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Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study

Year 2016, Volume: 43 Issue: 4, 556 - 560, 25.12.2016
https://doi.org/10.5798/diclemedj.0921.2015.01.0521

Abstract


Objectives: In our study, the assessment of age,
gender, incidence and seasonal differences in the regions related to
appendicitis were investigated.


Methods: 676 patients that received an operation
following a diagnosis of appendicitis in 3 hospitals from 3 different
regions of Turkey occurring at different dates were examined
retrospectively after being categorized by region. The differences among
groups were compared to each.


Results: The mean age of male (63%) (n = 426) and
female (37%) (n = 250) patients (total = 676) was 10.8 years (range,
1–18 years). The percentage of female patients in the The Black Sea
Region (BR) group was significantly higher (48%) than that in the other
two groups (%33 for SR, 30% for MR) (P = 0.001). The frequency of
appendicitis was higher (36%) in the spring and winter (25%) than that
during summer or fall. The number of cases increased the most in the BR
group in spring (47%) (P < 0.001). When the types of appendicitis in
the different age groups were compared with season, acute appendicitis
(P < 0.02) was more frequently (93%) seen in the child-adolesan (CA)
group in the spring; however, perfore apandicitis (45%) was greater in
the Infant-Preschool (IPS) group (P < 0.02). Acute appendicitis
comprised 55% and perforated appendicitis comprised 45% of cases in the
IPS group, whereas acute appendicitis comprised 78% and perforated
appendicitis comprised 22% in the CA group.


Conclusion: According to the results of our study,
appendicitis was most frequently seen in the spring and winter seasons
and more frequent in boys between the ages of 10-13 years. As age
decreases, the frequency of perforated appendicitis increases.
Appendicitis is affected by environmental factors. Reducing the
incidence of appendicitis may be possible by establishing regional and
specific studies related to this subject and the etiologies of the
disease.

References

  • 1. Yıldız T, Bozdağ Z, Erkorkmaz U, et al. Analysis of riskfactors for the development of pediatric appendicitis. Ulus Travma Acil Cerrahi Derg 2013;19:554-8.
  • 2. Oguntola AS, Adeoti ML, Oyemolade TA. Appendicitis: Trends in incidence, age, sex, and seasonal variations in South Western Nigeria.
  • Ann Afr Med 2010;9:213-7.
  • 3. Al Omran M, Mamdani M, McLeod RS. Epidemiologic features of acute appendicitis in Ontario, Canada. Can J Surg 2003;46:263-8.
  • 4. Başaklar AC, Türkyılmaz Z. Karın agrisi ve akut apandisit, In: Başaklar AC (ed), Bebek ve Çocukların Cerrahi ve Ürolojik Hastalıkları. Palme Yayıncılık, Ankara, 2006;pp:991-1013.
  • 5. Sulu B, Günerhan Y, Palanci Y, Işler B, Cağlayan K. Epidemiological and demographic features of appendicitis and influences of several environmental factors. Ulus Travma Acil Cerrahi Derg 2010;16:38-42.
  • 6. Yazici M, Ozkisacik S, Oztan MO, Gürsoy H. Neutrophil/lymphocyte ratio in the diagnosis of childhood appendicitis. Turk J ediatr 2010;524:400-3.
  • 7. Noh H, Chang SJ, Han A. The diagnostic values of preoperative laboratory markers in children with complicated appendicitis. J Korean Surg Soc 2012;834:237-41.
  • 8. Kapischke M, Pries A, Caliebe A. Short term and long term results after open vs. laparoscopic appendectomy in childho and adolescence: a subgroup analysis. BMC Pediatr 2013;13:154.
  • 9. Stein GY, Rath Wolfson L, Zeidman A, et al. Seasonal and day of the week variations of perforated appendicitis in US children. Pediatr Surg Int 2010;26:691-6.
  • 10. Lee JH, Park YS, Choi JS. The epidemiology of appendicitis and appendectomy in South Korea: national registry data. J Epidemiol 2010;20:97-105.
  • 11. Luckmann R, Davis P. The epidemiology of acute appendicitis in California: racial, gender, and seasonal variation. Epidemiology 1991;2:323-30.
  • 12. Choi JY, Ryoo E, Jo JH, et al. Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis. Korean J Pediatr. 2016;59:368-73.
  • 13. Günşar C, Karaca İ, Ceylan H, et al. Sex differences in the epidemiology, seasonal variation, and trends in the management of patients with acute appendicitis. Langenbecks Arch Surg 2012;397:1087-92.
  • 14. Salö M, Ohlsson B, Arnbjörnsson E, Stenström P. Appendicitis in children from a gender perspective. Pediatr Surg Int. 2015;31:845-53.
  • 15. Curran TJ, Muenchow SK. The treatment of complicated appendicitis in children using peritoneal drainage: results from a public hospital. J Pediatr Surg 1993;28:204-8.
  • 16. Neilson IR, Laberge JM, Nguyen LT, et al. Appendicitis in children: current therapeutic recommendations. J Pediatr Surg 1990;25:1113-16.
  • 17. Günşar C, Karaca İ, Ceylan H, et al. Diagnostic values of ultrasonographic criteria in the diagnosis of childhood acute and perforated appendicitis. Akademik Gastroenteroloji Dergisi 2004;3:88-92.
Year 2016, Volume: 43 Issue: 4, 556 - 560, 25.12.2016
https://doi.org/10.5798/diclemedj.0921.2015.01.0521

