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Passiflora genus, importance of pharmacy and investigation of the samples which is sold by Passiflora (çarkıfelek) name in Turkey’s market

Year 2021, Volume: 14 Issue: 1, 138 - 145, 15.04.2021
https://doi.org/10.46309/biodicon.2021.814383

Abstract

Recent studies on the conventional use, chemical composition and biological effects of Passiflora incarnata, P. alata, P. edulis and P. caerulea species which have entered the our country’s market with fruits in recent years, which are grown as a climbing plant at the edges of parks and gardens and have medical value, which belong to Passifloraceae family and have economic value have been carried out in our study. It has been carried out for the diagnosis of drugs known as 'Passiflora' or 'Çarkıfelek' which are not naturally grown in our country but consumed especially for calming purposes and offered to the public for this purpose. Three samples called ‘passiflora’ or ‘çarkıfelek’ were purchased from different location in Ankara and As a result performed study out, it was found that two out of the three samples belonged to the fruits of Paliurus spina-christi Mill (Rhamnaceae). It was detected that sample called root of ‘passiflora’ or ‘çarkıfelek’ is fruit of Caiophora lateritia Klotzsch (Loasaceae) which is in the Central And region natural plant however, doesn’t grow in our country.

References

  • ARS, National. (2014). Germplasm Resources Information Network - (GRIN) [On Line Data Base].
  • Milliken, W., Klitgård, B. & Baracat, A. eds (2009 onwards). Neotropikey - Interactive key and information resources for flowering plants of the Neotropics.
  • Gupta, R. K., Kumar, D., Chaudhary, A. K., Maithani, M., Singh, R. (2012). Antidiabetic activity of Passiflora incarnata Linn. in streptozotocin-induced diabetes in mice. Journal of Ethnopharmacology, 139, 801-806.
  • Miroddi, M., Kalapai, G., Navarra, M., Minciullo, P. L., Gangemi, S. (2013). Passiflora incarnata L.: Ethnopharmacology, clinical application, safety and evaluation of clinical trials. Journal of Ethnopharmacology, 150, 791-804.
  • TF. (2017). Türk Farmakopesi 2017. Ankara: Artı 6 Reklam Matbaa Ltd. Şti., T.C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu 2017.
  • Braga, A., Stein, A. C., Stolz, A. D., Dallegrave, E., Buffon, A., Rego, J., Gosmann, G., Viana, A.F., Rates, S. M. K. (2013). Repeated administration of an aqueous spray-dried extract of the leaves of Passiflora alata Curtis (Passifloraceae) inhibits body weight gain without altering mice behavior. Journal of Ethnopharmacology, 145, 59-66.
  • Ulubelen, A., Oksuz S., Mabry T. J., Dellamonica G., Chopin J. (1982). C-Glycosylflavonoids from Passiflora pittieri, P. alata, P. ambigua and Adenia mannii. Journal of Natural Products, 45: 783-783.
  • Doyama, J.T., Rodriguesa, H.G., Novellia, E.L.B., Ceredab E., Vilegas W. (2005). Chemical investigation and effects of the tea of Passiflora alata on biochemical parameters in rats. Journal of Ethnopharmacology, 96, 371-374.
  • Wang, C., Xu, F. Q., Shang, J. H., Xiao, H., Fan, W. W., Dong, F. W., Hu, J.M., Zhou, J. (2013). Cycloartane triterpenoid saponins from water soluble of Passiflora edulis Sims and their antidepressant-like effects. Journal of Ethnopharmacology, 148, 812-817.
  • Li, H., Zhou, P., Yang, Q., Shen, Y., Deng, J., Li, L., Zhao, D. (2011). Comparative studies on anxiolytic activities and flavonoid compositions of Passiflora edulis ‘edulis’ and Passiflora edulis ‘flavicarpa’. Journal of Ethnopharmacology, 133, 1085-1090.
  • EP. (2013). European Pharmacopoeia, Council of Europe (2013). 10th ed., Strasbourg: European Directorate for the Quality of Medicines & HealthCare.
  • EMA. (2013). European Medicines Agency, EMA/ HMPC/ 669738/ 2013, Assesment report on Passiflora incarnata L., herba. http://ema.europa.eu
  • ESCOP. (2003). ESCOP Monographs. The scientific Foundation for Herbal Medicinal Prducts. Second Ed. Cmpletely revised and expanded. Thieme.
  • Koca Çalışkan, U. (2017). FFD Monografları, Bitkiler ve Etkileri. Eds. Demirezer, Ö., Ersöz, T., Saraçoğlu, İ., Şener, B., Köroğlu, A., Yalçın, F. N., Akademisyen Kitabevi, Ankara
  • Wasicky A., Hernandes L. S., Neto A. V., Moreno P. R. H., Bacchi E.F., Kato E. T. M., Yoshida M. (2015). Evaluation of gastroprotective activity of Passiflora alata. Revista Brasileira de Farmacognozia, 25, 407-412.
  • Montanher, A.B., Zucolotto, S.M., Schenkel, E.P., Fröde, T.S. (2007). Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model. Journal of Ethnopharmacology, 100, 281-288.
  • Singh, B., Singh, D., Goel, D. K. (2012). Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression. Journal of Ethnopharmacology, 139, 273-279.
  • Davis, P.H. (1967). ‘Paliurus’ In Flora of Turkey and The Aegean Islands. Vol, 2 eds. Davis, P. H., Cullen, J., Coode, M. J. E. Edinburgh University Press. Edinburgh.
  • PlantNet. (2020). Pl@ntNet app. http://plantnet.org
  • Slanis, A., Perea, M.C., Grau, A. (2016). Taxonomic revision of the genus Caiophora (Loasaceae) from Argentina: A new species C. sleumerii. Darwiniana, nueva serie, 4(2). 138-191.

