Sclerosing stromal tumor of the ovary with torsion in a postmenopausal woman with elevated serum CA-125 levels

Year 2014, Volume: 19 Issue: 1, 51 - 53, 29.04.2014

Gülşah Balık , Şenol Şentürk , İşık Üstüner , Mehmet Kagıtcı , Cüneyt Yurdakul Emine Seda Güvendağ Güven

Abstract

Sclerosing stromal tumor of the ovary is a subtype of sex cord stromal tumors which is hormonally inactive, benign and extremely rare. Most of the patients are below 30 years of age. These tumors do not cause an increase in tumor markers levels such as CA-125. In here, we present a 66-year-old postmenopausal woman with acute abdomen, elevated CA-125 level and torsion of sclerosing stromal tumor of the ovary.

Keywords

Sclerosing stromal tumor, ovary, CA-125

References

• Chalvardjian A, Scully RE. Sclerosing stromal tumors of the ovary. Cancer 1973; 31: 664-70.
• Stylianidou A, Varras M, Akrivis C, et al. Sclerosing stromal tumor of the ovary: a case report and review of the literature. Eur J Gynaecol Oncol 2001; 22: 300-304. Ho Yuen B, Robertson DI, Clement PB, Mincey EK. Sclerosing stromal tumor of the ovary. Obstet Gynecol 1982; 60: 252-256.
• Quinn MA, Oster AO, Fortune D, Hudson B. Sclerosing stromal tumour of the ovary case report with endocrine studies. Br J Obstet Gynaecol 1981; 88: 555-558.
• Hoskins WJ, Perez CA, Young RC, et al. Principles and Practice of Gynaecologic Oncology, Lippincot Williams and Wilkins, Philadelphia, Pa, USA, 4th edition, 2005. Deavers MT, Malpica A, Liu J, Broaddus R, Silva E. Ovarian sex cord-tumors: an immunohistochemical study including a comparison of calretinin and inhibin. Mod Pathol 2003; 16: 584-590.
• Zhao C, Vinh TN, McManus K, et al. Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cordstromal tumors. Am J Surg Pathol 2009; 33: 354-366. Shaw JA, Dabbs DJ, Geisinger KR. Sclerosing stromal tumor of the ovary: an ultrastructural an immunohistochemical analysis with histogenetic considerations. Ultrastruc Pathol 1992; 16: 363-377.
• Zekioglu O, Ozdemir N, Terek C, Ozsaran A, Dikmen Y. Clinicopathological and immunohistochemical analysis of sclerosing stromal tumours of the ovary. Arch Gynecol Obstet 2010; 282: 671-676.
• Guerriero S, Ajossa S, Caffiero A, Mais V. Relationship between abnormally high levels of plasma CA 125 and resolution of acute pelvic pain in two women with endometrioma. Gynecol Obstet Invest 1995; 40: 61-63.