Covid-19 Pandemic and Neurological Manifestations

Year 2020, Issue: Special Issue on COVID 19, 246 - 251, 20.03.2020

Ruken Şimşekoğlu , Temel Tombul

https://doi.org/10.21673/anadoluklin.738020

Cited By: 1

Abstract

A new corona virus outbreak (Corona virus disease, 2019, Covid-19), which started in December in Wuhan province of China, has been confirmed, and the virus spread to the whole world, creating a strong and serious pandemic.
Symptoms such as fever, cough, respiratory distress, diarrhea, and fatigue associated with Covid-19 are typical clinical findings. Some COVID‐19 patients also expressed neurologic findings like headache, dizziness, impaired consciousness, encephalitis, encephalopathy, cerebrovascular diseases, and peripheral nervous system damage. In some of these patients, the SARS-CoV-2 virus was isolated in the cerebrospinal fluid, in some cases, virus was detected in autopsy materials. In this review, the neurological signs and symptoms seen in Covid-19 infected patients and the mechanisms of the virus causing neuronal damage will be discussed.

Keywords

Covid-19, SARS-CoV-2, neurological signs

Covid-19 Pandemisi ve Nörolojik Tutulumlar

Abstract

Çin’in Wuhan eyaletinde Aralık ayında başlayan yeni bir korona virüs salgını (Corona virüs hastalığı-2019, Covid-19) doğrulandı ve virüs tüm Dünya’ya yayılarak güçlü ve ciddi bir pandemi oluşturdu. Covid-19’a bağlı görülen ateş, öksürük, solunum sıkıntısı, ishal, yorgunluk gibi semptomlar tipik klinik bulguları oluşturmaktadır. Bazı hastalarda ise baş ağrısı, dizziness, bilinç bozukluğu, ensefalit, ensefalopati, serebrovasküler hastalıklar, periferik sinir sistemi hasarları gibi nörolojik bulguların saptandığı bilinmektedir. Bu hastaların bir kısmında beyin omurilik sıvısında SARS-CoV-2 virüsü izole edilmiştir, bazı vakalarda ise otopsi materyallerinde virüs saptanmıştır. Bu derlemede Covid-19 ile enfekte hastalarda görülebilecek nörolojik belirti ve bulgular ve virüsün nöronal hasar yapabilme mekanizmaları tartışılacaktır.

Keywords

Covid-19, SARS-CoV-2, nörolojik belirtiler

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