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Endometrial patolojilerin araştırılmasında iki endometrial biyopsi tekniğinin araştırılması

Year 2019, Volume: 2 Issue: 1, 26 - 30, 01.04.2019
https://doi.org/10.33713/egetbd.458304

Abstract

Amaç: Bu çalışmanın amacı, endometriyal patolojilerin tanısında histeroskopik
endometriyal biyopsi (H / S) ve prob kürtajının (P / C) tanısal performansını
karşılaştırmaktır.



Gereç ve Yöntemler: Çalışmamız Aralık 2010-Temmuz 2011 tarihleri
​​arasında üçüncü basamak doğum ve jinekoloji kliniğinde yapıldı. Prospektif
çalışmalarımızda, değerlendirmeler için kliniğimize başvuran 83 hastaya H / S
ve P / C biyopsilerinin histopatolojik sonuçları Endometriyum incelendi ve
kombine prosedürle (H / S ve P / C) karşılaştırıldı.



Bulgular: Histopatolojik sonuçlar; endometriyal polipler (% 48),
endometrial hiperplazi (% 13.2), submukoz myoma (% 4.8), endometrial kanser (%
4.8) ve normal endometriyal doku (% 28.9) idi. Endometriyal polip, submüköz
myom, endometriyal hiperplazi ve endometriyal kanser için H / S biyopsisi ile
biyopsi ve biyopsi ile biyopsi duyarlılık değerleri% 97.5 vs% 54,6,% 100 vs%
25,% 75 olarak bulundu. Sırasıyla% 100 ve% 63.6 ve% 100.



Sonuç: H / S, endometriyal polip ve submüköz myoma gibi fokal lezyonların tanısında
P / C'den daha üstündür. Endometriyal hiperplazi ve endometriyal kanser gibi
yaygın lezyonların teşhisi için hiçbir müdahalenin diğerinden istatistiksel
olarak üstün olmadığını saptadık.

References

  • 1. Lessey BA, Killam AP,Metzger DA. Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. J Clin Endocrinol Metab 1998;67:334-9.2. Fleischer AC, Gordon AN, Entman SS, et al: Transvaginal Scanning of the Endometriyum: Current and Potential Clinical Applications. In Fleischer AC, Romero R, Manning F (Eds): The Principles and Practice of Ultrasonography in Obstetrics and Gynecology. Norwalk, CT, Appleton and Lange, 1991.3. Marret H, Fauconnier A, Chabbert-Buffet N, Cravello L. Clinical practice guidelines on menoorhagia: management of abnormal uterine bleeding before menopause Eur J Obstet Gynecol Reprod Biol 2010;152:133-7.4. De Vries LD, Dijkhuizen FP, Mol BW, Brolmann HA, Moret E, Heintz AP. Comparison of transvaginal sonography, saline infusion sonography, and hysteroscopy in premenopausal women with abnormal uterine bleeding. J Clin Ultrasound 2000;28:217-23.5. Motashaw ND, Dave S. Diagnostic and therapeutic hysteroscopy in the management of abnormal uterine bleeding. J Reprod Med 1990;3:616-20.6. Hoo YC, Mak BS, Hsu C, Wong TS, Ma HK. Postmenopausal uterine bleeding of nonorganic cause. Obstet Gynecol 1985;66:225-8.7. Parulaker SU. Significance of negative hysteroscopic view in abnormal uterine bleeding. J Postgrad Med 1992;38:62-4. 8. Emanuel MH, Verdel MJ, Wamsteker K, Lammes FB. A prospective comparison of transvaginal US and diagnostic hysteroscopy in the evaluation of patients with abnormal uterine bleeding: clinical implications. Am J Obstet Gynecol 1995;172:547-52.9. Cronje HS. Diagnostic hysteroscopy after postmenopausal uterine bleeding. S Afr Med J 1984;66:773-4. 10. Garutti G, Sambruni I, Cellani F, Garzia D, Alleva P, Luerti M. Hysteroscopy and transvaginal ultrasonography in postmenopausal women with uterine bleeding. Int J Gynecol Obstet 1999;65:25-33. 11. Mencaglia L, Vale RF, Perino A, Gilardi G.. Endometriyal carcinoma and its precursors: Early detection and treatment. Int J Gynekol Obstet 1990;31:107-16.12. Hidlebaugh D. A comparison of clinical outcomes and cost of office versus hospital hysteroscopy. J Am Assoc Gynecol Laparosc 1996;4:39-45. 13. Gimpleson R. Office hysteroscopy. Clin Obstet Gynecol 1992;35:270-81. 14. Goldstein SR. Incorporating endovaginal ultrasonography into the overall gynecologic examination. Am J Obstet Gynecol 1990;162:625-32. 15. Crescini C, Artuso A, Repetti F, Reale D, Pezzica E. Hysteroscopic diagnosis in patients with abnormal uterine hemorrhage and previous endometriyal curettage. Minerva Ginecol 1992;44:233-5. 16. Maia H Jr, Barbosa IC, Farias JP, Ladipo OA, Coutinho EM. Evaluation of the endometriyal cavity during menopause. Int J Gynaecol Obstet 1996;52:61-6. 17. Madan SM, Al-Jufairi ZA. Abnormal uterine bleeding. Diagnostic value of hysteroscopy. Saudi Med J 2001;22:153-6. 18. Svirsky R, Smorgick N, Rozowsky U, Sagiv R. Can we rely on blind endometrial biopsy for detection of focal intrauterine pathology? Am J Obstet Gynecol 2008;199:1-3.

The comparison of two endometrial biopsy techniques in detection of endometrial pathologies

Year 2019, Volume: 2 Issue: 1, 26 - 30, 01.04.2019
https://doi.org/10.33713/egetbd.458304

Abstract

Objective: The purpose
of this study is to compare the diagnostic performance of hysteroscopic
endometrial biopsy (H/S) and probe curettage (P/C) in the diagnosis of
endometrial pathologies.