Passiflora cinsi, eczacılıktaki önemi ve Türkiye piyasasında Passiflora (çarkıfelek) adı ile satılan örneklerin incelenmesi

Year 2021, Volume: 14 Issue: 1, 138 - 145, 15.04.2021
https://doi.org/10.46309/biodicon.2021.814383

Abstract

Çalışmada, ülkemiz piyasasına son yıllarda meyveleriyle de giren, park ve bahçe kenarlarında sarılıcı tırmanıcı bitki olarak yetiştirilen ve tıbbi değeri olan, Passifloraceae familyasında yer alan, ekonomik değere sahip Passiflora incarnata, P. alata, P. edulis ve P. cearulea türlerinin geleneksel kullanılışı, kimyasal bileşimi ve biyolojik etkilerinin son yıllarda yapılan çalışmaları derlenmiştir. Çalışmanın deneysel kısmı, ülkemizde doğal olarak yetişmeyen ancak özellikle sakinleştirici amaçla tüketilen ve bu amaçla halka sunulan ‘çarkıfelek’ ya da ‘passiflora’ adıyla bilinen drogların teşhisine yönelik olarak yürütülmüştür. Ankara’da 7 farklı yerden ‘passiflora’ veya ‘çarkıfelek’ adı ile satılan 3 örnek satın alınmıştır. Yapılan çalışmalar sonucunda ikisinin Paliurus spina-christi Mill. (karaçalı; Rhamnaceae). bitkisine ait meyveler olduğu saptanmıştır. Passiflora ya da çarkıfelek kökü adıyla satılan örneğin ise ülkemizde yetişmeyen, Orta And bölgesine ait bir bitki olan Caiophora lateritia Klotzsch (Loasaceae) meyveleri olduğu tespit edilmiştir. Elde ettiğimiz bu bulgular, Ankara piyasasında satılan passiflora, çarkıfelek örneklerinin doğru bitkiden elde edilmediğini ve drog olarak satılan bitki kısımlarının doğru olmadığını göstermiştir. Piyasada satışa sunulan örneklerin tedavi amacıyla kullanılması, doğru bitki ve doğru drog olmadığı için sakıncalıdır.

