Effects of bedside adequacy assessment in thyroid cytology on cytological sufficiency and the final histopathological diagnosis

Year 2020, Volume: 45 Issue: 3, 1173 - 1181, 30.09.2020

Tuğba Toyran , Gülname Fındık Güvendi , Yasemen Adalı , Hüseyin Üstün

https://doi.org/10.17826/cumj.733150

Abstract

Purpose: The thyroid fine needle aspiration cytology (FNAC) is a fast, reliable, and economical method for the interpretation of thyroid nodules. This method contributes to the later management of patients and reduces unnecessary surgical interventions. This study aimed to demonstrate the contribution of bedside adequacy assessment during FNAC to the accuracy rates of cytological competence and final histological diagnosis.
Materials and Methods: The study included 443 patients who underwent FNAC in a university hospital between 2012 and 2015. Correlations between the histological diagnosis categories of patients who had and who did not have bedside adequacy assessment were compared per sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy.
Results: As a result of comparison of cytological and histopathological diagnoses, 30.7% sensitivity, ‎75% specificity, 50% positive predictive value, 57.1% negative predictive value and 55.1% diagnostic accuracy were found in the group with bedside adequacy assesment. Whereas in the group without bedside adequacy assessment, 50% sensitivity, 69.2% specificity, 42.8% positive predictive value, 75% negative predictive value, and 63.1% diagnostic accuracy were found
Conclusion: Bedside adequacy assessment increases the cytological adequacy proportion, but does not contribute to the diagnostic accuracy rate.

Keywords

Bedside Adequacy Assessment, Thyroid, Fine-Needle Aspiration Cytology

Tiroid sitolojisinde hasta başı yeterlilik çalışmasının sitolojik yeterlilik ve kalıcı histopatolojik tanıya etkisi

Abstract

Amaç: Tiroid ince iğne aspirasyon sitolojisi (İİAS), tiroid nodüllerinin değerlendirilmesi için; hızlı, güvenilir, ekonomik bir yöntemdir. Bu yöntem hastaların ileri dönemde yönetimine katkı sağlamakta ve gereksiz cerrahi uygulamaları azaltmaktadır. Bu çalışmada İİAS sırasında, hasta başında yeterlilik değerlendirilmesinin, sitolojik yeterlilik ve histolojik kesin tanıda doğruluk oranlarına ne kadar katkısı olduğunu göstermek amaçlandı.
Gereç ve Yöntem: Çalışmaya, 2012-2015 yılları arasında, bir üniversite hastanesinde İİAS uygulanmış 443 hasta dâhil edilmiştir. Hasta başında yeterlilik değerlendirilen ve değerlendirilmeyen olguların histolojik tanı kategorileriyle korelasyonu; duyarlılık, özgüllük, pozitif öngörü değeri, negatif öngörü değeri, tanısal doğruluk oranlarına göre karşılaştırılmıştır.
Bulgular: Sitolojik ve histopatolojik tanıların karşılaştırılması sonucunda, hasta başı yeterlilik değerlendirilen grupta, duyarlılık %30,7, özgüllük %75, pozitif öngörü değeri %50, negatif öngörü değeri %57,1, tanısal doğruluk %55,1 olarak bulunmuştur. Hasta başı yeterlilik değerlendirilmeyen grupta ise duyarlılık %50, özgüllük %69,2, pozitif öngörü değeri %42,8 negatif öngörü değeri %75, tanısal doğruluk %63,1 olarak bulunmuştur.
Sonuç: Hasta başı yeterlilik değerlendirilmesi, sitolojik yeterlilik oranını arttırır, ancak tanısal doğruluk oranına katkıda bulunmaz.

Keywords

Hasta başı yeterlilik değerlendirilmesi, Tiroid, İnce iğne aspirasyon sitolojisi

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