Characterization and antifungal applications of azole functional mesoporous and hollow silica nanocomposites

Year 2022, Volume: 5 Issue: (Ek sayı 1), 151 - 156, 30.12.2022

Sedef Kaptan Usul , Ayşe Aslan , Didem Özçimen

https://doi.org/10.46239/ejbcs.1033670

Abstract

In this study, mesoporous (MSN) and hollow (HSS) silica nanoparticles were interacted with vinyltriazole to increase the number of amine groups on the surface. The characterization and antibacterial properties of the prepared nanocomposite structures were investigated. In the characterization of nanocomposites, FTIR and XRD analysis was used to determine the interaction of MSN and HSS with vinyltriazole, the presence of azole groups on the surface, and TGA analysis to examine their thermal properties. SEM analysis was performed to determine the morphology of nanocomposites. The antifungal properties of nanocomposite structures have been proven by the MIC method.

Keywords

mesoporous silica, hollow silica, vinyltriazole

Azol fonksiyonel gözenekli ve içi boş silika nanokompozitlerin karakterizasyonu ve antifungal uygulamaları

Abstract

Bu çalışmada çok gözenekli (MSN) ve tek gözenekli (HSS) silika nanopartiküllerin yüzeyinde, viniltriazol (VTri) monomerinin polimerizasyon reaksiyonu ile amin grupları oluşturulmuştur. Hazırlanan nanokompozit yapıların karakterizasyonu ve antifungal özelliği incelenmiştir. Nanokompozitlerin karakterizasyonunda MSN ve HSS' nın viniltriazol ile etkileşimini, yüzeydeki azol gruplarının varlığını belirlemek için FTIR ve XRD analizi, termal özelliklerini incelemek için TGA analizi yapılmıştır. Nanokompozitlerin morfolojisini belirlemek için SEM analizi yapılmıştır. Nanokompozit yapıların antifungal özellikleri MİK yöntemi ile kanıtlanmıştır.

Keywords

gözenekli silika, tek gözenekli silika, viniltriazol

References

• Aslan A, Elanthikkal S, Bozkurt A. 2019. Chitosan/hollow silica sphere nanocomposites for wound healing application. Journal of Materials Research, 34(2):231-239.
• Aslan A, Soydan AM, Bozkurt A. 2015. Synthesis and characterization of novel multifunctional polymer grafted hollow silica spheres. Journal of Materials Research, 30(16):2408-2416.
• Çelik SÜ, Aslan A, Bozkurt A. 2008. Phosphoric acid-doped poly (1-vinyl-1, 2, 4-triazole) as water-free proton conducting polymer electrolytes. Solid State Ionics, 179(19-20):683-688.
• Derbalah A, Shenashen M, Hamza A, Mohamed A, El Safty S. 2018. Antifungal activity of fabricated mesoporous silica nanoparticles against early blight of tomato. Egyptian journal of basic and applied sciences, 5(2):145-150.
• Durmus Z, Unal B, Toprak MS, Aslan A, Baykal A. 2011. Synthesis and characterization of poly (1-vinyl-1, 2, 4-triazole) (PVTri)–barium hexaferrite nanocomposite. Physica B: Condensed Matter, 406(11):2298-2302.
• Ermakova TG, Shaulina LP, Kuznetsova NP, Volkova LI, Pozdnyakov AS, Prozorova GF. 2012. Sorption of noble metal compounds by cross-linked copolymer of 1-vinyl-1, 2, 4-triazole with acrylic acid. Russian Journal of Applied Chemistry, 85(1):35-40.
• Hachemaoui M, Boukoussa B, Mokhtar A, Mekki A, Beldjilali M, Benaissa M, Hamacha R. 2020. Dyes adsorption, antifungal and antibacterial properties of metal loaded mesoporous silica: Effect of metal and calcination treatment. Materials Chemistry and Physics, 256:123704. Pozdnyakov AS, Ivanova AA, Emel’yanov AI, Bolgova YI, Trofimova OM, Prozorova GF. 2020. Water-soluble stable polymer nanocomposites with AuNPs based on the functional poly (1-vinyl-1, 2, 4-triazole-co-N-vinylpyrrolidone). Journal of Organometallic Chemistry, 922:121352.
• Ribes S, Ruiz-Rico M, Pérez-Esteve É, Fuentes A, Talens P, Martínez-Máñez R, Barat JM. 2017. Eugenol and thymol immobilised on mesoporous silica-based material as an innovative antifungal system: Application in strawberry jam. Food Control, 81:181-188.
• Sattary M, Amini J, Hallaj R. 2020. Antifungal activity of the lemongrass and clove oil encapsulated in mesoporous silica nanoparticles against wheat's take-all disease. Pesticide Biochemistry and Physiology, 170:104696.
• Sinirlioglu D, Muftuoglu AE, Bozkurt A. 2013. 5-(methacrylamido) tetrazole and vinyl triazole based copolymers as novel anhydrous proton conducting membranes. Journal of Polymer Research, 20(9):1-10.
• Son MJ, Lee SW. 2021. Antibacterial toxicity of mesoporous silica nanoparticles with functional decoration of specific organic moieties. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 630:127612.
• Song Y, Zhu P, Wu Y, Tan L, Wei W, Liu S, Chen J. 2019. Epsilon-poly-l-lysine decorated ordered mesoporous silica contributes to the synergistic antifungal effect and enhanced solubility of a lipophilic drug. Materials Science and Engineering: C, 99:231-240.
• Stingaci E, Zveaghinteva M, Pogrebnoi S, Lupascu L, Valica V, Uncu L, Macaev F. 2020. New vinyl-1, 2, 4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. Bioorganic & Medicinal Chemistry Letters, 30(17):127368.
• Zhang R, Cui Y, Cheng M, Guo Y, Wang X, Wang J. 2021. Antifungal activity and mechanism of cinnamon essential oil loaded into mesoporous silica nanoparticles. Industrial Crops and Products, 171:113846.