ZEYTİN YAPRAĞINDAKİ OLEUROPEİN ve FARMAKOLOJİK ETKİLERİ

Year 2017, Volume: 26 Issue: 1, 89 - 93, 01.03.2017

Ayşe Kübra Karaboğa Arslan , Ebru Öztürk M. Betül Yerer Müberra Koşar

Abstract

Olea europaea L., zeytin, Oleaceae (Zeytingiller)
familyasının bir üyesidir. Zeytin yaprağı, bir sekoiridoit
olan ve antioksidan, antimikrobiyal, antienflamatuvar,
antiaterojenik, antikarsinojenik ve antiviral de dahil bir
çok farmakolojik aktivite göstermesinden sorumlu olan
oleuropein taşımaktadır. Üretici ülke konumunda olan
Türkiye için zeytin, ekonomik ve sosyal açıdan önemli
ürünlerden birisidir. Ülkemizin potansiyeli dikkate alındığında, oleuropein eldesi ve oleuropein ile yapılacak
bilimsel çalışmalarda ülkemiz oldukça önemli bir yere
sahiptir. Yapılmış çalışmalar göz önüne alındığında,
oleuropeinin önemli biyolojik aktivitelere sahip olduğu
ve günümüzde yeni ilaçların geliştirilmesine ışık tutacağı ayrıca eczacılık teknolojisiyle buluşturulup daha
etkili formülasyonların geliştirilip standart farmasötik
formlarda sunulmasının bilim dünyası ve ülke ekonomisine katkı sağlayacağı düşünülmektedir. Bu çalışmada, Oleaceae familyasına dahil olan zeytin yaprağında
yer alan oleuropeinin farmakolojik aktivitelerinin de
içinde bulunduğu çeşitli çalışmalar derlenmiştir. Oleuropein ile yapılan çalışmalar özetlenerek yeni çalışmalara katkı sağlamak amaçlanmıştır

Keywords

Olea europea L., oleuropein, zeytin yaprağı, tıbbi bitki

Oleuropein in Olive Leaf and Its Pharmacologial Effects

Abstract

Olea europaea L. is an olive, a member of the Oleaceae
family. Olive leaves contains oleuropein, a sekoiridoide
which is responsible from many pharmacological activities including antioxidant, antimicrobial, antiinflammatory, antiatherogenic, anticarcinogenic and antiviral
activities. For Turkey, as an olive producer country,
olive is one of the economically and socially important
product. Considering its potential in our country, oleuropein has a very important place and the scientific
studies to be done with oleuropein. Taking into account the studies carried out, it is thought that oleuropein has important biological activities and it will
shed light on the development of new drugs nowadays.
Furthermore it is thought that developing more effective formulations and bringing in pharmaceutical technology and presenting them in standard pharmaceutical forms will contribute to the scientific world and the
country's economy. In this review, various studies including the pharmacological activities of oleuropein in
the olive folium included in the Oleaceae family have
been reviewed. It is aimed to summarize the studies
conducted with oleuropein and contribute to new studies.

Keywords

Olea europea L., oleuropein, olive folium, medicinal plants

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