Abstract

References

  • 1. Yıldız T, Bozdağ Z, Erkorkmaz U, et al. Analysis of riskfactors for the development of pediatric appendicitis. Ulus Travma Acil Cerrahi Derg 2013;19:554-8.
  • 2. Oguntola AS, Adeoti ML, Oyemolade TA. Appendicitis: Trends in incidence, age, sex, and seasonal variations in South Western Nigeria.
  • Ann Afr Med 2010;9:213-7.
  • 3. Al Omran M, Mamdani M, McLeod RS. Epidemiologic features of acute appendicitis in Ontario, Canada. Can J Surg 2003;46:263-8.
  • 4. Başaklar AC, Türkyılmaz Z. Karın agrisi ve akut apandisit, In: Başaklar AC (ed), Bebek ve Çocukların Cerrahi ve Ürolojik Hastalıkları. Palme Yayıncılık, Ankara, 2006;pp:991-1013.
  • 5. Sulu B, Günerhan Y, Palanci Y, Işler B, Cağlayan K. Epidemiological and demographic features of appendicitis and influences of several environmental factors. Ulus Travma Acil Cerrahi Derg 2010;16:38-42.
  • 6. Yazici M, Ozkisacik S, Oztan MO, Gürsoy H. Neutrophil/lymphocyte ratio in the diagnosis of childhood appendicitis. Turk J ediatr 2010;524:400-3.
  • 7. Noh H, Chang SJ, Han A. The diagnostic values of preoperative laboratory markers in children with complicated appendicitis. J Korean Surg Soc 2012;834:237-41.
  • 8. Kapischke M, Pries A, Caliebe A. Short term and long term results after open vs. laparoscopic appendectomy in childho and adolescence: a subgroup analysis. BMC Pediatr 2013;13:154.
  • 9. Stein GY, Rath Wolfson L, Zeidman A, et al. Seasonal and day of the week variations of perforated appendicitis in US children. Pediatr Surg Int 2010;26:691-6.
  • 10. Lee JH, Park YS, Choi JS. The epidemiology of appendicitis and appendectomy in South Korea: national registry data. J Epidemiol 2010;20:97-105.
  • 11. Luckmann R, Davis P. The epidemiology of acute appendicitis in California: racial, gender, and seasonal variation. Epidemiology 1991;2:323-30.
  • 12. Choi JY, Ryoo E, Jo JH, et al. Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis. Korean J Pediatr. 2016;59:368-73.
  • 13. Günşar C, Karaca İ, Ceylan H, et al. Sex differences in the epidemiology, seasonal variation, and trends in the management of patients with acute appendicitis. Langenbecks Arch Surg 2012;397:1087-92.
  • 14. Salö M, Ohlsson B, Arnbjörnsson E, Stenström P. Appendicitis in children from a gender perspective. Pediatr Surg Int. 2015;31:845-53.
  • 15. Curran TJ, Muenchow SK. The treatment of complicated appendicitis in children using peritoneal drainage: results from a public hospital. J Pediatr Surg 1993;28:204-8.
  • 16. Neilson IR, Laberge JM, Nguyen LT, et al. Appendicitis in children: current therapeutic recommendations. J Pediatr Surg 1990;25:1113-16.
  • 17. Günşar C, Karaca İ, Ceylan H, et al. Diagnostic values of ultrasonographic criteria in the diagnosis of childhood acute and perforated appendicitis. Akademik Gastroenteroloji Dergisi 2004;3:88-92.
There are 18 citations in total.

