Kedi ve Köpeklerde Abdominal Cerrahi ve Jinekolojik Operasyonlar Sonrası İntra-Abdominal Adezyon Oluşumu ve Medikal Olarak Önlenmesi

Year 2017, Volume: 14 Issue: 1, 61 - 72, 04.04.2017

İrem Ergin Mürşide Ayşe Demirel

Abstract

İntra-abdominal
adezyon, başta jinekolojik operasyonlar olmak üzere pek çok abdominal cerrahi
girişim sonrası ortaya çıkan; ağrı, intestinal veya üretral tıkanma gibi klinik
semptomlarla kendini gösteren önemli bir komplikasyondur. Abdominal boşlukta
fibrin oluşumu adezyon patofizyolojisinin temelini oluşturmaktadır. İntra-abdominal
adezyonların önlenmesi ile ilgili pek çok pre-klinik ve klinik çalışmalar
yapılmıştır. Bu çalışmalarda hedef, adezyon mekanizmasını iyi anlamak, bu
mekanizmanın bir noktasından girerek zincirin kırılmasını sağlamak ve böylece
adezyon oluşumunu engellemektir. Bu amaçla, farklı etki mekanizmasına sahip pek
çok madde kullanılmaktadır. Bu derlemede, adezyonun oluşum mekanizmasının
ayrıntılı olarak ortaya konması, intra-abdominal adezyon oluşumunu önlemek için
güncel tedavi yöntemlerinin kedi ve köpeklerde abdominal cerrahi ve jinekolojik
operasyonlar sonrası uygulanabilirliğinin araştırmacı ve klinisyenlerle
paylaşılması amaçlanmıştır.

Keywords

İntra-abdominal adezyon, kedi, köpek, operasyon

Intra-Abdominal Adhesion Physiology and Prevention with medical treatment after Gynecologic Operations in Cats and Dogs

Abstract

Intra-abdominal adhesions may occur after
abdominal surgical approach, especially gynecological operations, represent
important clinical symptoms such as pain and intestinal or urethral
obstruction. The formation of fibrin in the abdominal cavity is essential for
adhesion pathophysiology. Several clinical studies were done about prevention
of intra-abdominal adhesions. Aim of these studies was to understand adhesion
mechanism and to prevent adhesion formations. For this purpose, many agents are
used with different mechanisms. In this review, it aimed to reveal in detail
the mechanism of adhesion formation, to share prevention of intra-abdominal
adhesions with current treatment methods especially after abdominal surgery and
gynecological operations in cats and dogs with colleagues and clinicians.

Keywords

Cat, dog, intra-abdominal adhesion, operation

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