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Sonografide 20-24 Hafta Arasındaki Fetüslerde Üç Büyük Damarın Referans Çapları

Year 2023, Volume: 9 Issue: 3, 241 - 246, 01.09.2023
https://doi.org/10.53394/akd.1009966

Abstract

Amaç
Fetal kardiak anatomiyi değerlendirmek ve Türk popülasyonunda 20-24 hafta arasındaki fetüslerde üç ana damar [Pulmoner arter (PA), aorta, vena kava süperior (VKS)] çaplarının referans değerlerini saptamak.
Yöntemler
Mayıs 2009-Ağustos 2012 tarihleri arasında Radyoloji Bölümünde değerlendirilen gebelere fetal kardiyak büyük damarların nomogramlarının elde edilmesi için sonografik tarama yapıldı. Kalbin dört odacık görünümüne ek olarak kardiyak aks, boyut ve üç büyük damar değerlendirildi. Olgular postnatal olarak ekokardiyografi ve klinik değerlendirme ile takip edildi. Postnatal değerlendirme sonuçları temel alınarak 20-24. gebelik haftalarında yapılan sonografik taramanın duyarlılığı ve özgüllüğü hesaplandı. Ayrıca konjenital kalp hastalığı sıklığı araştırıldı. Her gebelik haftası için ortalama damar çapı hesaplanarak nomogramlar elde edildi.
Bulgular
Çalışma kapsamında toplam 371 fetüs değerlendirildi. Ortalama gebelik yaşı 29.2±5.2 yıldı. PA, aorta ve VKS ortalama çapları sırasıyla 4.28±0.51 mm, 3.70±0.54 mm ve 2.45±0.45 mm olarak bulundu. PA/aort oranı 1.17±0.14 idi. PA, aort ve VKS'nin ortalama çaplarının 20 ila 24 gebelik haftaları arasında kademeli olarak arttığı gözlendi (p değerleri 0.001, 0.007 ve 0.001). Sonografik olarak antenatal dönemde beş olguda kardiyak anomali (Fallot tetralojisi, tek atriyum tek ventrikül anomalisi, ASD, normalden geniş PA, normalden geniş aorta) tespit edildi. Beş vakadan üçünün tanısı doğum sonrası dönemde pediatrik kardiyologlar tarafından yapılan fetal ekokardiyografi ile doğrulandı.
Sonuçlar
Bu çalışma, 20-24 gestasyon haftasındaki fetüslerde üç büyük damar çapı için Türk popülasyonuna ait referans değerleri sunmaktadır. Ulusal verilerimizin ülkemizden yapılacak çalışmalara kaynak olacağını düşünmekteyiz.

