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Comprehensive phytochemical analysis of various extracts of Kickxia lanigera growing in Türkiye

Year 2024, Volume: 7 Issue: 2, 107 - 116
https://doi.org/10.38093/cupmap.1528609

Abstract

In this study, the phytochemical contents of the extracts of Kickxia lanigera plant from Baskil district of Elazığ province in Türkiye obtained in different organic solvents (hexane, chloroform, ethyl acetate and butanol) were determined by spectrometric methods such as GC-MS/FID, ESI-LC-MS/TOF and NMR. The result of GC-MS analysis: palmitic acid (19.08%), oleic acid ( 18.76%), dotriacontane (13.08%), CHCl3; linoleic acid (38.13%), oleic acid (34.08%), palmitic acid (13.79%) were determined in high amounts in hexane. HPLC-TOF/MS analysis showed that the CHCl3 and BuOH extracts had low levels of standard phenols, and the main components in the EA extract (in mg/kg plant) were cinnamic acid (5.92), hesperidin (4.7), apigetrin (4.5) and p-coumaric acid (2.8). the 1H NMR spectrum showed that the CHCl3 and EA extracts were rich in phenols.

Supporting Institution

Çankırı Karatekin University

Project Number

FF0110115D06

References

  • 1. Başar, Y., & Erenler, R. (2024). Phytochemical analysis of Silybum marianum flowers: Quantitative analysis of natural compounds and molecular docking application. Turkish Journal of Biodiversity, 7(1), 20-31. https://doi.org/10.38059/biodiversity.1450643
  • 2. Başar, Y., Yenigün, S., Behçet, L., Ozen, T., & Demirtas, İ. (2024). Antibacterial and Antioxidant Molecule Isolated from Nepeta aristata Boiss Et Kotschy Ex Boiss plant: 1,5,9-Epideoxyloganic Acid. International Journal of Chemistry and Technology, 8(1), 27-31. https://doi.org/10.32571/ijct.1381998
  • 3. Chaouche, M., Demirtaş, İ., Koldaş, S., Tüfekçi, A. R., Gül, F., Özen, T., Wafa, N., Boureghda, A., & Bora, N. (2021). Phytochemical Study and Antioxidant Activities of the Water-Soluble Aerial Parts and Isolated Compounds of Thymus munbyanus subsp. ciliatus (Desf.) Greuter & Burdet. Turk J Pharm Sci, 18(4), 430-437. https://doi.org/10.4274/tjps.galenos.2020.44538
  • 4. Ferrer, C., Malato, O., Agüera, A., & Fernandez-Alba, A. R. (2012). Chapter 1 - Application of HPLC–TOF-MS and HPLC–QTOF-MS/MS for Pesticide Residues Analysis in Fruit and Vegetable Matrices. In A. R. Fernandez-Alba (Ed.), Comprehensive Analytical Chemistry (Vol. 58, pp. 1-60). Elsevier. https://doi.org/https://doi.org/10.1016/B978-0-444-53810-9.00007-9
  • 5. Gül, F., Activity And Isolation Studies On Kickxia Lanigera and K. Spuria Plant Extracts, in Graduate School of Natural and Applied Sciences. 2020, Cankiri Karatekin University. p. 187.
  • 6. Khoddami, A., Wilkes, M. A., & Roberts, T. H. (2013). Techniques for Analysis of Plant Phenolic Compounds. Molecules, 18(2), 2328-2375. https://www.mdpi.com/1420-3049/18/2/2328
  • 7. Marriott, P. J., Shellie, R., & Cornwell, C. (2001). Gas chromatographic technologies for the analysis of essential oils. Journal of Chromatography A, 936(1), 1-22. https://doi.org/https://doi.org/10.1016/S0021-9673(01)01314-0
  • 8. Pinar, M. (1973). 5,6,7-Trimethoxyflavone and 5,6,7,4′-tetramethoxyflavone from Kickxia lanigera. Phytochemistry, 12, 3014-3015.
  • 9. Sahin yaglioglu, A., Eser, F., Yağlioğlu, M., & Demirtas, I. (2020). The antiproliferative and antioxidant activities of the essential oils of Juniperus species from Turkey. Flavour and Fragrance Journal, 35. https://doi.org/10.1002/ffj.3586
  • 10. Yan, Y., Zhang, Q., & Feng, F. (2016). HPLC-TOF-MS and HPLC-MS/MS combined with multivariate analysis for the characterization and discrimination of phenolic profiles in nonfumigated and sulfur-fumigated rhubarb. J Sep Sci, 39(14), 2667-2677. https://doi.org/10.1002/jssc.201501382
  • 11. Yenigün, S., Başar, Y., İpek, Y., Behçet, L., Özen, T., & Demirtaş, İ. (2024). Determination of antioxidant, DNA protection, enzyme inhibition potential and molecular docking studies of a biomarker ursolic acid in Nepeta species. J Biomol Struct Dyn, 42(11), 5799-5816. https://doi.org/10.1080/07391102.2023.2229440
  • 12. Yousefi, N., Zarre, S., & Heubl, G. (2016). Molecular phylogeny of the mainly Mediterranean genera Chaenorhinum, Kickxia and Nanorrhinum (Plantaginaceae, tribe Antirrhineae), with focus on taxa in the Flora Iranica region. Nordic Journal of Botany, 34. https://doi.org/10.1111/njb.01000
Year 2024, Volume: 7 Issue: 2, 107 - 116
https://doi.org/10.38093/cupmap.1528609

