Akut fosfat nefropatisi: İki olgu sunumu ve literatürün gözden geçirilmesi

Year 2023, , 41 - 44, 30.04.2023

Gamze Ergün Sezer Arzu Özdemir Ahmet Burak Dirim Erdem Baran Mürvet Yılmaz

https://doi.org/10.17941/agd.1276934

Abstract

Fosfat nefropatisi; fosfat kristallerinin renal tübülleri etkilemesiyle oluşan önce akut, sonrasında kronik böbrek hasarı ile seyreden bir klinik tablodur. Kolonoskopi birçok endikasyonla sık olarak kullanılan bir yöntemdir. İşlem öncesinde hazırlık amaçlı kullanılan oral fosfat içerikli pürgatifler bu tablonun gelişimine yol açmaktadır. Nefropati gelişme riski yüksek olan gruplarda, fosfat içermeyen pürgatiflerin kullanılması önerilmektedir. Fosfat nefropatisi tedavisinde temel yaklaşım hasarın gelişimini önlemektir. Biz bu yazımızda, oral sodyum fosfat ile kolonoskopi yapılan ve işlem sonrası fosfat nefropatisi ile uyumlu akut böbrek hasarı gelişen iki vakayı sunmayı amaçladık.

Keywords

Fosfat nefropatisi, kolonoskopi, pürgatif

Acute phosphate nephropathy: Two case reports and review of the literature

Abstract

Phosphate nephropathy is a clinical picture that occurs with the effect of phosphate crystals on the renal tubules, which first progresses with acute and then chronic kidney damage. Colonoscopy is a method for direct examination of the colon performed with various indications. Oral phosphate-containing purgatives used for preparatory purposes before this procedure lead to the development of this disease. In groups with a high risk of developing nephropathy, phosphate-free purgatives are recommended during the preparation for the colonoscopy. The principal treatment for phosphate nephropathy is to prevent the development of damage. In this article, we aimed to present two cases of phosphate nephropathy who underwent colonoscopy for different indications and that oral phosphate was used during the preparation for the procedure.

Keywords

Phosphate nephropathy, colonoscopy, purgative

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