Year 2022,
Volume: 11 Issue: 4, 1102 - 1111, 31.12.2022
Hatice Mutlu Eyison
,
Seda Kıralp
,
Nesrin Özsoy Erdaş
,
Suna Cebesoy
References
- [1] The IUCN Red List Threatened Species, (September 2022 online: https://www.iucnredlist.org/search?query=acomys&searchType=species)
- [2] P.-O, Barome, et al. "Phylogeny of Acomys spinosissimus (Rodentia, Muridae) from north Malawi and Tanzania: evidence from morphological and molecular analysis." Biological Journal of the Linnean Society vol. 73 (3), 2001, pp. 321-340.
- [3] S. J., Steppan, et al. "Multigene phylogeny of the Old World mice, Murinae, reveals distinct geographic lineages and the declining utility of mitochondrial genes compared to nuclear genes." Molecular phylogenetics and evolution vol. 37(2), 2005, pp. 370-388.
- [4] D, Frynta, et al. "Phylogenetic relationships within the cahirinus-dimidiatus group of the genus Acomys (Rodentia: Muridae): new mitochondrial lineages from Sahara, Iran and the Arabian Peninsula." Zootaxa vol. 2660 (1), 2010, pp. 46-56.
- [5] P.-H., Fabre, et al. "A glimpse on the pattern of rodent diversification: a phylogenetic approach." BMC evolutionary biology vol.12 (1), 2012, pp. 1-19.
- [6] S., Renaud, et al. "Morphometrics and genetics highlight the complex history of Eastern Mediterranean spiny mice." Biological Journal of the Linnean Society vol.130 (3), 2020, pp. 599-614.
- [7] G., Pinheiro, et al. "The African spiny mouse (Acomys spp.) as an emerging model for development and regeneration." Laboratory animals vol. 52(6), 2018, pp. 565-576.
- [8] A.-E., Gonet, et al. "Obesity and diabetes mellitus with striking congenital hyperplasia of the islets of Langerhans in spiny mice (Acomys cahirinus)." Diabetologia vol. 1(3), 1966, pp.162-171.
- [9] E., Shafrir, Z., Ehud and K. Rony "Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil)." ILAR journal vol. 47(3), 2006, pp. 212-224.
- [10] B.-A., O'Connell, et al. "Sexually dimorphic placental development throughout gestation in the spiny mouse (Acomys cahirinus)." Placenta vol. 34(2), 2013, pp. 119-126.
- [11] N., Bellofiore, et al. "First evidence of a menstruating rodent: the spiny mouse (Acomys cahirinus)." American journal of obstetrics and gynecology vol. 216(1), 2017, pp. 40-51.
- [12] M., Maden, and J. A. Varholick. "Model systems for regeneration: the spiny mouse, Acomys cahirinus." Development vol. 147(4), 2020, dev167718
[13] H.-Ü., Lüleyap. Moleküler genetiğin esasları. Nobel Kitabevi, 2008.
- [14] C.-D., Dijkstra, and T., Sminia. "Normal anatomy, histology, immunohistology, ultrastructure, rat." Hemopoietic System. Springer, Berlin, Heidelberg, 1990, pp.249-256.
- [15] G., Pearse. "Normal structure, function and histology of the thymus." Toxicologic pathology vol. 34(5), 2006, pp. 504-514.
- [16] P., Thapa, and D. L., Farber. "The role of the thymus in the immune response." Thoracic surgery clinics vol. 29(2), 2019, pp. 123-131.
- [17] J.-F., Miller. "The function of the thymus and its impact on modern medicine." Science vol. 369 (6503), 2020, eaba2429.
- [18] P., Losco. "Normal development, growth and aging of the spleen." Pathobiology of the aging rat. 1992, pp. 75-93.
- [19] C.-F., Kuper, et al. "Immune system." Haschek and Rousseaux's handbook of toxicologic pathology. Academic Press, 2013, pp.1795-1862.
- [20] P., Balogh, G., Horváth, and A. K., Szakal. "Immunoarchitecture of distinct reticular fibroblastic domains in the white pulp of mouse spleen." Journal of histochemistry & cytochemistry vol. 52(10), 2004, pp. 1287-1298.
