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INVESTIGATION ON ANTIMICROBIAL EFFECTS OF SOME LICHEN SPECIES COLLECTED FROM KASTAMONU REGION

Year 2011, Volume: 23 Issue: 1, 21 - 31, 01.06.2011

Abstract

Lichens are symbiotic organisms of fungi and photobionts (algae or cyanobacteria). It has been known for many years that some secondary metabolites produced by lichens have antagonistic effects on different microorganisms, yeasts and algae. In this study, in vitro antimicrobial activity of Pseudevernia furfurace, Hypogymnia tubulosa, Evernia divaricata, Letharia vulpina samples collected from Kastamonu region were examined against Candida albicans ATCC 26555, Salmonella enterica Serotype Typhium SL 1344, Escherichia coli ETEC LM 63083, Shigella flexneri and Bacillus megaterium. The antimicrobial activity of samples was evaluated by disc diffusion method and the results were supported by MIC (minimum inhibitory concentration) and MBC/MFC (minimum bactericidal/fungicidal concentration) tests. According to the results, among the lichen samples, Letharia vulpina presented an antimicrobial activity against B. megaterium, where Pseudevernia furfurace had an antimicrobial activity against S. flexneri and B. megaterium, and Evernia divaricata against C. albicans, S. flexneri and B. megaterium. On the other hand, Hypogymnia tubulosa presented no antimicrobial activity

References

  • Altuner EM (2008). Bazı karayosunu türlerinin antimikrobiyal aktivitesinin belirlenmesi, Ph. D., Ankara Üniversitesi, Fen Bilimleri Enstitüsü, Ankara.
  • Altuner EM, Çetin B (2009). Antimicrobial activity of Thuidium delicatulum (Bryopsida) extracts. Kafkas Üniversitesi, Fen Bilimleri Enstitüsü Dergisi. 2: 85-92.
  • Andrews JM (2007). BSAC standardized disc susceptibility testing method (version 6). Journal of Antimicrobial Chemotherapy, 60:20-41.
  • Baron G (1999). Understanding Lichens. Richmond Publishing, Slough, England. Chapters 10, 11 and 12 of The Mycota, Vol IX, Fungal Associations, Springer, Berlin.
  • Basile A, Vuotto ML, Ielpo TL, Moscatiello V, Ricciardi L, Giordano S, Cobianchi RC (1998). Antibacterial activity in Rhynchostegium riparoides (Hedw.) Card. Extract (Bryophyta). Phytotherapy Research, 12: 146 - 148.
  • Burkholder PR, Ans AW, McVeigh I, Thornton HK (1994). Antibiotic Activity of Lichens, Botany, 30:250-255.
  • Brodo IM, Sharnoff SD (2001). Lichens of North America. New Haven, Connecticut: Yale University Press.
  • Cowan MM (1999). Plant products as antimicrobial agents. Clinical Microbiology Reviews, 564-582.
  • Geissman TA (1963). Flavonoid compounds, tannins, lignins and related compounds, p. 265. In M. Florkin and E. H. Stotz (ed.), Pyrrole pigments, isoprenoid compounds and phenolic plant constituents, vol. 9. Elsevier, New York.
  • Gucin F, Ozturk Ş, Dulger B, Guvenc Ş (1997). Umbilicaria crustulosa (Ach.) Frey’nin antimikrobiyal aktivitesi uzerine bir araştırma, Ekoloji ve Çevre Dergisi. 24: 21 -24.
  • Hammer KA, Carson CF, Riley TV (1999). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86: 985-990.
  • Harmala P, Hiltunen R, Oksman C (1992). Isolation and in vitro cultuvation of lichen algae and their antimicrobial properties. Fitoterapia, 3:217- 225.
  • Huneck S, Yoshimura I (1996). Identification of Lichen Substances. Springer, Berlin
  • Kotan E, Alpsoy L, Anar M, Aslan A, Agar G (2011). Protective role of methanol extract of Cetraria islandica (L.) against oxidative stress and genotoxic effects of AFB1 in human lymphocytes in vitro. Toxicology and Indsutrial Health, doi: 10.1177/0748233710394234
  • Lawrey JD (1984). Biology of Lichenized Fungi, New York.
  • Lawrey JD (1986). Biological Role of Lichen Substances, The Bryologist, 89:111-122.
  • Mahasneh AM, El-Oqlah AA (1999). Antimicrobial activity of extracts of herbal plants used in the traditional medicine of Jordan. J Ethnopharmacol, 64: 271-276.
  • Molnár K, Farkas E (2010). Current results on biological activities of lichen secondary metabolites: a review. Z Naturforsch C, 65:157-173.
  • Müller K (2001). Pharmaceutically relevant metabolites from lichens. Applied Microbiology and Biotechnology, 56:9-16.
  • Osmanağaoğlu O, Yıldız A, Sacılık SC (2000). Türkiye’deki Farklı Bolgelerden İzole Edilen Likenlerin Antimikrobiyal Aktiviteleri, Türk Mikrobiyol Cem Derg. 30: 17-19.
  • Samidurai K, Saravanakumar A (2009). Antibacterial Activity of Pemphis Acidula Forst. Global Journal of Pharmacology, 3(2):113-115.
  • Silici S, Koc AN (2006). Comparative study of in vitro methods to analyse the antifungal activity of propolis against yeasts isolated from patients with superficial mycoses. Letters in Applied Microbiology, 43:318-324.
  • Takai M, Ueraha Y, Beisler JA (1979). Usnic acid derivatives as potential antineoplastic agents, J Med Chem. 22: 1380.
  • Vartia KO (1973). Antibiotics in lichens. In: The Lichens (Ahmadjian V. and Hale M. E., eds.), Academic Press, New York, pp. 547-561.
Year 2011, Volume: 23 Issue: 1, 21 - 31, 01.06.2011

