Case Report
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Year 2022, , 124 - 127, 29.10.2022
https://doi.org/10.56016/dahudermj.1167707

Abstract

References

  • Boivin G, Abed Y, Pelletier G, et al. Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. J Infect Dis 2002; 186:1330.
  • Wolf DG, Zakay-Rones Z, Fadeela A, Greenberg D, Dagan R. 2003. High seroprevalence of human metapneumovirus among young children in Israel. J Infect Dis 188:1865–1867.
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  • Nickbakhsh S, Mair C, Matthews L, et al. Virus–virus interactions impact the population dynamics of influenza and the common cold. Proc Natl Acad Sci USA. 2019;116(52): 27142–27150.
  • Walsh EE, Peterson DR, Falsey AR. Human metapneumovirus infections in adults: another piece of the puzzle. Arch Intern Med. 2008;168(22):2489–2496.
  • Falsey AR, Erdman D, Anderson LJ, et al. Human metapneumovirus infections in young and elderly adults. J Infect Dis. 2003;187(5):785–790.
  • Zhu J, Ji P, Pang J, et al. Clinical characteristics of COVID-19 patients: a meta-analysis. J Med Virol. 2020;3:62.
  • Li LQ, Huang T, Wang YQ, et al. COVID-19 patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol. 2020;92(9):1433–1433.
  • Jongbloed, M., Leijte, W. T., Linssen, C. F. M., van den Hoogen, B. G., van Gorp, E. C. M., & de Kruif, M. D. (2021). Clinical impact of human metapneumovirus infections before and during the COVID-19 pandemic. Infectious Diseases, 2021 Jul;53(7):488-497
  • Koo HJ, Lee HN, Choi SH, et al. Clinical and radiologic characteristics of human metapneumovirus infections in adults. Emerg Infect Dis. 2019;25(1):15–24.
  • Loubet P, Methieu P, Lenzi N, et al. Characteristics of human metapneumovirus infection in adults hospitalized for community-acquired influenza-like illness in France, 2012-2018: a retrospective observational study. Clin Microbiol Infect. 2020;27(1):30190–30197.
  • Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229):1054–1062.
  • Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
  • Lim YK, Kweon OJ, Kim HR, et al. Clinical features, epidemiology, and climatic impact of genotype-specific human metapneumovirus infections: long-term surveillance of hospitalized patients in South Korea. Clin Infect Dis. 2019; 70(12):ciz697.
  • Rodriguez-Morales AJ, Cardona-Ospina JA, Guti errezOcampo E, et al. Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis. 2020; 34:101623. [27] Guan W, Ni Z, Hu Y, China Medical
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  • Li X, Xu S, Yu M, et al. Risk factors for severity and mortality in adult COVID-19 in patients in Wuhan. J Allergy Clin Immunol. 2020;146(1):110–118.
  • Kang YJ. Mortality rate of infection with COVID-19 in Korea from the perspective of underlying disease. Disaster Med Public Health Prep. 2020;14(3):1–3
  • Koo HJ, Lee HN, Choi SH, et al. Clinical and radiologic characteristics of human metapneumovirus infections in adults. Emerg Infect Dis. 2019;25(1):15–24
  • Koo HJ, Lim S, Choi SH, et al. Radiographic and CT features of viral pneumonia. Radiographics. 2018;38(3):719–739.
  • Keske S¸, Gum€ us €¸ T, Koymen T, et al. € O. Human metapneumovirus infection: diagnostic impact of radiologic imaging. J Med Virol. 2019;91(6):958–962.
  • Li K, Wu J, Wu F, et al. The clinical and chest CT features associated with severe and critical COVID-19 Pneumonia. Invest Radiol. 2020;55(6):327–331.

Human Metapneumovirus Pneumonia During The Sars Cov-2 Pandemic

Year 2022, , 124 - 127, 29.10.2022
https://doi.org/10.56016/dahudermj.1167707

Abstract

Human metapneumovirus (HMPV) is a virus from the paramyxovirus family identified in 2001. It is the second most common cause of lower respiratory tract infection in children after respiratory syncytial virus. In adults, it is mostly seen in the elderly population, immunosuppressive patients or those with a concomitant chronic disease. Human metapnemovirus can cause various clinical pictures ranging from a simple upper respiratory tract infection to bronchiolitis and asthma attack, from severe pneumonia to encephalitis and acute respiratory distress syndrome. In the case of viral infection in adults, especially during the Covid-19 pandemic, clinical and laboratory findings are similar, so it should be kept in mind in the differential diagnosis. This article is presented to draw attention to the inclusion of HMPV in the differential diagnosis of a 65-year-old female patient who applied to the practice with the complaints of high fever, cough, wheezing and headache during the Covid-19 pandemic. It has become important to detect the causative agent with multiple molecular tests and direct antigen tests in terms of differential diagnosis in respiratory tract infections, which are generally seen in adults during the pandemic. After the viral agent is determined with the diagnosis of the causative agent, the infection can be controlled more easily with the right treatment and the unnecessary use of antibiotics can be prevented.

