Investigation on the effectiveness of mastitis vaccine (Startvac®) in sheep and goat gangrenous mastitis cases caused by Staphylococcus aureus

Year 2017, Volume: 10 Issue: 2, 107 - 114, 25.12.2017

Simten Yeşilmen , Nurettin Işık , Nihat Özyurtlu , İbrahim Küçükaslan Zafer Cantekin Yaşar Ergün

Abstract

Mastitis is the inflammatory reaction of the udder to bacterial, chemical, thermal and mechanical effects. It causes significant production losses.  The purpose of this study is to determine the effectiveness of Startvac^® (Hipra), vaccine in sheep and goats with gangrenous mastitis caused by Staphylococcus aureus. The research sample consisted of eight sheep and four goats. The sheep and goats were divided into two groups. The first group was administered classical treatment procedure (parenteral and intramammary antibiotics with nonsteroidal anti-inflammatory drug).  In the second group, 1 ml Startvac^® vaccine was used with classical treatment procedure. Patients returned to normal in the first group after 48 hours, although lactation ceased on day six and hardness was detected in the udder tissue. On day 10 of treatment, the clinical findings of the animals returned to normal, although the milk yield was much lower when compared to the other treatment group. The clinical appearance of in Group 2 returned to normal after 48 hours, and the animals recovered on Day 6 of treatment. On Day 10, the clinical symptoms disappeared and milk yield increased significantly compared to Group 1. It was concluded that Startvac^® mastitis vaccine could increase treatment success in gangrenous mastitis cases in sheep and goats when administered in addition to the classical clinical treatment. 

Keywords

Gangrenous mastitis, mastitis vaccine, small ruminant

Koyun ve keçilerde Staphylococcus aureus kaynaklı gangrenli mastitis olgularında mastitis aşısının (Startvac®) etkinliğinin araştırılması

Abstract

Mastitis;
memenin bakteriyel, kimyasal, termal ve mekanik etkilere verdiği yangısal
reaksiyondur. Önemli üretim kaybına neden olur. Bu çalışmanın amacı; Staphylococcus
aureus kaynaklı kangrenli
mastitisli koyun ve keçilerde Startvac^® (Hipra) aşısının etkinliğini
belirlemektir. Araştırma materyalini sekiz koyun ve dört keçi oluşturmaktadır.
Koyun ve keçiler iki gruba ayrıldı. İlk gruba klasik tedavi prosedürü
(parenteral ve meme içi antibiyotik tedavisi ile birlikte nonsteroidal
antienflamatuar ilaç), ikinci grupta klasik tedavi ile birlikte 1 ml Startvac^®
aşısı uygulandı. İlk grupta her ne kadar 6. günde laktasyon durmuş ve meme
lobunda sertlik oluşmuşsa da hastalar 48 saat sonrasında normale döndü.
Tedavinin 10. gününde süt verimi diğer tedavi grubuna göre daha az olmasının
yanı sıra hayvanların klinik bulguları normale döndü. Grup 2 de klinik görünüm
48. saatte normale döndü ve tedavinin 6. gününde iyileştiler. Onuncu günde klinik
semptomlar yok oldu ve süt verimi Grup 1’e göre önemli düzeyde arttı. Koyun ve
keçilerde kangrenli mastitis olgularında klasik tedaviye ek olarak uygulanan
Startvac^® mastitis aşısının tedavi başarısını arttırabileceği
sonucuna varılmıştır.

Keywords

Gangrenöz mastitis, mastitis aşısı, küçük ruminant

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