Beşikten Mezara Yaşam Boyu Devam Eden Mikrobiyota

Year 2023, Volume: 32 Issue: 1, 10 - 15, 31.03.2023

Yusuf Döğüş , Amin Deami , Sertap Döğüş , Zafer Yönden

https://doi.org/10.17827/aktd.1257562

Cited By: 1

Abstract

Vücudun bazı bölgesindeki mikrobiyal bileşim, insan kronolojik yaşını nispeten doğru bir şekilde tahmin edebilir. Belirli mikroorganizmaların belirli yaşlarda neden daha bol olduğu büyük ölçüde bilinmemekle birlikte, insan mikrobiyota araştırmaları, doğum ve ölüm arasında meydana gelen bir dizi mikrobiyal topluluk dönüşümünü aydınlatmıştır. Bireyin mikrobiyotanın aktivitesi ve bileşimi, konağın genetik geçmişi, yaşı, diyeti ve sağlık durumundan etkilendiği bilinmektedir. Formülle beslenen bebeklere kıyasla anne sütü ile beslenen bebekler, gençlere kıyasla yaşlılar ve asırlık insanlar, zayıf bireylere kıyasla obezler, sağlıklı veya inflamatuar barsak hastalıklarından (IBH) muzdarip insanlar arasındaki mikrobiyota bileşimi ve aktivitesindeki farklılıklar gösterilmiştir. Bu derlemede, doğumdaki birincil ardışıklıktan, hastalık veya antibiyotik kullanımına bağlı kesintilere ve ölümde mikrobiyal genişlemeye kadar olan aşamaları göstermektedir. Bu çalışmayla, insan bağırsak mikrobiyotasının işlevselliğine ilişkin mevcut anlayışımızı beşikten mezara kadar incelemekteyiz.

Keywords

Bağırsak Mikrobiyotası, Beslenme, Yaşam Evreleri

Supporting Institution

yok

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