Coronavirus Disease 19 and Infertility

Year 2021, , 72 - 77, 30.09.2021

Şeval Çiçek Zeynep Akdemir Selin Çelik Seza Kurukafa İlknur Özkaya İpek Yılmaz Yusuf Aytaç Tohma , Hulusi Zeyneloglu

https://doi.org/10.46969/ezh.942362

Cited By: 1

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes pneumonia, was first detected in Wuhan,
China in December 2019. The cause of the infection is the SARS-CoV-2 virus from the coronavirus family, and since it was
first discovered in 2019, it was named as coronavirus disease 19 (COVID-19). The receptors used by the virus to interact
with the cell are expressed in many organ systems such as type I and type II alveolar epitheli-al cells, enterocytes in
the small intestine, heart, kidneys and testicles. Therefore, COVID-19 affects more than one system. In this review, we
reviewed the relationship between COVID-19 and infertility. The effect of both the virus itself and the pandemic process
on infertility has been emphasized. COVID-19; the effects on the male and female reproductive system, the relationship
between drugs used in treatment with infertility, their relationship with special conditions such as endometriosis and
polycystic ovary syndrome (PCOS), the status of in vitro fertilization (IVF) laboratories during the pandemic period, and
the outcome of the on-going infertility treatments, its psychological dimension and its effect on the psychological status
of infertility patients are mentioned. The fact that the disease is newer and the limited number of studies are limiting
our knowledge. Lack of proven data and long-term results of the studies are the most important difficulties encountered.
Therefore, more studies are needed to increase our knowledge on this subject.

Keywords

Severe acute respiratory syndrome coronavirus 2, COVID-19, Male Infertility, Female Infertility, pregnancy

Koronavirus Hastalığı 19 ve İnfertilite

Abstract

Pnömoniye sebep olan ciddi akut solunum yolu sendromu koronavirus 2 (SARS-CoV-2) ilk olarak 2019 yılının Aralık ayında
Çin’in Wuhan şehrinde saptanmıştır. Enfeksiyonun nedeni koronavirus ailesinden SARS-CoV-2 virüsüdür ve ilk kez 2019
yılında keşfedildiği için koro-navirus hastalığı 19 yani COVID-19 olarak isimledirilmiştir. Virüsün hücreyle etkileşmek için
kullandığı reseptörler tip I ve tip II alveolar epitel hücreleri, ince bağırsaktaki enterositler, kalp, böbrekler ve testisler gibi
pek çok organ sisteminde ifadelenmektedir. Bu nedenle COVID-19 birden fazla sistemi etkilemektedir. Biz bu derlememizde
COVID-19 ve infertilite ilişkisini gözden geçirdik. Hem virüsün kendisinin hem de pandemi sürecinin infertiliteye etkisi
üzerinde durulmuştur. COVID-19’un; erkek ve kadın üreme sistemi üzerine etkilerine, tedavide kullanılan ilaçların infertilite
ile ilişkisine, endometriosis ve polikistik over sendromu (PCOS) gibi özel durumlarla olan ilişkisine, pandemi döneminde
tüp bebek (IVF) laboratuvarlarının durumuna ve halihazırda devam eden infertilite tedavilerinin akıbetine, psikolojik
boyutuna ve infertilite hastalarının psikolojik durumu üzerindeki etkisine değinilmiştir. Hastalığın daha yeni olması ve
yapılan çalışmaların kısıtlılığı bilgilerimizi sınırlandırmaktadır. Kesin kanıtlanmış verilerin bulunmaması ve çalışmaların
uzun dönem sonuçlarının bilinmemesi karşılaşılan en önemli zorluklardır. Bu nedenle bu konu ile ilgili olan bilgilerimizin
artması için daha fazla çalışma yapılması gerekmektedir

Keywords

Ciddi akut solunum yolu sendromu koronavirus 2, COVID-19, erkek infertilitesi, kadın infertilitesi, gebelik

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