Supporting Institution

Akdeniz Üniversitesi Bilimsel Araştırma Projeleri

Project Number

2011.04.0103.030

References

  • Van Nisselrooij AEL, Teunissen AKK, Clur SA, Rozendaal L, Pajkrt E, Linskens IH, Rammeloo L, van Lith JMM, Blom NA, Haak MC. Why are congenital heart defects being missed? Ultrasound Obstet Gynecol. 2020 Jun;55(6):747-757.
  • International Society of Ultrasound in Obstetrics and Gynecology, Carvalho JS, Allan LD, Chaoui R, at al. ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart. Ultrasound Obstet Gynecol. 2013;41:348-359.
  • Garne E, Loane M, Dolk H, De Vigan C, Scarano G, Tucker D, Stoll C, Gener B, Pierini A, Nelen V, Rösch C, Gillerot Y, Feijoo M, Tincheva R, Queisser-Luft A, Addor MC, Mosquera C, Gatt M, Barisic I. Prenatal diagnosis of severe structural congenital malformations in Europe. Ultrasound Obstet Gynecol. 2005 Jan;25(1):6-11.
  • American College of Radiology Guidelines and Standards Committee. ACR-ACOG-AIUM-SRU practice parameter for the performance of obstetrical ultrasound. Am Coll Radiol 2013;1–14.
  • American Institute of Ultrasound in Medicine. AIUM practice guideline for the performance of fetal echocardiography. J Ultrasound Med. 2013;32:1067-1082.
  • Garne E, Stoll C, Clementi M; Euroscan Group. Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries. Ultrasound Obstet Gynecol. 2001;17:386-391.
  • Wigton TR, Sabbagha RE, Tamura RK, Cohen L, Minogue JP, Strasburger JF. Sonographic diagnosis of congenital heart disease: comparison between the four-chamber view and multiple cardiac views. Obstet Gynecol. 1993;82:219-224.
  • Benacerraf BR. Sonographic detection of fetal anomalies of the aortic and pulmonary arteries: value of four-chamber view vs direct images. AJR Am J Roentgenol. 1994;163:1483-1489.
  • Bromley B, Estroff JA, Sanders SP, Parad R, Roberts D, Frigoletto FD Jr, Benacerraf BR. Fetal echocardiography: accuracy and limitations in a population at high and low risk for heart defects. Am J Obstet Gynecol. 1992 May;166(5):1473-81.
  • Yoo SJ, Lee YH, Kim ES, Ryu HM, Kim MY, Choi HK, Cho KS, Kim A. Three-vessel view of the fetal upper mediastinum: an easy means of detecting abnormalities of the ventricular outflow tracts and great arteries during obstetric screening. Ultrasound Obstet Gynecol. 1997 Mar;9(3):173-82.
  • Wong SF, Ward C, Lee-Tannock A, Le S, Chan FY. Pulmonary artery/aorta ratio in simple screening for fetal outflow tract abnormalities during the second trimester. Ultrasound Obstet Gynecol. 2007;30:275-280.
  • Kenny JF, Plappert T, Doubilet P, Saltzman DH, Cartier M, Zollars L, Leatherman GF, St John Sutton MG. Changes in intracardiac blood flow velocities and right and left ventricular stroke volumes with gestational age in the normal human fetus: a prospective Doppler echocardiographic study. Circulation. 1986 Dec;74(6):1208-16.
  • Cartier MS, Davidoff A, Warneke LA, Hirsh MP, Bannon S, Sutton MS, Doubilet PM. The normal diameter of the fetal aorta and pulmonary artery: echocardiographic evaluation in utero. AJR Am J Roentgenol. 1987 Nov;149(5):1003-7.
  • Achiron R, Golan-Porat N, Gabbay U, Rotstein Z, Heggesh J, Mashiach S, Lipitz S. In utero ultrasonographic measurements of fetal aortic and pulmonary artery diameters during the first half of gestation. Ultrasound Obstet Gynecol. 1998 Mar;11(3):180-4.
  • Zalel Y, Wiener Y, Gamzu R, Herman A, Schiff E, Achiron R. The three-vessel and tracheal view of the fetal heart: an in utero sonographic evaluation. Prenat Diagn. 2004;24:174-178.
  • Hautala J, Gissler M, Ritvanen A, Tekay A, Pitkänen-Argillander O, Stefanovic V, Sarkola T, Helle E, Pihkala J, Pätilä T, Mattila IP, Jokinen E, Räsänen J, Ojala T. The implementation of a nationwide anomaly screening programme improves prenatal detection of major cardiac defects: an 11-year national population-based cohort study. BJOG. 2019 Jun;126(7):864-873.
  • Itsukaichi M, Serikawa T, Yoshihara K, Suzuki H, Haino K, Yamaguchi M, Enomoto T; Niigata Fetal Cardiac Screening Study Group, Takakuwa K. Effectiveness of fetal cardiac screening for congenital heart disease using a combination of the four-chamber view and three-vessel view during the second trimester scan. J Obstet Gynaecol Res. 2018 Jan;44(1):49-53..

The reference diameters of the three great vessels in the fetuses between 20-24 weeks by sonography

Year 2023, Volume: 9 Issue: 3, 241 - 246, 01.09.2023
https://doi.org/10.53394/akd.1009966

Abstract

Objective:
We aimed to obtain reference values of three major vessels [Pulmonary artery (PA), aorta, vena cava superior (SVC)] diameters in fetuses between 20-24 weeks of gestation in the Turkish population and to evaluate the fetal heart anatomy.
Methods:
Between May 2009 and August 2012, pregnant women who evaluated in the Radiology Department were scanned by sonography in order to obtain fetal cardiac nomograms of the great vessels. Cardiac axis, size and three great vessels in addition to the four chamber view of the heart were evaluated. The cases were followed up postnatally with echocardiography and clinical evaluation. We calculated both the sensitivity and specificity of sonographic screening at the 20-24nd gestational weeks. Also, we found the frequency of congenital cardiac disease. Nomograms were obtained by calculating average vascular diameter for each gestational week.
Results:
A total of 371 fetuses evaluated in the sudy. The mean gestational age was 29.2±5.2. The mean diameters of PA, aorta and SVC were found 4.28±0.51 mm, 3.70±0.54 mm, 2.45±0.45 mm, respectively. The ratio of PA/aorta was 1.17±0.14. The mean diameters of PA, aorta and SVC were increasing gradually between 20 and 24 gestational weeks (p values 0.001, 0.007 and 0.001; repeated measures ANOVA). In five cases a cardiac anomaly was detected (tetralogy of Fallot, one atrium one ventricle anomaly, ASD, PA wider than normal, aorta wider than normal,) sonographically. Of these five, three cases were confirmed by postnatal fetal echocardiography performed by pediatric cardiologists.
Concluions:
This study represents the reference values for diameters of three great vessels of fetuses between 20 and 24 weeks in the Turkish population. Our national data will be a source for studies from our country.

