Radyoterapi Uygulanan Serviks Kanserli Hastalarda Tedavi Sonuçlarının Değerlendirilmesi ve Prognostik Faktörlerin İncelenmesi

Year 2019, Volume: 2 Issue: 2, 9 - 22, 30.05.2019

Cenk Ahmet Şen , Melek Gamze Aksu Aylin Fidan Korcum

Abstract

Amaç: Radyoterapi (RT) serviks kanserinde kullanılan etkili bir tedavi yöntemidir. Bu çalışmanın amacı RT uygulanmış serviks kanserli hastaların tedavi sonuçları ve prognostik faktörler açısından değerlendirilmesidir.

Gereç ve yöntem: Kliniğimizde adjuvan ve definitif RT uygulanmış evre IB-IVA serviks karsinomlu toplam 142 hasta retrospektif olarak incelendi. Ortalama izlem süresi 30 ay olup, tedaviye bağlı yan etkiler, sağkalım oranları ve prognostik faktörler değerlendirildi.

Bulgular: Bu çalışmada, RT alan tüm hastalarda evre, tedavi öncesi hemoglobin değeri, toplam RT süresi, eş zamanlı kemoterapi (KT) uygulanması, lenfovasküler invazyon durumu, tümör çapı ve RT sonrası rezidü tümör varlığı sağkalımda etkili prognostik faktörler olarak saptandı. Adjuvan ve definitif RT uygulanan hastalar arasında RT yan etkileri açısından anlamlı fark görülmedi.

Sonuç: RT serviks kanseri tedavisinde kabul edilebilir komplikasyon oranları ile tolere edilebilir ve etkili bir tedavi yöntemidir. Yan etkilerin değerlendirilmesinde geniş hasta sayılarını içeren prospektif çalışmalara gereksinim vardır.

Keywords

Serviks kanseri, Radyoterapi, Prognostik faktörler

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