Abstract

Project Number

FF0110115D06

References

  • 1. Başar, Y., & Erenler, R. (2024). Phytochemical analysis of Silybum marianum flowers: Quantitative analysis of natural compounds and molecular docking application. Turkish Journal of Biodiversity, 7(1), 20-31. https://doi.org/10.38059/biodiversity.1450643
  • 2. Başar, Y., Yenigün, S., Behçet, L., Ozen, T., & Demirtas, İ. (2024). Antibacterial and Antioxidant Molecule Isolated from Nepeta aristata Boiss Et Kotschy Ex Boiss plant: 1,5,9-Epideoxyloganic Acid. International Journal of Chemistry and Technology, 8(1), 27-31. https://doi.org/10.32571/ijct.1381998
  • 3. Chaouche, M., Demirtaş, İ., Koldaş, S., Tüfekçi, A. R., Gül, F., Özen, T., Wafa, N., Boureghda, A., & Bora, N. (2021). Phytochemical Study and Antioxidant Activities of the Water-Soluble Aerial Parts and Isolated Compounds of Thymus munbyanus subsp. ciliatus (Desf.) Greuter & Burdet. Turk J Pharm Sci, 18(4), 430-437. https://doi.org/10.4274/tjps.galenos.2020.44538
  • 4. Ferrer, C., Malato, O., Agüera, A., & Fernandez-Alba, A. R. (2012). Chapter 1 - Application of HPLC–TOF-MS and HPLC–QTOF-MS/MS for Pesticide Residues Analysis in Fruit and Vegetable Matrices. In A. R. Fernandez-Alba (Ed.), Comprehensive Analytical Chemistry (Vol. 58, pp. 1-60). Elsevier. https://doi.org/https://doi.org/10.1016/B978-0-444-53810-9.00007-9
  • 5. Gül, F., Activity And Isolation Studies On Kickxia Lanigera and K. Spuria Plant Extracts, in Graduate School of Natural and Applied Sciences. 2020, Cankiri Karatekin University. p. 187.
  • 6. Khoddami, A., Wilkes, M. A., & Roberts, T. H. (2013). Techniques for Analysis of Plant Phenolic Compounds. Molecules, 18(2), 2328-2375. https://www.mdpi.com/1420-3049/18/2/2328
  • 7. Marriott, P. J., Shellie, R., & Cornwell, C. (2001). Gas chromatographic technologies for the analysis of essential oils. Journal of Chromatography A, 936(1), 1-22. https://doi.org/https://doi.org/10.1016/S0021-9673(01)01314-0
  • 8. Pinar, M. (1973). 5,6,7-Trimethoxyflavone and 5,6,7,4′-tetramethoxyflavone from Kickxia lanigera. Phytochemistry, 12, 3014-3015.
  • 9. Sahin yaglioglu, A., Eser, F., Yağlioğlu, M., & Demirtas, I. (2020). The antiproliferative and antioxidant activities of the essential oils of Juniperus species from Turkey. Flavour and Fragrance Journal, 35. https://doi.org/10.1002/ffj.3586
  • 10. Yan, Y., Zhang, Q., & Feng, F. (2016). HPLC-TOF-MS and HPLC-MS/MS combined with multivariate analysis for the characterization and discrimination of phenolic profiles in nonfumigated and sulfur-fumigated rhubarb. J Sep Sci, 39(14), 2667-2677. https://doi.org/10.1002/jssc.201501382
  • 11. Yenigün, S., Başar, Y., İpek, Y., Behçet, L., Özen, T., & Demirtaş, İ. (2024). Determination of antioxidant, DNA protection, enzyme inhibition potential and molecular docking studies of a biomarker ursolic acid in Nepeta species. J Biomol Struct Dyn, 42(11), 5799-5816. https://doi.org/10.1080/07391102.2023.2229440
  • 12. Yousefi, N., Zarre, S., & Heubl, G. (2016). Molecular phylogeny of the mainly Mediterranean genera Chaenorhinum, Kickxia and Nanorrhinum (Plantaginaceae, tribe Antirrhineae), with focus on taxa in the Flora Iranica region. Nordic Journal of Botany, 34. https://doi.org/10.1111/njb.01000
There are 12 citations in total.

Details

Primary Language English
Subjects Plant Biochemistry, Pharmaceutical Biochemistry
Journal Section Research Articles
Authors

Fatih Gül 0000-0002-4297-786X

Yunus Başar 0000-0002-7785-3242

İbrahim Demirtas 0000-0001-8946-647X

Lütfi Behçet 0000-0001-8334-7816

Project Number FF0110115D06
Early Pub Date November 3, 2024
Publication Date
Submission Date August 5, 2024
Acceptance Date September 22, 2024
Published in Issue Year 2024 Volume: 7 Issue: 2

Cite

APA Gül, F., Başar, Y., Demirtas, İ., Behçet, L. (2024). Comprehensive phytochemical analysis of various extracts of Kickxia lanigera growing in Türkiye. Current Perspectives on Medicinal and Aromatic Plants, 7(2), 107-116. https://doi.org/10.38093/cupmap.1528609

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