Impact of sexual and neurogenic lower urinary tract dysfunction on multiple sclerosis patients' quality of life and health perceptions

Year 2023, Volume: 48 Issue: 2, 448 - 456, 02.07.2023

Neslihan Eşkut , Aslı Köşkderelioğlu

https://doi.org/10.17826/cumj.1239533

Abstract

Purpose: To investigate the impact of neurogenic lower urinary tract dysfunction (NLUTD) and sexual dysfunction (SD) on multiple sclerosis (MS) patients' quality of life and health perceptions and evaluate the possible relationship with disease parameters.
Materials and Methods: A total of 192 patients with MS were included in the study. Along with the King's Health (KHQ) and COOP/WONCA questionnaires, Arizona Sexual Experience Scale (ASEX), Beck Depression Scale (BDI), Monitoring My Multiple Sclerosis Scale (MMMS) were used to evaluate the patients’ quality of life and self-perception of health.
Results: The median age of the patients was 39.5 years (18–66 years). In contrast, SD was present in 34.4%, 51.6% of the patients presented with NLUTD. Patients with NLUTD had significant differences in terms of age, education level, duration of disease, EDSS, BDI, ASEX, and MMMS scores. The majority of the study group had minor disability (82.8% had an EDSS score less than 3). Patients with SD showed higher disability, depression, and disrupted self-perception of their health status. In addition, quality of life measures correlated with the presence of NLUTD, SD and depression along with higher disability and altered self perception of their health status.
Conclusion: NLUTD and SD significantly effect quality of life and well being. Increasing awareness about the impact of NLUTD and SD symptoms in patients with MS will provide a comprehensive approach in clinical practice.

Keywords

Multiple sclerosis, Neurogenic lower urinary tract dysfunction, Sexual Dysfunction, Self Perceptions of Health, Quality of life

Cinsel ve nörojenik alt üriner sistem disfonksiyonunun multipl skleroz hastalarının yaşam kalitesi ve sağlık algıları üzerindeki etkisi

Abstract

Amaç: Nörojenik alt üriner sistem disfonksiyonu (NLUTD) ve cinsel disfonksiyonun (CD) multipl skleroz hastalarının yaşam kalitesi ve sağlık algıları üzerindeki etkisini araştırmak ve hastalık parametreleri ile olası ilişkisini değerlendirmek.
Gereç ve Yöntem: Çalışmaya toplam 192 MS hastası dahil edildi. Hastaların yaşam kalitelerini ve sağlık algılarını değerlendirmek için King’s Yaşam anketi (KHQ) ve COOP/WONCA anketleri yanı sıra Arizona cinsel deneyim ölçeği (ASEX), Beck depresyon ölçeği (BDÖ), Multipl skleroz izlem ölçeği (MMMS) kullanıldı.
Bulgular: Hastaların yaş ortancası 39,5 (18-66) idi. Hastaların % 34,4’ünde CD mevcutken, % 51,6’sında NLUTD mevcuttu. NLUTD olan hastaların yaş, eğitim düzeyi, hastalık süresi, EDSS, BDÖ, ASEX ve MMMS skorları açısından anlamlı fark vardı. Çalışma grubunun büyük çoğunluğunun hafif özürlüğü vardı (% 82,8’inin EDSS puanı üçten azdı). CD olan hastalarda daha fazla özürlülük, depresyon ve sağlık durumlarına ilişkin algılarında bozulma görüldü. Ek olarak, yaşam kalitesi ölçümleri, NLUTD, CD ve depresyon varlığıyle birlikte daha fazla özürlülük ve sağlık durumlarıyla ilişkili değişen algıları ile korele olarak bulundu.
Sonuç: NLUTD ve CD yaşam kalitesini ve iyilik halini önemli ölçüde etkiler. MS’li hastalarda NLUTD ve CD semptomlarının etkisi konusunda farkındalığın artması, klinik pratikte kapsamlı bir yaklaşım sağlayacaktır.

Keywords

Multiple sclerosis, Neurogenic lower urinary tract dysfunction, Sexual Dysfunction, Self Perceptions of Health, Quality of life

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