarraga W, Dalia S, Reinert SE, Schiffman FJ.Venousthrombosis in patientswithchronicliverdisease.Blood CoagulFibrinolysis. 2010 Jul;21(5):431-5.
10. Fujimaki, T., Matsutani, M., Asai, A., Kohno, T., and Koike, M. Cerebral venous thrombosis due to high-altitude polycythemia: case report. J Neurosurg. 1986; 64: 148–150
11. Alibaz-Oner F, Karadeniz A, Ylmaz S, Balkarl A, Kimyon G, Yazc A, Çnar M, Ylmaz S, Yldz F, Bilge ŞY, Bilgin E, Coskun BN, Omma A, Çetin GY, Çağatay Y, Karaaslan Y, Sayarlioğlu M, Pehlivan Y, Kalyoncu U, Karadağ Ö, Kaşifoğlu T, Erken E, Pay S, Çefle A, Kisacik B, Onat AM, Çobankara V, Direskeneli H. Behçet disease with vascular involvement: effects of different therapeutic regimens on the incidence of new relapses. Medicine (Baltimore). 2015 Feb;94(6):e494.
12. Saito S, Tanaka SK. A case of cerebral sinus thrombosis developed during a high-altitude expedition to Gasherbrum I. Wilderness Environ Med. 2003 Winter;14(4):226-230.
13. Jha, S.K., Anand, A.C., Sharma, V., Kumar, N., and Adya, C.M. Stroke at high altitude: Indian experience. High Alt Med Biol. 2002; 3: 21–27
14. Dickinson, J., Heath, D., Gosney, J., and Williams, D. Altitude-related deaths in seven trekkers in the Himalayas. Thorax. 1983; 38: 646–656
15. Hull CM, Rajendran D, Fernandez Barnes A. Deep Vein Thrombosis and Pulmonary Embolism in a Mountain Guide: Awareness, Diagnostic Challenges, and Management Considerations at Altitude Wilderness Environ Med. 2016 Mar;27(1):100-6.
16. Gupta N, Ashraf MZ. Exposure to high altitude: a risk factor for venous thromboembolism? Semin Thromb Hemost. 2012 Mar;38(2):156-63.
17. Alibaz-Oner F, Direskeneli H. Management of vascular Behçet's disease. Int J Rheum Dis. 2019 Jan;22 Suppl 1:105-108.
18. HIRSJARVI E, VIHAVAINEN M, KOIKKALAINEN K. POLYCYTHEMIA IN CHRONIC RESPIRATORY ANOXIA. Ann Acad Sci Fenn A. 1964;106:1-13.
19. Dintenfass L. Elevation of blood viscosity, aggregation of red cells, haematocrit values and fibrinogen levels with cigarette smokers. Med J Aust. 1975 May 17;1(20):617-2
20. Garcia D, Erkan D. Diagnosis and Management of the Antiphospholipid Syndrome. N Engl J Med. 2018 May 24;378(21):2010-2021
21. Dautaj A, Krasi G, Bushati V, Precone V, Gheza M, Fioretti F, Sartori M, Costantini A, Benedetti S, Bertelli M. Hereditary thrombophilia. Acta Biomed. 2019 Sep 30;90(10-S):44-

