Kolonoskopi Yapılan Hastalarda Kolonik Divertikülozis Oranı ve İlişkili Faktörler

Year 2024, Volume: 26 Issue: 1, 9 - 14, 30.04.2024

Nik Ahmad Amru Nik Mazlan , Ahmad Shanwani Mohamed Sidek , Andee Dzulkarnaen Zakaria , Zaıdı Zakarıa , Maya Mazuwin Yahya , Wan Zainira Wan Zain , Mung Seong Wong , Siti Rahmah Hashim Merican , Mohd Nizam Md Hashim , Ikhwan Sani Mohamad , Wan Mohd Mokhzani Wan Mohd Mokhter , Zalına Zaharı , Michael Pak-kai Wong

https://doi.org/10.18678/dtfd.1374820

Abstract

Amaç: Divertiküler hastalık bugüne kadar en sık görülen gastrointestinal hastalıklardan biridir ve gelişmekte olan ülkelerde belirgin bir artış eğilimi göstermektedir. Ancak kolonoskopi yapılan hastalarda kolonik divertikülozis oranı ve bununla ilişkili faktörler tartışmalıdır. Bu çalışmada, toplumdaki divertiküler hastalık oranına ilişkin yerel verilerin, komplikasyonları, divertikülozisin demografik özelliklerin yanı sıra diyabet ve hipertansiyon ile ilişkisinin de incelenmesi amaçlandı.
Gereç ve Yöntemler: Ocak ve Aralık 2019 tarihleri arasında kolonoskopi yapılan hastaların tıbbi kayıtları geriye dönük olarak incelendi. Demografik ve klinik özellikler, diyabet, hipertansiyon ve divertiküler hastalık varlığı ve komplikasyonları incelendi ve divertiküler hastalık ve komplikasyonlarının demografik ve klinik özellikler ile ilişkisi analiz edildi.
Bulgular: 221 hastanın %12,7'sinde (n=28) divertiküler hastalıklar mevcuttu ve hafif baskın olarak sağ tarafta (%42,9, n=12) görülüyordu. Yaş (p=0,002), etnik köken (p=0,011) ve hipertansiyon (p=0,036) ile anlamlı ilişki vardı, ancak cinsiyet ve diyabet ile anlamlı ilişki yoktu (sırasıyla p=0,261 ve p=0,334). Hipertansiyon ile komplike divertikülit nüksü (p=0,741), septik komplikasyonlar (p=0,678) ve divertiküler kanama (p=0,243) arasında anlamlı bir ilişki saptanmadı. Diabetes Mellitus'un divertiküler kanama komplikasyonları (p=0,001) ile anlamlı düzeyde ilişkili olduğu ancak septik komplikasyonlar (p=0,418) ve komplike divertikülit nüksü (p=0,629) ile ilişkili olmadığı görüldü.
Sonuç: Bu çalışma önceki yerel çalışmalarla karşılaştırıldığında neredeyse benzer bir divertikülozis yüzdesi gösterdi. Yaş, etnik köken ve hipertansiyon divertikülozis varlığıyla, diyabet ise divertiküler kanamayla ilişkiliydi.

Keywords

Divertiküler hastalık, yaş, etnik köken, hipertansiyon, diyabet

Proportion of Colonic Diverticulosis and Its Associated Factors among Patients Underwent Colonoscopy

Abstract

Aim: Diverticular disease is one of the most common gastrointestinal disorders to date, with a notable rising trend in developing countries. However, the proportion of colonic diverticulosis and its associated factors among patients who have undergone colonoscopy remains controversial. This study aimed to determine the local data on the proportion of diverticular disease in the community, its complications, the association of diverticulosis with diabetes mellitus and hypertension, as well as demographic characteristics.
Material and Methods: A retrospective review of medical records was performed among patients who had undergone colonoscopy between January and December 2019. Demographic and clinical characteristics, the presence of diabetes mellitus, hypertension, and diverticular disease and its complications were examined, and the association of diverticular disease and its complications with demographic and clinical characteristics were analyzed.
Results: Out of 221 patients, 12.7% (n=28) of them had diverticular diseases with a slightly predominant right-sided occurrence (42.9%, n=12). There were significant associations with age (p=0.002), ethnicity (p=0.011), and hypertension (p=0.036), but not with gender and diabetes mellitus (p=0.261, and p=0.334, respectively). There was no significant association between hypertension and recurrence of complicated diverticulitis (p=0.741), septic complications (p=0.678), and diverticular bleeding (p=0.243). Diabetes mellitus was significantly associated with diverticular bleeding complications (p=0.001) but not with septic complications (p=0.418) and recurrence of complicated diverticulitis (p=0.629).
Conclusion: This study showed almost a similar percentage of diverticulosis compared to previous local studies. Age, ethnicity, and hypertension were associated with the presence of diverticulosis, and diabetes mellitus was associated with diverticular bleeding.

Keywords

Diverticular disease, age, ethnicity, hypertension, diabetes mellitus

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