Buparvakuon

Year 2023, , 61 - 64, 29.12.2023

Muhittin Uslu , Rahmi Canbar

https://doi.org/10.58833/bozokvetsci.1358681

Abstract

Theileriosis tropikal ve subtropikal bölgelerde Theileria spp. türlerinin Ixodidae ailesi ait kenelerle nakledilmesi sonucu gelişen bir tür kan protozoonu enfeksiyonudur. Hastalık özellikle ruminantlarda yüksek mortalite ve morbitide ile seyretmektedir. Perakut vakalarda ilk birkaç gün içinde ölümler gözlenirken, akut vakalarda ilk haftalar içinde ölümler gözlendiği bildirilmektedir. Hastalarda ateş, lenfadenopati, solunum güçlüğü, kalp atım sayısında artış, süt veriminde azalma, canlı ağırlık kaybı, abort ve ölümler gözlenmektedir. Hidroksinaftokinon grubu antiprotozoal ilaç olan buparvakuon hastalığın tedavisinde kullanılan en etkili tek ilaçtır. Sığırlarda, theileriosis enfeksiyonuna karşı ilacın 2.5 mg/kg dozunda kas içi kullanımı önerilmekle birlikte hekim tarafından gerekli görüldüğü durumda ise 2-3 gün sonra aynı dozaj rejiminde kullanılabilir. İlacın kullanımı durumunda uygulandığı bölgede lokal reaksiyonlar gelişebildiği, ayrıca aşılarla birlikte ve gebe hayvanlarda kullanımı önerilmemektedir. İlaç genel anlamda güvenli kabul edilmektedir. Hastalığın kenelerle nakil edilmesi nedeni ile tedavi protokolüne bir ektoparaziter ajan eklenmesi tavsiye edilmektedir. Bu derlemede theileriosis tedavisinde buparvakuon kullanımı hakkında bilgiler verilmeye çalışılmıştır.

Keywords

Buparvakuon, Theileriosis, Hayvan, Türleri

Ethical Statement

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Supporting Institution

Yok

Project Number

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Thanks

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BUPARVAQUONE

Abstract

Theileriosis is a type of blood protozoan infection caused by the transmission of Theileria spp. species in tropical and subtropical regions by ticks belonging to the Ixodidae family. The disease progresses with high mortality and morbidity especially in ruminants. While deaths are observed in the first few days in peracute cases, it is reported that deaths are observed within the first weeks in acute cases. Fever, lymphadenopathy, respiratory distress, increase in heart rate, decrease in milk yield, weight loss, abortion and death are observed in patients. Buparvaquone, an antiprotozoal drug of the hydroxynaphthoquinone group, is the single most effective drug used in the treatment of the disease. Although it is recommended to use 2.5 mg/kg intramuscularly against theileriosis infection in cattle, it can be used in the same dosage regimen 2-3 days later if deemed necessary by the physician. In case of use of the drug, local reactions may develop in the area where it is applied, and it is not recommended to be used with vaccines and in pregnant animals. The drug is generally considered safe. Since the disease is transmitted by ticks, it is recommended to add an ectoparasitic agent to the treatment protocol. In this review, it has been tried to give information about the use of buparvaquone in the treatment of theileriosis.

Keywords

Buparvaquone, Theileriosis, Animal, Species

Project Number

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