Material and
Methods:
Our study was conducted at a tertiary obstetrics and
gynecology clinic between December 2010 and July 2011. In our prospective
study, histopathological results of both biopsies with H/S and P/C applied to
83 patients admitted to our clinic for evaluation of endometrium, were examined
and compared with combine procedure (H/S and P/C).

Results:  Histopathological results were as
follows: endometrial polyps (48%), endometrial hyperplasia (13.2%), submucous
myoma (4.8%), endometrial cancer (4.8%), and normal endometrial tissue (28.9%). Sensitivity values of biopsy with H/S versus
biopsy with P/C for the endometrial polyp, submucous myoma, endometrial
hyperplasia and endometrial cancer were found as 97.5% vs. %54,6, 100% vs.%25 ,
75% vs. %100 and 63.6% vs. %100, respectively.







Conclusion: H/S was apparently
superior to P/C in diagnosis of focal lesions such as endometrial polyps and
submucous myoma. We determined none of the interventions to be statistically
superior to the other in diagnosis of diffuse lesions such as endometrial
hyperplasia and endometrial cancer. 

References

  • 1. Lessey BA, Killam AP,Metzger DA. Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. J Clin Endocrinol Metab 1998;67:334-9.2. Fleischer AC, Gordon AN, Entman SS, et al: Transvaginal Scanning of the Endometriyum: Current and Potential Clinical Applications. In Fleischer AC, Romero R, Manning F (Eds): The Principles and Practice of Ultrasonography in Obstetrics and Gynecology. Norwalk, CT, Appleton and Lange, 1991.3. Marret H, Fauconnier A, Chabbert-Buffet N, Cravello L. Clinical practice guidelines on menoorhagia: management of abnormal uterine bleeding before menopause Eur J Obstet Gynecol Reprod Biol 2010;152:133-7.4. De Vries LD, Dijkhuizen FP, Mol BW, Brolmann HA, Moret E, Heintz AP. Comparison of transvaginal sonography, saline infusion sonography, and hysteroscopy in premenopausal women with abnormal uterine bleeding. J Clin Ultrasound 2000;28:217-23.5. Motashaw ND, Dave S. Diagnostic and therapeutic hysteroscopy in the management of abnormal uterine bleeding. J Reprod Med 1990;3:616-20.6. Hoo YC, Mak BS, Hsu C, Wong TS, Ma HK. Postmenopausal uterine bleeding of nonorganic cause. Obstet Gynecol 1985;66:225-8.7. Parulaker SU. Significance of negative hysteroscopic view in abnormal uterine bleeding. J Postgrad Med 1992;38:62-4. 8. Emanuel MH, Verdel MJ, Wamsteker K, Lammes FB. A prospective comparison of transvaginal US and diagnostic hysteroscopy in the evaluation of patients with abnormal uterine bleeding: clinical implications. Am J Obstet Gynecol 1995;172:547-52.9. Cronje HS. Diagnostic hysteroscopy after postmenopausal uterine bleeding. S Afr Med J 1984;66:773-4. 10. Garutti G, Sambruni I, Cellani F, Garzia D, Alleva P, Luerti M. Hysteroscopy and transvaginal ultrasonography in postmenopausal women with uterine bleeding. Int J Gynecol Obstet 1999;65:25-33. 11. Mencaglia L, Vale RF, Perino A, Gilardi G.. Endometriyal carcinoma and its precursors: Early detection and treatment. Int J Gynekol Obstet 1990;31:107-16.12. Hidlebaugh D. A comparison of clinical outcomes and cost of office versus hospital hysteroscopy. J Am Assoc Gynecol Laparosc 1996;4:39-45. 13. Gimpleson R. Office hysteroscopy. Clin Obstet Gynecol 1992;35:270-81. 14. Goldstein SR. Incorporating endovaginal ultrasonography into the overall gynecologic examination. Am J Obstet Gynecol 1990;162:625-32. 15. Crescini C, Artuso A, Repetti F, Reale D, Pezzica E. Hysteroscopic diagnosis in patients with abnormal uterine hemorrhage and previous endometriyal curettage. Minerva Ginecol 1992;44:233-5. 16. Maia H Jr, Barbosa IC, Farias JP, Ladipo OA, Coutinho EM. Evaluation of the endometriyal cavity during menopause. Int J Gynaecol Obstet 1996;52:61-6. 17. Madan SM, Al-Jufairi ZA. Abnormal uterine bleeding. Diagnostic value of hysteroscopy. Saudi Med J 2001;22:153-6. 18. Svirsky R, Smorgick N, Rozowsky U, Sagiv R. Can we rely on blind endometrial biopsy for detection of focal intrauterine pathology? Am J Obstet Gynecol 2008;199:1-3.
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Details

Primary Language English
Subjects Surgery
Journal Section Original Investigation
Authors

Hüseyin Pehlivan This is me

Askın Evren Güler This is me

Bülent Çakmak This is me

Melahat Atasever This is me 0000-0001-8232-4719

Serkan Bodur 0000-0003-4461-9174

Mehmet Ferdi Kıncı 0000-0003-0487-1201

Müfit Cemal Yenen

Publication Date April 1, 2019
Acceptance Date October 23, 2018
Published in Issue Year 2019 Volume: 2 Issue: 1

Cite

EndNote Pehlivan H, Güler AE, Çakmak B, Atasever M, Bodur S, Kıncı MF, Yenen MC (April 1, 2019) The comparison of two endometrial biopsy techniques in detection of endometrial pathologies. Ege Tıp Bilimleri Dergisi 2 1 26–30.

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