Abstract

References

  • Altuner EM (2008). Bazı karayosunu türlerinin antimikrobiyal aktivitesinin belirlenmesi, Ph. D., Ankara Üniversitesi, Fen Bilimleri Enstitüsü, Ankara.
  • Altuner EM, Çetin B (2009). Antimicrobial activity of Thuidium delicatulum (Bryopsida) extracts. Kafkas Üniversitesi, Fen Bilimleri Enstitüsü Dergisi. 2: 85-92.
  • Andrews JM (2007). BSAC standardized disc susceptibility testing method (version 6). Journal of Antimicrobial Chemotherapy, 60:20-41.
  • Baron G (1999). Understanding Lichens. Richmond Publishing, Slough, England. Chapters 10, 11 and 12 of The Mycota, Vol IX, Fungal Associations, Springer, Berlin.
  • Basile A, Vuotto ML, Ielpo TL, Moscatiello V, Ricciardi L, Giordano S, Cobianchi RC (1998). Antibacterial activity in Rhynchostegium riparoides (Hedw.) Card. Extract (Bryophyta). Phytotherapy Research, 12: 146 - 148.
  • Burkholder PR, Ans AW, McVeigh I, Thornton HK (1994). Antibiotic Activity of Lichens, Botany, 30:250-255.
  • Brodo IM, Sharnoff SD (2001). Lichens of North America. New Haven, Connecticut: Yale University Press.
  • Cowan MM (1999). Plant products as antimicrobial agents. Clinical Microbiology Reviews, 564-582.
  • Geissman TA (1963). Flavonoid compounds, tannins, lignins and related compounds, p. 265. In M. Florkin and E. H. Stotz (ed.), Pyrrole pigments, isoprenoid compounds and phenolic plant constituents, vol. 9. Elsevier, New York.
  • Gucin F, Ozturk Ş, Dulger B, Guvenc Ş (1997). Umbilicaria crustulosa (Ach.) Frey’nin antimikrobiyal aktivitesi uzerine bir araştırma, Ekoloji ve Çevre Dergisi. 24: 21 -24.
  • Hammer KA, Carson CF, Riley TV (1999). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86: 985-990.
  • Harmala P, Hiltunen R, Oksman C (1992). Isolation and in vitro cultuvation of lichen algae and their antimicrobial properties. Fitoterapia, 3:217- 225.
  • Huneck S, Yoshimura I (1996). Identification of Lichen Substances. Springer, Berlin
  • Kotan E, Alpsoy L, Anar M, Aslan A, Agar G (2011). Protective role of methanol extract of Cetraria islandica (L.) against oxidative stress and genotoxic effects of AFB1 in human lymphocytes in vitro. Toxicology and Indsutrial Health, doi: 10.1177/0748233710394234
  • Lawrey JD (1984). Biology of Lichenized Fungi, New York.
  • Lawrey JD (1986). Biological Role of Lichen Substances, The Bryologist, 89:111-122.
  • Mahasneh AM, El-Oqlah AA (1999). Antimicrobial activity of extracts of herbal plants used in the traditional medicine of Jordan. J Ethnopharmacol, 64: 271-276.
  • Molnár K, Farkas E (2010). Current results on biological activities of lichen secondary metabolites: a review. Z Naturforsch C, 65:157-173.
  • Müller K (2001). Pharmaceutically relevant metabolites from lichens. Applied Microbiology and Biotechnology, 56:9-16.
  • Osmanağaoğlu O, Yıldız A, Sacılık SC (2000). Türkiye’deki Farklı Bolgelerden İzole Edilen Likenlerin Antimikrobiyal Aktiviteleri, Türk Mikrobiyol Cem Derg. 30: 17-19.
  • Samidurai K, Saravanakumar A (2009). Antibacterial Activity of Pemphis Acidula Forst. Global Journal of Pharmacology, 3(2):113-115.
  • Silici S, Koc AN (2006). Comparative study of in vitro methods to analyse the antifungal activity of propolis against yeasts isolated from patients with superficial mycoses. Letters in Applied Microbiology, 43:318-324.
  • Takai M, Ueraha Y, Beisler JA (1979). Usnic acid derivatives as potential antineoplastic agents, J Med Chem. 22: 1380.
  • Vartia KO (1973). Antibiotics in lichens. In: The Lichens (Ahmadjian V. and Hale M. E., eds.), Academic Press, New York, pp. 547-561.
There are 24 citations in total.

Details

Primary Language English
Journal Section Research Articles
Authors

Ergin Murat Altuner

Talip Çeter This is me

Duygu Demirkapı This is me

Kerime Özkay This is me

Uğur Hayal This is me

Gamze Eser This is me

Publication Date June 1, 2011
Published in Issue Year 2011 Volume: 23 Issue: 1

Cite

Communications Faculty of Sciences University of Ankara Series C-Biology.

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