Angioedema developing in half of the tongue with captopril.

Year 2020, Volume: 2 Issue: 3, 249 - 251, 15.12.2020

Sedat Akkan , Ömür Uyanık

Abstract

Angioedema (AE) is a life-threatening condition that can be seen in hereditary or non-hereditary form, usually manifests in subcutaneous tissue and progressed with edema in the face, lips, tongue, larynx and gastrointestinal system. Captopril is the first generated angiotensin-converting enzyme (ACE) inhibitor. Since the inhibition of ACE and consequently the angiotensin II level in plasma and tissues is reduced and quinine degradation is also inhibited by ACE, the level of bradykinin increases in plasma and tissues. It is thought to that the bradykinin causes edema due to vasodilation and increased vascular permaability. In this case report, we reviewed a 63-year-old patient, who hospitalized in the general surgery ward with the preliminary diagnosis of acute cholecystitis, developed AE after treated with 25 mg captopril for high blood pressure.

Keywords

Angoiedema, ACE inhibitor, Tongue swelling

Thanks

We would like to thank Assoc. Prof. Şeref Kerem Çorbacıoğlu for her contributions in the preparation process of the article.

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