Year 2020, Volume: 53 Issue: 1, 25 - 28, 31.03.2020

Hamit Küçük , Özlem Kudaş

https://doi.org/10.20492/aeahtd.661864

Abstract

References

1. G. Hatemi, Y. Yazici, H. Yazici. Behcet’ssyndrome. RheumDisClin North Am, 39 (2013), pp. 245-261
2. E. Kural-Seyahi, I. Fresko, N. Seyahi, et al.Thelong-termmortalityandmorbidity of Behcetsyndrome: a 2-decade outcomesurvey of 387 patientsfollowed at a dedicatedcenterMedicine, 82 (2003), pp. 60-76
3. Davatchi F, Shahram F, Chams-Davatchi C, Shams H, Nadji A, Akhlaghi M, Faezi T, Ghodsi Z, Larimi R, Ashofteh F, Abdollahi BS. Behcet's disease in Iran: analysis of 6500 cases. Int J Rheum Dis. 2010 Oct;13(4):367-73.
4. Chen Y, Cai JF, Lin CH, Guan JL. Demography of vascular Behcet's disease with different gender and age: an investigation with 166 Chinese patients. Orphanet J Rare Dis. 2019 Apr 29;14(1):88.
5. Saadoun D, Wechsler B, Desseaux K, Le Thi Huong D, Amoura Z, Resche-Rigon M, Cacoub P. Mortality in Behçet's disease. Arthritis Rheum. 2010 Sep;62(9):2806-12.
6. Hatemi G, Seyahi E, Fresko I, Talarico R, Hamuryudan V. Behçet's syndrome: a critical digest of the 2013-2014 literature. Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S112-22.
7. Yazıcı H, Seyahi E. Behçet syndrome: the vascular cluster. Turk J Med Sci. 2016 Nov 17;46(5):1277-1280.
8. Bahbahani H, Aljenaee K, Bella A.Polycythemiaverapresenting as acutemyocardialinfarction: An unusualpresentation. J SaudiHeartAssoc. 2015 Jan;27(1):57-60.
9. AnthonyLizarraga W, Dalia S, Reinert SE, Schiffman FJ.Venousthrombosis in patientswithchronicliverdisease.Blood CoagulFibrinolysis. 2010 Jul;21(5):431-5.
10. Fujimaki, T., Matsutani, M., Asai, A., Kohno, T., and Koike, M. Cerebral venous thrombosis due to high-altitude polycythemia: case report. J Neurosurg. 1986; 64: 148–150
11. Alibaz-Oner F, Karadeniz A, Ylmaz S, Balkarl A, Kimyon G, Yazc A, Çnar M, Ylmaz S, Yldz F, Bilge ŞY, Bilgin E, Coskun BN, Omma A, Çetin GY, Çağatay Y, Karaaslan Y, Sayarlioğlu M, Pehlivan Y, Kalyoncu U, Karadağ Ö, Kaşifoğlu T, Erken E, Pay S, Çefle A, Kisacik B, Onat AM, Çobankara V, Direskeneli H. Behçet disease with vascular involvement: effects of different therapeutic regimens on the incidence of new relapses. Medicine (Baltimore). 2015 Feb;94(6):e494.
12. Saito S, Tanaka SK. A case of cerebral sinus thrombosis developed during a high-altitude expedition to Gasherbrum I. Wilderness Environ Med. 2003 Winter;14(4):226-230.
13. Jha, S.K., Anand, A.C., Sharma, V., Kumar, N., and Adya, C.M. Stroke at high altitude: Indian experience. High Alt Med Biol. 2002; 3: 21–27
14. Dickinson, J., Heath, D., Gosney, J., and Williams, D. Altitude-related deaths in seven trekkers in the Himalayas. Thorax. 1983; 38: 646–656
15. Hull CM, Rajendran D, Fernandez Barnes A. Deep Vein Thrombosis and Pulmonary Embolism in a Mountain Guide: Awareness, Diagnostic Challenges, and Management Considerations at Altitude Wilderness Environ Med. 2016 Mar;27(1):100-6.
16. Gupta N, Ashraf MZ. Exposure to high altitude: a risk factor for venous thromboembolism? Semin Thromb Hemost. 2012 Mar;38(2):156-63.
17. Alibaz-Oner F, Direskeneli H. Management of vascular Behçet's disease. Int J Rheum Dis. 2019 Jan;22 Suppl 1:105-108.
18. HIRSJARVI E, VIHAVAINEN M, KOIKKALAINEN K. POLYCYTHEMIA IN CHRONIC RESPIRATORY ANOXIA. Ann Acad Sci Fenn A. 1964;106:1-13.
19. Dintenfass L. Elevation of blood viscosity, aggregation of red cells, haematocrit values and fibrinogen levels with cigarette smokers. Med J Aust. 1975 May 17;1(20):617-2
20. Garcia D, Erkan D. Diagnosis and Management of the Antiphospholipid Syndrome. N Engl J Med. 2018 May 24;378(21):2010-2021
21. Dautaj A, Krasi G, Bushati V, Precone V, Gheza M, Fioretti F, Sartori M, Costantini A, Benedetti S, Bertelli M. Hereditary thrombophilia. Acta Biomed. 2019 Sep 30;90(10-S):44-

There are 21 citations in total.

Details

Primary Language	Turkish
Subjects	Health Care Administration
Journal Section	Original research article
Authors	Hamit Küçük Özlem Kudaş
Publication Date	March 31, 2020
Submission Date	December 24, 2019
Published in Issue	Year 2020 Volume: 53 Issue: 1

Cite

AMA	Küçük H, Kudaş Ö. YÜKSEK RAKIMDA YAŞAYAN BEHÇET HASTALARINDA HEMOTOKRİT YÜKSEKLİĞİNİN VASKÜLER TUTULUMA ETKİSİ. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. March 2020;53(1):25-28. doi:10.20492/aeahtd.661864

Article Files

Full Text