Orta serebral arter enfarktlarında nötrofil/lenfosit oranı ve ortalama trombosit hacminin kısa dönem prognoza etkisi

Year 2020, Volume: 45 Issue: 4, 1572 - 1579, 27.12.2020

Turgay Demir , Devrim Söğüt Mehmet Taylan Peköz , Şebnem Bıçakcı

Abstract

Amaç: Bu çalışmada akut iskemik inme tanısı alan ve orta serebral arter (OSA) enfarktı saptanan hastalarda nötrofil/lenfosit oranı (NLR) ve ortalama trombosit hacminin (MPV) kısa dönem prognoz üzerine etkisinin araştırılması amaçlanmıştır.
Gereç ve Yöntem: Bir üniversite hastanesi Nöroloji Yoğun Bakım ve İnme Ünitesine akut iskemik inme tanısıyla yatan ve OSA enfarktı saptanan hastalar alınmıştır. Kontrol grubu olarak Nöroloji polikliniğine başağrısı yakınmasıyla başvurmuş, inme öyküsü olmayan, bilinen sistemik hastalığı olmayan yaş ve cinsiyet dağılımı benzer hastalar bu çalışmaya alınmıştır. Hasta ve kontrol grubunun NLR ve MPV değerleri kaydedildi. Ayrıca hastaların yatış sırasında ve taburculuk sırasındaki NIHSS (National Institute of Health Stroke Scale) skoru, taburculuk sırasındaki modifiye Rankin skoru (mRS) kaydedildi.
Bulgular: Çalışmaya dahil edilen 72 hastanın % 58,3’ü (n=42) erkekti. Hasta ve kontrol grubu NLR ve MPV ortalamaları açısından karşılaştırılmış ve her iki parametre de hasta grubunda kontrol grubuna göre daha yüksek bulunmuştur. NLR kötü prognoz grubunda iyi prognoz grubuna göre ve mortalite grubunda sağ kalım grubuna göre daha yüksek saptanmıştır.
Sonuç: Klinisyenler OSA enfarktı olan hastalarda NLR ile kısa dönem prognoz tayininde kullanabilirler ve bu kolayca belirlenebilir ölçüm, objektif, basit ve kolay ulaşılabilirdir, aynı zamanda herhangi bir ek maliyete de yol açmaz.

Keywords

Akut iskemik inme, nötrofil/lenfosit oranı, orta serebral arter, ortalama trombosit hacmi, prognoz

Supporting Institution

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Thanks

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The effect of neutrophyl/lymphocyte ratio and mean platelet volume on short-term prognosis in middle cerebral artery infarctions

Abstract

Purpose: The aim of this study was to investigate the effect of neutrophil / lymphocyte ratio (NLR) and mean platelet volume (MPV) on short-term prognosis in patients with acute ischemic stroke who had middle cerebral artery (MCA) territory infarction.
Materials and Methods: The study included patients who were admitted to a University Hospital Neurology Intensive Care and Stroke Unit with the diagnosis of acute ischemic stroke and had MCA territory infarction. The control group consisted of patients with similar age and gender distribution applied to the Neurology outpatient clinic with the complaint of headache, without history of stroke or systemic disease. NLR and MPV values of groups were recorded. In addition, the patients' NIHSS (National Institute of Health Stroke Scale) score at hospitalization and at discharge and the modified Rankin score (mRS) at discharge were recorded.
Results: Of the 72 patients 58.3% (n = 42) included in the study were male. The patient and control groups were compared in terms of mean NLR and MPV values, and both parameters were higher in patient group than the control group. NLR was higher in poor prognosis group than the good prognosis group and in mortality group compared to the survival group.
Conclusion: Physicians can use NLR for short-term prognosis in patients with MCA infarction, and this easily identifiable measurement is objective, simple and easily accessible, and does not cause any additional costs.

Project Number

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