The Use of Therapeutic Interventions for Improving Balance and Gait in People with Multiple Sclerosis: A Systematic Review of Studies Conducted in Turkey

Year 2023, Volume: 7 Issue: 3, 235 - 251, 24.12.2023

Meryem Koçaslan Toran , İsmail Toyğar , Gizem Yağmur Yalçın

Abstract

This systematic review aimed to evaluate the effectiveness of therapeutic interventions used in the treatment of balance and gait in multiple sclerosis by reviewing studies conducted in Turkey. Studies were included according to the following eligibility criteria: Population, Multiple Sclerosis patients; Intervention, non-pharmacological therapeutic interventions for balance and gait; Comparison, usual intervention and no intervention/no special balance intervention; Outcome, balance and gait clinical scales; Study design, randomized controlled trials. A literature search was conducted in CENTRAL, MEDLINE/PubMed, EMBASE, ClinicalTrials.gov, TR Index for studies published between January 2013 and August 2023. The methodological quality of the included studies was assessed by the Quality Checklist for Randomized Controlled Trials published by the Joanna Briggs Institute. A total of 1023 participants (n) were included in this review. The average sample size per study was 37.88± 16.73. While 78% of the studies reported that the interventions they applied had a positive effect on walking and recovery outcomes in MS, 22% of the studies reported no significant superiority in balance and walking outcomes. The evidence showed that although a wide range of therapeutic interventions are available for balance and gait in people with MS, there is a serious lack of high-quality evidence demonstrating the effectiveness of these modalities.

Keywords

gait, multiple sclerosis, Postural balance, Therapeutic

Multipl Sklerozlu Kişilerde Denge ve Yürüyüşü İyileştirmek İçin Terapötik Müdahalelerin Kullanımı: Türkiye'de Yapılan Çalışmaların Sistematik Derlemesi

Abstract

Bu sistematik derleme, Türkiye'de yapılan çalışmaları gözden geçirerek multipl sklerozda denge ve yürüme tedavisinde kullanılan terapötik müdahalelerin etkinliğini değerlendirmeyi amaçlamaktadır. Çalışmalar aşağıdaki uygunluk kriterlerine göre dahil edilmiştir: Popülasyon, Multipl Skleroz hastaları; Müdahale, denge ve yürüyüş için farmakolojik olmayan terapötik müdahaleler; Karşılaştırma, olağan müdahale ve müdahale yok/özel denge müdahalesi yok; Sonuç, denge ve yürüyüş klinik ölçekleri; Çalışma tasarımı, randomize kontrollü çalışmalar. Ocak 2013 ile Ağustos 2023 tarihleri arasında yayınlanan çalışmalar için CENTRAL, MEDLINE/PubMed, EMBASE, ClinicalTrials.gov, TR Dizin'de literatür taraması yapılmıştır. Dahil edilen çalışmaların metodolojik kalitesi Joanna Briggs Enstitüsü tarafından yayınlanan Randomize Kontrollü Çalışmalar için Kalite Kontrol Listesi ile değerlendirilmiştir. Bu incelemeye toplam 1023 katılımcı (n) dahil edilmiştir. Çalışma başına ortalama örneklem büyüklüğü 37.88± 16.73'tür. Çalışmaların %78'i uyguladıkları müdahalelerin MS'te yürüme ve iyileşme sonuçlarına olumlu etkisinin olduğunu bildirirken, çalışmaların %22'si ise denge ve yürüme sonuçlarında anlamlı bir üstünlük olmadığını bildirmiştir. Bu inceleme sonucunda bulunan kanıtlar, MS'li kişilerde denge ve yürüme için çok çeşitli terapötik müdahalelerin mevcut olmasına rağmen, bu yöntemlerin etkinliğini gösteren yüksek kaliteli kanıtların ciddi şekilde eksik olduğunu göstermiştir.

Keywords

Duruş dengesi, yürüyüş biçimi, multipl skleroz, tedavi ediciler

Ethical Statement

The current review is a systematic review. Ethics committee is not necessary.

Supporting Institution

This study has not been financed by any institutional organization.

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