Evaluation of Corneal Endothelium by Specular Microscopy in Pseudoexfoliation Syndrome

Year 2021, Volume: 5 Issue: 3, 202 - 206, 22.12.2021

Murat Serkan Songur , Seray Aslan , Hasan Ali Bayhan

https://doi.org/10.46332/aemj.926817

Abstract

Purpose: To evaluate the corneal endothelium of patients with pseudoexfoliation syndrome (PES) by specular microscopy (SM).

Materials and Methods: In this prospective controlled study, two groups were formed, namely the PES group and the control group. The right eyes of 50 patients were diagnosed with pseudoexfoliation material by slit lamp biomicroscopy performed in the ophthalmology outpatient clinic, and the right eyes of 50 patients in control group without any health problems were examined.

Results: There was no difference between the control and patient groups in terms of gender and age distribution (p>0.005). Statistically, no difference was found between the groups in corneal thickness (p=0.105). However, coefficient of variation, corneal endothelial cell density and hexagonal cell ratio were found to be statistically significant between the two groups.

Conclusion: Serious morphological changes occur in the corneal endothelium in patients with PES. Because of these changes in the corneal endothelium, it is recommended to perform specular microscopy measurement before cataract surgery of all patients who have PES detected in their examination.

Keywords

Pseudoexfoliation syndrome, specular microscopy, corneal endothelium

Psödoeksfoliasyon Sendromunda Kornea Endotelinin Speküler Mikroskopi ile Değerlendirilmesi

Abstract

Amaç: Psödoeksfoliasyon sendromu (PES) olan hastaların kornea endotelini speküler mikroskopi (SM) ile değerlendirmektir.

Araçlar ve Yöntem: Bu prospektif kontrollü çalışmada, PES ve kontrol grubu olmak üzere iki grup oluşturuldu. Göz hastalıkları polikliniğinde yapılan yarık lamba biyomikroskopisiyle psödoeksfoliasyon materyali tespit edilerek tanı konulan 50 hastanın sağ gözü ve herhangi bir sağlık problemi olmayan 50 kontrol grubunun sağ gözü incelenmiştir.

Bulgular: Kontrol ve hasta grubunun cinsiyet ve yaş dağılımı açısından birbirinden farkı yoktu (p>0.005). İstatiksel olarak kornea kalınlığında, gruplar arasında fark bulunamadı (p=0.105). Ancak varyasyon katsayısı, kornea endotel hücre yoğunluğu ve heksagonal hücre oranında PES’li grupla PES olmayan grup arasında istatiksel olarak anlamlı düzeyde fark olduğu tespit edildi.

Sonuç: PES tespit edilen hastalarda kornea endotelinde ciddi morfolojik değişiklikler meydana gelmektedir. Kornea endotelinde meydana gelen bu değişimler nedeniyle, yapılan muayenesinde PES tespit edilen tüm hastaların, katarakt ameliyatı öncesinde speküler mikroskopi ile incelenmesi önerilmektedir.

Keywords

Psödoeksfoliasyon sendromu, speküler mikroskopi, kornea endoteli

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