Inflammatory cell types in Reinke's edema

Year 2017, Volume: 7 Issue: 3, 154 - 156, 28.11.2017

H. Bengü Çobanoğlu , Selçuk Arslan Ümit Çobanoğlu Mehmet İmamoğlu

Abstract

Objective: To evaluate the histopathological
findings in Reinke's edema and correlate them with otorhinolaryngologic
symptoms other than dysphonia.




Methods:
Patients diagnosed with Reinke's edema as the source of dysphonia from
January to December 2016 were included in this retrospective study. The
histopathological findings in Reinke's edema and the correlation with
otorhinolaryngologic symptoms other than dysphonia were evaluated.




Results: A
total of 13 patients (3 females, 10 males) with Reinke's edema all of
whom were smokers underwent surgery. In all of the specimens, the main
histopathological finding was edema in the lamina propria of the vocal
folds. The dominant inflammatory cell type in the stroma was determined
by evaluating the whole microscopic subepithelial zone. The cell types
included plasma cells, lymphocytes, monocytes, and neutrophils.




Conclusion: In
Reinke's edema the main pathologic finding is the collection of
edematous fluid in Reinke's space. As our study was limited by the small
number of cases, we could not find any statistically significant
correlation between the inflammatory cell types and clinical
characteristics of Reinke's edema.

Keywords

Inflammation, Reinke's edema, surgery

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