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PANKREAS KANSERİ

Year 2021, Volume: 54 Issue: 1, 59 - 65, 27.04.2021
https://doi.org/10.20492/aeahtd.806164

Abstract

Pankreas kanseri, dünyada yaygın kanser çeşitleri arasında 14. sırada, kansere bağlı mortalite sıralamasında 7. sırada yer almaktadır. İnsidansı giderek artmakta olup erken tanı ve tedavinin önemi büyüktür. Agresif yapısından dolayı hızlı yayılır ve ölümcül sonuçlar doğurur. Zamanında tanı konulmuş hastalarda küratif tedavi şansı cerrahi rezeksiyon (Whipple ameliyatı) ile sağlanabilir. Tedavi sonrası nükslerin görülmesi ne yazık ki sürpriz değildir. Değiştirilebilir risk faktörleri için gerekli önlemler alınmalı, riskli grupta yer alan kişilere tarama çalışmaları yapılmalıdır. Erken tanı ve tedavi için gerekli hassasiyet gösterilmesi önem arz etmektedir.

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References

  • Wolfgang CL, Herman JM, Laheru DA, et al. Recent progress in pancreatic cancer. CA Cancer J Clin. 2013; 63:318-48.
  • Modi B, Shires GT. Pancreatic cancer, cystic pancreatic neoplasms, and other nonendocrine pancreatic tumor. In: Feldman M, Friedman L, Brandt L; eds. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 11th ed. Chapter 60, Philadelphia: Elsevier; 2020. p.947-965.
  • McGuigan A, Kelly P, Turkington RC, et al. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes.World Journal Of Gastroenterology 2018; 24: 4846–61.
  • Daniel D. Von Hoff. Pancreatic Cancer: Harrison’s Principles of Internal Medicine 20th ed. Chapter 79, Mc Graw Hill Education: 2018; 591-596.
  • Fernandez-del Castillo C. Clinical maniffestations, diagnosis and staging of exocrine pancreatic cancer. In: Tanabe K, Howell D. eds. Up to Date, Feb. 2020, Erişim Tarihi Ağustos 2020.
  • Ilic M, Ilic I. Epidemiology of pancreatic cancer. World J Gastroenterol. 2016; 22:9694–705
  • International Agency for Research on Cancer, World Health Organization. Global Cancer Observatory 2018.
  • T.C. Sağlık Bakanlığı Sağlık İstastistikleri Yıllığı 2018: 43.
  • Göral V. Pankreas kanseri: patogenez ve tanı. Güncel Gastroenteroloji Dergisi 2014; 18/4.
  • Longnecker D. Pathology of exocrine pancreas. In: Golberg RM eds. Up to Date, Oct 22, 2019. Erişim Tarihi: Ağustos 2020.
  • Lowenfels AB, Maisonneuve P. Epidemiology and risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterology. 2006; 20: 197-209.
  • Çetin Ş, Dede İ. Prognostic factors in pancreatic cancer. Med J SDU. 2019; 26:30-4.
  • Şahin M, Cindoruk M. Endosonografi yapılan pankreatik kitle lezyonlarının cerrahi ve ince iğne aspirasyon biyopsi verilerinin patolojik sonuçlar ile analizi: 6 yıllık deneyim. Pamukkale Tıp Dergisi. 2019;12:1-6.
  • Tandoğan G. Lokal ileri rezeke edilemeyen pankreas kanserinde kemoterapi ve kemoradyoterapi tedavilerinin etkinliklerinin karşılaştırılması. Uludağ Üniversitesi İç Hastalıkları ABD. Tıpta Uzmanlık Tezi, Bursa, Türkiye, 2012.
  • Gress FG, Hawes RH, Savides TJ, et al. Role of EUS in the preoperative staging of pancreatic cancer: A large single-center experience. Gastrointest Endosc. 1999; 50:786-91.
  • Du T, Bill KA, Ford J, et al. The diagnosis and staging of pancreatic cancer: A comparison of endoscopic ultrasound and Computed Tomography with pancreas protocol. Am J Surg. 2018: 215; 472-5.
  • Yarandi S, Runge T, Wang L et al. Increased incidance of benign pancreatic pathology following pancreaticoduodenectomy for presumed malignancy over 10 years despite use of endoscopic ultrasound. Diagnostic and Therapeutic Endoscopy Volume. 2014; 1-6.
  • Bose D, Katz MHG, Fleming JB. Pancreatic Adenocarcinoma. In: Feig BW, Ching CD eds. The MD Anderson Surgical Oncology Handbook. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2012. p472-87.
  • Rooij T, Klompmaker S, Hilal MA et al. Laparoscopic pancreatic surgery for benign and malignant disease. Nature Reviews Gastroenterology & Hepatology.2016:13; 227-238.