Details

Journal Section Research Articles
Authors

Serkan Arslan

Bahattin Aydogdu This is me

Mehmet Serif Arslan This is me

Hikmet Zeytun This is me

Mehmet Hanifi Okur This is me

Erol Basuguy This is me

Ali Erdal Karakaya This is me

Ibrahim Uygun This is me

Selcuk Otcu This is me

Publication Date December 25, 2016
Submission Date January 11, 2017
Published in Issue Year 2016 Volume: 43 Issue: 4

Cite

APA Arslan, S., Aydogdu, B., Arslan, M. S., Zeytun, H., et al. (2016). Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study. Dicle Tıp Dergisi, 43(4), 556-560. https://doi.org/10.5798/diclemedj.0921.2015.01.0521
AMA Arslan S, Aydogdu B, Arslan MS, Zeytun H, Okur MH, Basuguy E, Karakaya AE, Uygun I, Otcu S. Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study. diclemedj. December 2016;43(4):556-560. doi:10.5798/diclemedj.0921.2015.01.0521
Chicago Arslan, Serkan, Bahattin Aydogdu, Mehmet Serif Arslan, Hikmet Zeytun, Mehmet Hanifi Okur, Erol Basuguy, Ali Erdal Karakaya, Ibrahim Uygun, and Selcuk Otcu. “Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study”. Dicle Tıp Dergisi 43, no. 4 (December 2016): 556-60. https://doi.org/10.5798/diclemedj.0921.2015.01.0521.
EndNote Arslan S, Aydogdu B, Arslan MS, Zeytun H, Okur MH, Basuguy E, Karakaya AE, Uygun I, Otcu S (December 1, 2016) Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study. Dicle Tıp Dergisi 43 4 556–560.
IEEE S. Arslan, B. Aydogdu, M. S. Arslan, H. Zeytun, M. H. Okur, E. Basuguy, A. E. Karakaya, I. Uygun, and S. Otcu, “Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study”, diclemedj, vol. 43, no. 4, pp. 556–560, 2016, doi: 10.5798/diclemedj.0921.2015.01.0521.
ISNAD Arslan, Serkan et al. “Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study”. Dicle Tıp Dergisi 43/4 (December 2016), 556-560. https://doi.org/10.5798/diclemedj.0921.2015.01.0521.
JAMA Arslan S, Aydogdu B, Arslan MS, Zeytun H, Okur MH, Basuguy E, Karakaya AE, Uygun I, Otcu S. Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study. diclemedj. 2016;43:556–560.
MLA Arslan, Serkan et al. “Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study”. Dicle Tıp Dergisi, vol. 43, no. 4, 2016, pp. 556-60, doi:10.5798/diclemedj.0921.2015.01.0521.
Vancouver Arslan S, Aydogdu B, Arslan MS, Zeytun H, Okur MH, Basuguy E, Karakaya AE, Uygun I, Otcu S. Analysis of Risk Factors for Appendicitis in Children: A Multicenter Epidemiological Study. diclemedj. 2016;43(4):556-60.