Congenital toxoplasmosis

Year 2015, Volume: 4 Issue: 1, 62 - 69, 25.06.2016

Çağlar Yıldız , Özlem Bozoklu Akkar , Savaş Karakuş Ali Cetin

Abstract

Abstract

Congenital toxoplasmosis is a disease that can be seen worldwide. Fetus, newborn and infants with congenital Toxoplasma infection are at risk in terms of infection-related complications. As the gestational age increases, infection development risk of the fetus increases but the severity of the disease decreases. Most of the fetuses that are infected at the early stages of pregnancy and can’t be treated are lost in utero or in the neonatal period or severe neurologic and ophthalmologic sequel develops. Diagnosis must be made to differentiate the toxoplasmosis from the other intrauterine infections that present similar findings in the newborns and other causes of the retinal lesions. It is suggested to initiate the treatment in newborns diagnosed prenatally with congenital toxoplasmosis regardless of whether the mothers received treatment during pregnancy and to apply antiparasitic treatment in patients with confirmed diagnosis and strongly suspicious diagnosis.

Keywords: Congenital toxoplasmosis, diagnosis.

Özet

Konjenital toxoplazmosiz yagın görülebilen bir hastalıktır. Konjenital toxoplasma enfeksiyonuna maruz kalmış fetus, yenidoğan ve infantlar, komplikasyonlar yönünden risk altındadırlar. Gebelik haftası arttıkca, hastalığın şiddeti azalmasına ragmen, fetusda enfeksiyon gelişme riski artar. Erken gebelik haftalında enfekte olmuş fetusların çoğunda,  tedavi edilemeyenlerde, inutero veya yenidoğan döneminde tedavide geç kalındığı durumlara beyinde ve gözlerde sekeller gelişir. Toxoplazmosiz diğer intrauterine enfeksiyonlaradan ayırdedilmelidir. Yenidoğanda tedaviye başlamak için, gebeliği sırasında, süpheli ve kesin tanıyla tedavi alıp almamasına bakılmaksızın, konjenital topzoplazmosisin prenatal tanısının konması önerilmektedir.

Anahtar sözcükler: Konjenital toksoplazmozis,tanı

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