Akut anterior ST segment miyokard infarktüsü sonrası GRACE risk skorunun sol ventrikül ejeksiyon fraksiyonundaki prediktif değeri

Year 2019, Volume: 44 Issue: 3, 819 - 828, 30.09.2019

Veysel Tosun , Necmettin Korucuk Ali Yaşar Kılınç Ünal Güntekin

https://doi.org/10.17826/cumj.459500

Abstract

Amaç: Bu çalışmanın amacı, akut anteriyor segment miyokard infarktüsü (AMI) sonrası sol ventrikül ejeksiyon fraksiyonu (LVEF) için GRACE skorunun prediktif değerini araştırmaktır. Akut miyokard enfarktüsünde (AMI) hızlı ve tam reperfüzyona rağmen, sol ventrikül fonksiyonunun yetersiz düzelmesi LVEF'de azalmaya neden olabilir.

Yöntemler: AMİ ile başvuran 710 hasta retrospektif olarak incelendi ve 290 hasta çalışmaya alındı. Hastalar LVEF'ye göre iki gruba ayrıldı ve LVEF <%50 olanlar deprese EF grubu (grup 1) olarak tanımlandı, >% 50 olanlar ise korunmuş EF grubu (grup 2) olarak tanımlandı. Tüm hastaların GRACE risk skorları hesaplandı.

Bulgular: Grup 1'e 132 hasta dahil edildi, 158 hasta grup 2'ye dahil edildi. Hastane içi ölüm GRACE risk skoru ve hastane içi ölüm / MI GRACE risk skoru grup 1'de daha yüksek bulundu. Risk skorlaro ve LVEF arasında anlamlı negatif korelasyon bulundu. Çok değişkenli regresyon analizinde hastane içi ölüm risk skoru ve hastane içi ölüm / MI risk skorunun depresif LVEF'nin bağımsız olarak öngördürücüsü olduğu bulunmuştur.

Sonuçlar: GRACE risk skoru, primer PKG ile tedavi edilen akut ön segment AMI hastalarında depresif LVEF'yi öngörmede klinik olarak önemli bir role sahiptir.

Keywords

risk tabakalanması, sol ventrikül fonksiyonu, akut miyokard infarktüsü, kalp yetmezliği

The predictive value of GRACE risk score on the left ventricular ejection fraction after acute anterior ST-segment myocardial infarction

Abstract

Purpose: The aim of the study is to investigate the predictive value of GRACE score for left ventricular ejection fraction (LVEF) after acute anterior segment acute myocardial infarction (AMI). Despite rapid and complete reperfusion in AMI, inadequate recovery of left ventricular function may result in a decrease in LVEF.

Materials and Methods: We retrospectively analyzed 712 patients presented with AMI and 290 patients were included. Patients were divided into two groups according to LVEF and a value <50% was defined as depressed EF group (group 1), a value ≥50% was defined as preserved EF group (group 2). The GRACE risk scores of all patients were calculated.

Results: 132 patients were included in the group 1, 158 patients were included in the group 2. In-hospital death GRACE risk score and in-hospital death/MI GRACE risk score were higher in group 1. A significant negative correlation was found between risk scores and LVEF. In multivariate regression analysis, in-hospital death risk score, and in-hospital death/MI risk score were found to be independently predictors of depressed LVEF.

Conclusion: GRACE risk score has a clinically important role predicting depressed LVEF in acute anterior segment AMI patients treated with primary PCI. 

Keywords

risk stratification, left ventricular function, acute myocardial infarction, , heart failure

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