Anatomic analysis of etiology and incidence of melasma development in women

Year 2024, Volume: 49 Issue: 2, 343 - 352, 30.06.2024

Ayşe Gül Kabakcı , Çağlar Cengizler , Memduha Gülhal Bozkır

https://doi.org/10.17826/cumj.1424519

Abstract

Purpose: Melasma is a condition originating from facial hyperpigmentation, significantly affecting quality of life. While its etiology is multifactorial, lifestyle and external factors are crucial in its manifestation. The main objective of this study was to unveil the relationship between environmental factors and melasma incidence numerically. Also, optimizing the treatment strategies and aiding the development of computerized diagnostic tools were aimed.
Materials and Methods: Data was collected from 100 volunteer women in the Cukurova region of Turkey via questionnaire. Multiple computational approaches and statistical tests were used to analyze associated with melasma and environmental factors such as body mass index, sports status, and smoking.
Results: The relationship between the environmental factors (such as body mass index (p<0.001, r=0.47), sports status (p<0.001, r=19.3), and smoking (p<0.001, r=16)) and melasma was found to be significant. Our findings also highlight the potential role of several features like regular medicine intake (p<0.001 r=14), chronic diseases (p=0.001, r=10.2), and water consumption (p<0.001, r=-0.373) in melasma development.
Conclusion: Our study contributes to the literature on the incidence and etiology of melasma in the Cukurova regional population of Turkey. Moreover, this study provides foundational insights for the future development of a machine learning-based classification mechanism to enhance treatment efficiency and patient satisfaction.

Keywords

incidence, facial hyperpigmentation, lifestyle, melasma, etiology

Kadınlarda melazma gelişim sıklığı ve etiyolojisinin anatomik analizi

Abstract

Amaç: Melazma fasiyal hiperpigmentasyondan kaynaklanan, yaşam kalitesini önemli ölçüde etkileyen bir durumdur. Etiyolojisi çok faktörlü olmakla birlikte, ortaya çıkışında yaşam tarzı ve dış faktörler çok önemlidir. Bu çalışmanın temel amacı çevresel faktörler ile melazma görülme sıklığı arasındaki ilişkiyi sayısal olarak ortaya koymaktır. Ayrıca tedavi stratejilerinin optimize edilmesi ve bilgisayarlı tanı araçlarının geliştirilmesine yardımcı olunması da amaçlanmıştır.
Gereç ve Yöntem: Akdeniz bölgesindeki 100 gönüllü kadından anket yoluyla veriler toplandı. Verileri analiz etmek için çoklu hesaplamalı yaklaşımlar ve istatistiksel testler kullanıldı ve vücut kitle indeksi, spor durumu ve sigara içme gibi çevresel faktörlerin melazma ile ilişkisi incelendi.
Bulgular: Çalışmamızda incelediğimiz çevresel faktörler (vücut kitle indeksi (p<0.001, r=0.47), spor durumu (p<0.001, r=19.3) ve sigara içme (p<0.001, r=16) gibi) ve melasma ilişkisi anlamlı bulunmuştur. Bulgularımız aynı zamanda düzenli ilaç alımı (p<0.001 r=14), kronik hastalıklar (p=0.001, r=10.2) ve su tüketimi (p<0.001, r=-0.373) gibi çeşitli özelliklerin melazma gelişimindeki potansiyel rolünü de ortaya koymuştur.
Sonuç: Çalışmamız Akdeniz toplumunda melazmanın görülme sıklığı ve etiyolojisi konusunda literatüre katkı sağlamaktadır. Ayrıca bu çalışma, tedavi verimliliğini ve hasta memnuniyetini artırmak için makine öğrenimine dayalı bir sınıflandırma mekanizmasının gelecekteki gelişimi için temel bilgiler sunmaktadır.

Keywords

etiyoloji, görülme sıklığı, yüz hiperpigmentasyonu, yaşam tarzı, melazma

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