Project Number

2011.04.0103.030

References

  • Van Nisselrooij AEL, Teunissen AKK, Clur SA, Rozendaal L, Pajkrt E, Linskens IH, Rammeloo L, van Lith JMM, Blom NA, Haak MC. Why are congenital heart defects being missed? Ultrasound Obstet Gynecol. 2020 Jun;55(6):747-757.
  • International Society of Ultrasound in Obstetrics and Gynecology, Carvalho JS, Allan LD, Chaoui R, at al. ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart. Ultrasound Obstet Gynecol. 2013;41:348-359.
  • Garne E, Loane M, Dolk H, De Vigan C, Scarano G, Tucker D, Stoll C, Gener B, Pierini A, Nelen V, Rösch C, Gillerot Y, Feijoo M, Tincheva R, Queisser-Luft A, Addor MC, Mosquera C, Gatt M, Barisic I. Prenatal diagnosis of severe structural congenital malformations in Europe. Ultrasound Obstet Gynecol. 2005 Jan;25(1):6-11.
  • American College of Radiology Guidelines and Standards Committee. ACR-ACOG-AIUM-SRU practice parameter for the performance of obstetrical ultrasound. Am Coll Radiol 2013;1–14.
  • American Institute of Ultrasound in Medicine. AIUM practice guideline for the performance of fetal echocardiography. J Ultrasound Med. 2013;32:1067-1082.
  • Garne E, Stoll C, Clementi M; Euroscan Group. Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries. Ultrasound Obstet Gynecol. 2001;17:386-391.
  • Wigton TR, Sabbagha RE, Tamura RK, Cohen L, Minogue JP, Strasburger JF. Sonographic diagnosis of congenital heart disease: comparison between the four-chamber view and multiple cardiac views. Obstet Gynecol. 1993;82:219-224.
  • Benacerraf BR. Sonographic detection of fetal anomalies of the aortic and pulmonary arteries: value of four-chamber view vs direct images. AJR Am J Roentgenol. 1994;163:1483-1489.
  • Bromley B, Estroff JA, Sanders SP, Parad R, Roberts D, Frigoletto FD Jr, Benacerraf BR. Fetal echocardiography: accuracy and limitations in a population at high and low risk for heart defects. Am J Obstet Gynecol. 1992 May;166(5):1473-81.
  • Yoo SJ, Lee YH, Kim ES, Ryu HM, Kim MY, Choi HK, Cho KS, Kim A. Three-vessel view of the fetal upper mediastinum: an easy means of detecting abnormalities of the ventricular outflow tracts and great arteries during obstetric screening. Ultrasound Obstet Gynecol. 1997 Mar;9(3):173-82.
  • Wong SF, Ward C, Lee-Tannock A, Le S, Chan FY. Pulmonary artery/aorta ratio in simple screening for fetal outflow tract abnormalities during the second trimester. Ultrasound Obstet Gynecol. 2007;30:275-280.
  • Kenny JF, Plappert T, Doubilet P, Saltzman DH, Cartier M, Zollars L, Leatherman GF, St John Sutton MG. Changes in intracardiac blood flow velocities and right and left ventricular stroke volumes with gestational age in the normal human fetus: a prospective Doppler echocardiographic study. Circulation. 1986 Dec;74(6):1208-16.
  • Cartier MS, Davidoff A, Warneke LA, Hirsh MP, Bannon S, Sutton MS, Doubilet PM. The normal diameter of the fetal aorta and pulmonary artery: echocardiographic evaluation in utero. AJR Am J Roentgenol. 1987 Nov;149(5):1003-7.
  • Achiron R, Golan-Porat N, Gabbay U, Rotstein Z, Heggesh J, Mashiach S, Lipitz S. In utero ultrasonographic measurements of fetal aortic and pulmonary artery diameters during the first half of gestation. Ultrasound Obstet Gynecol. 1998 Mar;11(3):180-4.
  • Zalel Y, Wiener Y, Gamzu R, Herman A, Schiff E, Achiron R. The three-vessel and tracheal view of the fetal heart: an in utero sonographic evaluation. Prenat Diagn. 2004;24:174-178.
  • Hautala J, Gissler M, Ritvanen A, Tekay A, Pitkänen-Argillander O, Stefanovic V, Sarkola T, Helle E, Pihkala J, Pätilä T, Mattila IP, Jokinen E, Räsänen J, Ojala T. The implementation of a nationwide anomaly screening programme improves prenatal detection of major cardiac defects: an 11-year national population-based cohort study. BJOG. 2019 Jun;126(7):864-873.
  • Itsukaichi M, Serikawa T, Yoshihara K, Suzuki H, Haino K, Yamaguchi M, Enomoto T; Niigata Fetal Cardiac Screening Study Group, Takakuwa K. Effectiveness of fetal cardiac screening for congenital heart disease using a combination of the four-chamber view and three-vessel view during the second trimester scan. J Obstet Gynaecol Res. 2018 Jan;44(1):49-53..
There are 17 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Article
Authors

Cihat Aksoy 0000-0001-8287-2547

Ayşe Şimşek 0000-0001-6387-4926

Özhan Özgür 0000-0001-9670-4720

Emel Durmaz 0000-0002-1125-9902

Ali Apaydın This is me 0000-0002-0205-311X

Timur Sindel 0000-0003-4537-0462

Project Number 2011.04.0103.030
Early Pub Date August 30, 2023
Publication Date September 1, 2023
Submission Date October 22, 2021
Published in Issue Year 2023 Volume: 9 Issue: 3

Cite

Vancouver Aksoy C, Şimşek A, Özgür Ö, Durmaz E, Apaydın A, Sindel T. The reference diameters of the three great vessels in the fetuses between 20-24 weeks by sonography. Akd Med J. 2023;9(3):241-6.