References

  • ARS, National. (2014). Germplasm Resources Information Network - (GRIN) [On Line Data Base].
  • Milliken, W., Klitgård, B. & Baracat, A. eds (2009 onwards). Neotropikey - Interactive key and information resources for flowering plants of the Neotropics.
  • Gupta, R. K., Kumar, D., Chaudhary, A. K., Maithani, M., Singh, R. (2012). Antidiabetic activity of Passiflora incarnata Linn. in streptozotocin-induced diabetes in mice. Journal of Ethnopharmacology, 139, 801-806.
  • Miroddi, M., Kalapai, G., Navarra, M., Minciullo, P. L., Gangemi, S. (2013). Passiflora incarnata L.: Ethnopharmacology, clinical application, safety and evaluation of clinical trials. Journal of Ethnopharmacology, 150, 791-804.
  • TF. (2017). Türk Farmakopesi 2017. Ankara: Artı 6 Reklam Matbaa Ltd. Şti., T.C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu 2017.
  • Braga, A., Stein, A. C., Stolz, A. D., Dallegrave, E., Buffon, A., Rego, J., Gosmann, G., Viana, A.F., Rates, S. M. K. (2013). Repeated administration of an aqueous spray-dried extract of the leaves of Passiflora alata Curtis (Passifloraceae) inhibits body weight gain without altering mice behavior. Journal of Ethnopharmacology, 145, 59-66.
  • Ulubelen, A., Oksuz S., Mabry T. J., Dellamonica G., Chopin J. (1982). C-Glycosylflavonoids from Passiflora pittieri, P. alata, P. ambigua and Adenia mannii. Journal of Natural Products, 45: 783-783.
  • Doyama, J.T., Rodriguesa, H.G., Novellia, E.L.B., Ceredab E., Vilegas W. (2005). Chemical investigation and effects of the tea of Passiflora alata on biochemical parameters in rats. Journal of Ethnopharmacology, 96, 371-374.
  • Wang, C., Xu, F. Q., Shang, J. H., Xiao, H., Fan, W. W., Dong, F. W., Hu, J.M., Zhou, J. (2013). Cycloartane triterpenoid saponins from water soluble of Passiflora edulis Sims and their antidepressant-like effects. Journal of Ethnopharmacology, 148, 812-817.
  • Li, H., Zhou, P., Yang, Q., Shen, Y., Deng, J., Li, L., Zhao, D. (2011). Comparative studies on anxiolytic activities and flavonoid compositions of Passiflora edulis ‘edulis’ and Passiflora edulis ‘flavicarpa’. Journal of Ethnopharmacology, 133, 1085-1090.
  • EP. (2013). European Pharmacopoeia, Council of Europe (2013). 10th ed., Strasbourg: European Directorate for the Quality of Medicines & HealthCare.
  • EMA. (2013). European Medicines Agency, EMA/ HMPC/ 669738/ 2013, Assesment report on Passiflora incarnata L., herba. http://ema.europa.eu
  • ESCOP. (2003). ESCOP Monographs. The scientific Foundation for Herbal Medicinal Prducts. Second Ed. Cmpletely revised and expanded. Thieme.
  • Koca Çalışkan, U. (2017). FFD Monografları, Bitkiler ve Etkileri. Eds. Demirezer, Ö., Ersöz, T., Saraçoğlu, İ., Şener, B., Köroğlu, A., Yalçın, F. N., Akademisyen Kitabevi, Ankara
  • Wasicky A., Hernandes L. S., Neto A. V., Moreno P. R. H., Bacchi E.F., Kato E. T. M., Yoshida M. (2015). Evaluation of gastroprotective activity of Passiflora alata. Revista Brasileira de Farmacognozia, 25, 407-412.
  • Montanher, A.B., Zucolotto, S.M., Schenkel, E.P., Fröde, T.S. (2007). Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model. Journal of Ethnopharmacology, 100, 281-288.
  • Singh, B., Singh, D., Goel, D. K. (2012). Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression. Journal of Ethnopharmacology, 139, 273-279.
  • Davis, P.H. (1967). ‘Paliurus’ In Flora of Turkey and The Aegean Islands. Vol, 2 eds. Davis, P. H., Cullen, J., Coode, M. J. E. Edinburgh University Press. Edinburgh.
  • PlantNet. (2020). Pl@ntNet app. http://plantnet.org
  • Slanis, A., Perea, M.C., Grau, A. (2016). Taxonomic revision of the genus Caiophora (Loasaceae) from Argentina: A new species C. sleumerii. Darwiniana, nueva serie, 4(2). 138-191.
There are 20 citations in total.

Details

Primary Language Turkish
Subjects Biochemistry and Cell Biology (Other)
Journal Section Research Article
Authors

Erkan Can Köse This is me 0000-0003-3491-6079

Ayşegül Köroğlu 0000-0002-8450-1376

Publication Date April 15, 2021
Submission Date October 23, 2020
Acceptance Date March 29, 2021
Published in Issue Year 2021 Volume: 14 Issue: 1

Cite

APA Köse, E. C., & Köroğlu, A. (2021). Passiflora cinsi, eczacılıktaki önemi ve Türkiye piyasasında Passiflora (çarkıfelek) adı ile satılan örneklerin incelenmesi. Biological Diversity and Conservation, 14(1), 138-145. https://doi.org/10.46309/biodicon.2021.814383

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