PANCREAS CANCER

Year 2021, Volume: 54 Issue: 1, 59 - 65, 27.04.2021
https://doi.org/10.20492/aeahtd.806164

Abstract

Pancreatic cancer is ranked as the 14th most common cancer and the 7th highest cause of cancer mortality in the world. Its incidence is gradually increasing and early diagnosis and treatment is of great importance. Due to its aggressive nature, it spreads rapidly and has fatal consequences. In patients diagnosed in time, the chance of curative treatment can be provided by surgical resection (Whipple operation). Unfortunately, recurrence after treatment is not a suprise. Necessary precautions should be taken for modifiable risk factors and screening studies should be carried out for people in the risky group. It is important to show the necessary sensitivity for early diagnosis and treatment.

Project Number

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References

  • Wolfgang CL, Herman JM, Laheru DA, et al. Recent progress in pancreatic cancer. CA Cancer J Clin. 2013; 63:318-48.
  • Modi B, Shires GT. Pancreatic cancer, cystic pancreatic neoplasms, and other nonendocrine pancreatic tumor. In: Feldman M, Friedman L, Brandt L; eds. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 11th ed. Chapter 60, Philadelphia: Elsevier; 2020. p.947-965.
  • McGuigan A, Kelly P, Turkington RC, et al. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes.World Journal Of Gastroenterology 2018; 24: 4846–61.
  • Daniel D. Von Hoff. Pancreatic Cancer: Harrison’s Principles of Internal Medicine 20th ed. Chapter 79, Mc Graw Hill Education: 2018; 591-596.
  • Fernandez-del Castillo C. Clinical maniffestations, diagnosis and staging of exocrine pancreatic cancer. In: Tanabe K, Howell D. eds. Up to Date, Feb. 2020, Erişim Tarihi Ağustos 2020.
  • Ilic M, Ilic I. Epidemiology of pancreatic cancer. World J Gastroenterol. 2016; 22:9694–705
  • International Agency for Research on Cancer, World Health Organization. Global Cancer Observatory 2018.
  • T.C. Sağlık Bakanlığı Sağlık İstastistikleri Yıllığı 2018: 43.
  • Göral V. Pankreas kanseri: patogenez ve tanı. Güncel Gastroenteroloji Dergisi 2014; 18/4.
  • Longnecker D. Pathology of exocrine pancreas. In: Golberg RM eds. Up to Date, Oct 22, 2019. Erişim Tarihi: Ağustos 2020.
  • Lowenfels AB, Maisonneuve P. Epidemiology and risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterology. 2006; 20: 197-209.
  • Çetin Ş, Dede İ. Prognostic factors in pancreatic cancer. Med J SDU. 2019; 26:30-4.
  • Şahin M, Cindoruk M. Endosonografi yapılan pankreatik kitle lezyonlarının cerrahi ve ince iğne aspirasyon biyopsi verilerinin patolojik sonuçlar ile analizi: 6 yıllık deneyim. Pamukkale Tıp Dergisi. 2019;12:1-6.
  • Tandoğan G. Lokal ileri rezeke edilemeyen pankreas kanserinde kemoterapi ve kemoradyoterapi tedavilerinin etkinliklerinin karşılaştırılması. Uludağ Üniversitesi İç Hastalıkları ABD. Tıpta Uzmanlık Tezi, Bursa, Türkiye, 2012.
  • Gress FG, Hawes RH, Savides TJ, et al. Role of EUS in the preoperative staging of pancreatic cancer: A large single-center experience. Gastrointest Endosc. 1999; 50:786-91.
  • Du T, Bill KA, Ford J, et al. The diagnosis and staging of pancreatic cancer: A comparison of endoscopic ultrasound and Computed Tomography with pancreas protocol. Am J Surg. 2018: 215; 472-5.
  • Yarandi S, Runge T, Wang L et al. Increased incidance of benign pancreatic pathology following pancreaticoduodenectomy for presumed malignancy over 10 years despite use of endoscopic ultrasound. Diagnostic and Therapeutic Endoscopy Volume. 2014; 1-6.
  • Bose D, Katz MHG, Fleming JB. Pancreatic Adenocarcinoma. In: Feig BW, Ching CD eds. The MD Anderson Surgical Oncology Handbook. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2012. p472-87.
  • Rooij T, Klompmaker S, Hilal MA et al. Laparoscopic pancreatic surgery for benign and malignant disease. Nature Reviews Gastroenterology & Hepatology.2016:13; 227-238.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Review
Authors

Pınar Koçatakan 0000-0002-5070-1150

Hilmi Ataseven 0000-0001-5458-509X

Project Number -
Publication Date April 27, 2021
Submission Date October 5, 2020
Published in Issue Year 2021 Volume: 54 Issue: 1

Cite

AMA Koçatakan P, Ataseven H. PANKREAS KANSERİ. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. April 2021;54(1):59-65. doi:10.20492/aeahtd.806164