References

  • Boivin G, Abed Y, Pelletier G, et al. Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. J Infect Dis 2002; 186:1330.
  • Wolf DG, Zakay-Rones Z, Fadeela A, Greenberg D, Dagan R. 2003. High seroprevalence of human metapneumovirus among young children in Israel. J Infect Dis 188:1865–1867.
  • Aksoy Gökmen A, Çiçek C. Yeni bulunan eski solunum virüsü: human metapneumovirus. Ege Tıp Dergisi 2014;53:112-118.
  • Nickbakhsh S, Mair C, Matthews L, et al. Virus–virus interactions impact the population dynamics of influenza and the common cold. Proc Natl Acad Sci USA. 2019;116(52): 27142–27150.
  • Walsh EE, Peterson DR, Falsey AR. Human metapneumovirus infections in adults: another piece of the puzzle. Arch Intern Med. 2008;168(22):2489–2496.
  • Falsey AR, Erdman D, Anderson LJ, et al. Human metapneumovirus infections in young and elderly adults. J Infect Dis. 2003;187(5):785–790.
  • Zhu J, Ji P, Pang J, et al. Clinical characteristics of COVID-19 patients: a meta-analysis. J Med Virol. 2020;3:62.
  • Li LQ, Huang T, Wang YQ, et al. COVID-19 patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol. 2020;92(9):1433–1433.
  • Jongbloed, M., Leijte, W. T., Linssen, C. F. M., van den Hoogen, B. G., van Gorp, E. C. M., & de Kruif, M. D. (2021). Clinical impact of human metapneumovirus infections before and during the COVID-19 pandemic. Infectious Diseases, 2021 Jul;53(7):488-497
  • Koo HJ, Lee HN, Choi SH, et al. Clinical and radiologic characteristics of human metapneumovirus infections in adults. Emerg Infect Dis. 2019;25(1):15–24.
  • Loubet P, Methieu P, Lenzi N, et al. Characteristics of human metapneumovirus infection in adults hospitalized for community-acquired influenza-like illness in France, 2012-2018: a retrospective observational study. Clin Microbiol Infect. 2020;27(1):30190–30197.
  • Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229):1054–1062.
  • Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
  • Lim YK, Kweon OJ, Kim HR, et al. Clinical features, epidemiology, and climatic impact of genotype-specific human metapneumovirus infections: long-term surveillance of hospitalized patients in South Korea. Clin Infect Dis. 2019; 70(12):ciz697.
  • Rodriguez-Morales AJ, Cardona-Ospina JA, Guti errezOcampo E, et al. Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis. 2020; 34:101623. [27] Guan W, Ni Z, Hu Y, China Medical
  • Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229):1054–1062.
  • Li X, Xu S, Yu M, et al. Risk factors for severity and mortality in adult COVID-19 in patients in Wuhan. J Allergy Clin Immunol. 2020;146(1):110–118.
  • Kang YJ. Mortality rate of infection with COVID-19 in Korea from the perspective of underlying disease. Disaster Med Public Health Prep. 2020;14(3):1–3
  • Koo HJ, Lee HN, Choi SH, et al. Clinical and radiologic characteristics of human metapneumovirus infections in adults. Emerg Infect Dis. 2019;25(1):15–24
  • Koo HJ, Lim S, Choi SH, et al. Radiographic and CT features of viral pneumonia. Radiographics. 2018;38(3):719–739.
  • Keske S¸, Gum€ us €¸ T, Koymen T, et al. € O. Human metapneumovirus infection: diagnostic impact of radiologic imaging. J Med Virol. 2019;91(6):958–962.
  • Li K, Wu J, Wu F, et al. The clinical and chest CT features associated with severe and critical COVID-19 Pneumonia. Invest Radiol. 2020;55(6):327–331.
There are 22 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Serap Çetiner 0000-0002-0846-5908

Özgür Okuturlar 0000-0003-2297-7464

Özlem Kaplan 0000-0001-6309-2158

Publication Date October 29, 2022
Submission Date August 27, 2022
Published in Issue Year 2022

Cite

EndNote Çetiner S, Okuturlar Ö, Kaplan Ö (October 1, 2022) Human Metapneumovirus Pneumonia During The Sars Cov-2 Pandemic. DAHUDER Medical Journal 2 4 124–127.



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