- [21] M.-A., Nolte, et al. "B cells are crucial for both development and maintenance of the splenic marginal zone." The Journal of Immunology vol.172(6), 2004, pp. 3620-3627.
- [22] M.-F., Cesta. "Normal structure, function, and histology of the spleen." Toxicologic pathology vol. 34(5), 2006, pp. 455-465.
- [23] A., Pennello et al. "Spiny mice (Acomys cahirinus) do not respond to thymus-independent type 2 antigens." Developmental & Comparative Immunology vol. 30(12), 2006, pp. 1181-1190.
- [24] J., Simkin et al. "Macrophages are necessary for epimorphic regeneration in African spiny mice." Elife vol. 6, 2017, e24623.
- [25] J.-O., Brant et al. "Cellular events during scar‐free skin regeneration in the spiny mouse, Acomys." Wound repair and regeneration 24.1 (2016): 75-88.
- [26] T.-R., Gawriluk et al. "Complex tissue regeneration in mammals is associated with reduced inflammatory cytokines and an influx of T cells." Frontiers in immunology vol.11, 2020, pp. 1695.
- [27] E., Kivanc, H. M., Eyison and S., Kiralp. "The distribution, habitat and conservation status of the Turkish spiny mouse, Acomys cilicicus Spitzenberger, 1978." 2017.
- [28] B.-K., Özdemirel et al. "Modelling Distribution of Asia Minor Spiny Mouse (Acomys Cilicicus) Using Maximum Entropy." International Journal of Environment and Geoinformatics vol.9(3), 2022, pp. 118-125.
Histological Evaluation of Spleen and Thymus of Acomys cilicicus
Year 2022,
Volume: 11 Issue: 4, 1102 - 1111, 31.12.2022
Hatice Mutlu Eyison
,
Seda Kıralp
,
Nesrin Özsoy Erdaş
,
Suna Cebesoy
Abstract
Acomys cilicicus, a species of the genus Acomys, which is the first mammal to have regeneration ability and attracts attention with its spiny-like structure, is an endemic species in Turkey. In recent years, species in the genus Acomys have been examined histologically due to their regeneration abilities. Although there are researches with regard to taxonomy of that species in the literature, there is not enough study on the subject of histology of its tissues. The aim of this study is to evaluate the available histomorphological data and documenting the normal microscobic features of the spleen and thymus tissues in A. cilicicus. In this study, 3 adult spiny mice (2 male and one female) were examined. All tissues obtained from those samples were fixed in 10% formalin and embedded in paraffin. Periodic Acid Schiff (PAS), Masson's trichrome, Gomori's silver soaking and Haematoxylin-Eosin were used for staining paraffin embedded sections. Histological analysis was carried out by using light microscopy. Histological data of the spleen and thymus tissues of A.cilicicus were reported in detailed.
Thanks
We thank Prof. Dr. Erkut Kıvanç for supplying the Acomys described in this report.
References
- [1] The IUCN Red List Threatened Species, (September 2022 online: https://www.iucnredlist.org/search?query=acomys&searchType=species)
- [2] P.-O, Barome, et al. "Phylogeny of Acomys spinosissimus (Rodentia, Muridae) from north Malawi and Tanzania: evidence from morphological and molecular analysis." Biological Journal of the Linnean Society vol. 73 (3), 2001, pp. 321-340.
- [3] S. J., Steppan, et al. "Multigene phylogeny of the Old World mice, Murinae, reveals distinct geographic lineages and the declining utility of mitochondrial genes compared to nuclear genes." Molecular phylogenetics and evolution vol. 37(2), 2005, pp. 370-388.
- [4] D, Frynta, et al. "Phylogenetic relationships within the cahirinus-dimidiatus group of the genus Acomys (Rodentia: Muridae): new mitochondrial lineages from Sahara, Iran and the Arabian Peninsula." Zootaxa vol. 2660 (1), 2010, pp. 46-56.
- [5] P.-H., Fabre, et al. "A glimpse on the pattern of rodent diversification: a phylogenetic approach." BMC evolutionary biology vol.12 (1), 2012, pp. 1-19.
- [6] S., Renaud, et al. "Morphometrics and genetics highlight the complex history of Eastern Mediterranean spiny mice." Biological Journal of the Linnean Society vol.130 (3), 2020, pp. 599-614.
