Acil Serviste Akut Miyokard Enfarktüsü Tanısı Alıp Perkütan Koroner Girişim Uygulanan ve Kontrast Nefropati Gelişen Hastaların Analizi

Year 2021, Volume: 4 Issue: 2, 39 - 42, 29.06.2021

Yeliz Simsek , Selen Surer Salim Satar , Yahya Kemal İçen

Abstract

Amaç: Çalışmamızda, acil serviste akut miyokardiyal enfarktüs (AMI) tanısı alan ve perkutan koroner anjiyografi (PKA) uygulanan hastalarda, kontrast kaynaklı akut böbrek hasarının (CI-AKI) insidansını ve klinik prediktörlerini belirlemek amaçlandı.

Gereç ve Yöntemler: Çalışmamıza 422 hasta dâhil edildi. Hastaların, kan troponin, alanin aminotransferaz (ALT), aspartat aminotransferaz (AST) düzeyleri, başvuru sırasındaki ve PKA’dan üç gün sonraki serum kreatinin (Cr) düzeyleri, N-terminal pro-beyin natriüretik peptid (NT-proBNP) seviyeleri, elektrokardiyogram (EKG) bulguları, sol ventriküler ejeksiyon fraksiyonu (LVEF) ve anjiyografi sonuçlarını kaydettik. İncelenen parametreler ile CI-AKI oluşumları arasındaki ilişkiyi analiz ettik.

Bulgular: CI-AKI hastaların% 9.7'sinde görüldü. CI-AKI ile yaş, cinsiyet, AST, ALT, başvuru anındaki kreatinin düzeyleri, kardiyak disfonksiyon varlığı arasında istatistiksel olarak anlamlı bir ilişki vardı (P <0.001, P <0.01, P <0.01, P <0.05, P <0.001, P < 0.05).

Sonuç: Çalışmamıza göre; Yaş> 70, anormal pre-PCA kreatinin, kadın cinsiyet, yüksek bazal AST-ALT seviyeleri, kardiyak disfonksiyon, AMI tedavisi için PKA uygulanan hastalarda CI-AKI gelişimini öngörebilir.

Keywords

Acil, kontrast nefropati, perkutan koroner anjiyografi

Supporting Institution

YOK

Thanks

YOK

Analysis of Contrast-Induced Nephropathy in Patient with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention in the Emergency Department

Abstract

Aim: The purpose of this study was to determine the incidence and predictors of Contrast-induced acute kidney injury (CI-AKI) in emergency patients undergoing primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI).

Material and Methods: We enrolled electrocardiogram (ECG) findings, serum creatinine (Cr), troponin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) levels at pre-PCI and Cr levels post-PCI following three days. Patients’ N-terminal pro-brain natriuretic peptide (NT-proBNP) levels, left ventricular ejection fraction (LVEF) and results of angiography was recorded in 422 patients. We analyzed the relationship between examined parameters and the occurrences of CI-AKI.

Results: CI-AKI occurred in 9.7% of patients. There was a statistically significant relationship between occurrences CI-AKI and age, gender, AST, ALT, creatinine levels at admission, cardiac dysfunction (P<0.001, P<0.01, P<0.01, P<0.05, P<0.001, P<0.05).

Conclusion: According to our study; age>70 years, abnormal pre-PCI creatinine, female gender, high basal AST-ALT levels, cardiac dysfunction may predict CI-AKI development in patients who undergoing PCI for treatment of AMI.

Keywords

Emergency, contrast nephropathy, percutaneous coronary intervention

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