- [7] G., Pinheiro, et al. "The African spiny mouse (Acomys spp.) as an emerging model for development and regeneration." Laboratory animals vol. 52(6), 2018, pp. 565-576.
- [8] A.-E., Gonet, et al. "Obesity and diabetes mellitus with striking congenital hyperplasia of the islets of Langerhans in spiny mice (Acomys cahirinus)." Diabetologia vol. 1(3), 1966, pp.162-171.
- [9] E., Shafrir, Z., Ehud and K. Rony "Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil)." ILAR journal vol. 47(3), 2006, pp. 212-224.
- [10] B.-A., O'Connell, et al. "Sexually dimorphic placental development throughout gestation in the spiny mouse (Acomys cahirinus)." Placenta vol. 34(2), 2013, pp. 119-126.
- [11] N., Bellofiore, et al. "First evidence of a menstruating rodent: the spiny mouse (Acomys cahirinus)." American journal of obstetrics and gynecology vol. 216(1), 2017, pp. 40-51.
- [12] M., Maden, and J. A. Varholick. "Model systems for regeneration: the spiny mouse, Acomys cahirinus." Development vol. 147(4), 2020, dev167718
[13] H.-Ü., Lüleyap. Moleküler genetiğin esasları. Nobel Kitabevi, 2008.
- [14] C.-D., Dijkstra, and T., Sminia. "Normal anatomy, histology, immunohistology, ultrastructure, rat." Hemopoietic System. Springer, Berlin, Heidelberg, 1990, pp.249-256.
- [15] G., Pearse. "Normal structure, function and histology of the thymus." Toxicologic pathology vol. 34(5), 2006, pp. 504-514.
- [16] P., Thapa, and D. L., Farber. "The role of the thymus in the immune response." Thoracic surgery clinics vol. 29(2), 2019, pp. 123-131.
- [17] J.-F., Miller. "The function of the thymus and its impact on modern medicine." Science vol. 369 (6503), 2020, eaba2429.
- [18] P., Losco. "Normal development, growth and aging of the spleen." Pathobiology of the aging rat. 1992, pp. 75-93.
- [19] C.-F., Kuper, et al. "Immune system." Haschek and Rousseaux's handbook of toxicologic pathology. Academic Press, 2013, pp.1795-1862.
- [20] P., Balogh, G., Horváth, and A. K., Szakal. "Immunoarchitecture of distinct reticular fibroblastic domains in the white pulp of mouse spleen." Journal of histochemistry & cytochemistry vol. 52(10), 2004, pp. 1287-1298.
- [21] M.-A., Nolte, et al. "B cells are crucial for both development and maintenance of the splenic marginal zone." The Journal of Immunology vol.172(6), 2004, pp. 3620-3627.
- [22] M.-F., Cesta. "Normal structure, function, and histology of the spleen." Toxicologic pathology vol. 34(5), 2006, pp. 455-465.
- [23] A., Pennello et al. "Spiny mice (Acomys cahirinus) do not respond to thymus-independent type 2 antigens." Developmental & Comparative Immunology vol. 30(12), 2006, pp. 1181-1190.
- [24] J., Simkin et al. "Macrophages are necessary for epimorphic regeneration in African spiny mice." Elife vol. 6, 2017, e24623.
- [25] J.-O., Brant et al. "Cellular events during scar‐free skin regeneration in the spiny mouse, Acomys." Wound repair and regeneration 24.1 (2016): 75-88.
- [26] T.-R., Gawriluk et al. "Complex tissue regeneration in mammals is associated with reduced inflammatory cytokines and an influx of T cells." Frontiers in immunology vol.11, 2020, pp. 1695.
- [27] E., Kivanc, H. M., Eyison and S., Kiralp. "The distribution, habitat and conservation status of the Turkish spiny mouse, Acomys cilicicus Spitzenberger, 1978." 2017.
- [28] B.-K., Özdemirel et al. "Modelling Distribution of Asia Minor Spiny Mouse (Acomys Cilicicus) Using Maximum Entropy." International Journal of Environment and Geoinformatics vol.9(3), 2022, pp. 118-125.