Research Article
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Enchondromas

Year 2025, EARLY ONLINE, 1 - 7
https://doi.org/10.18621/eurj.1562070

Abstract

Objectives: Enchondromas are benign cartilage tissue tumors composed of mature hyaline cartilage. Most enchondromas are discovered incidentally during radiological examinations. Differentiating between low-grade chondrosarcoma and enchondroma can be difficult both clinically, radiologically, and histologically. Malignant tumors can mimic benign tumors. Therefore, it is crucial to accurately diagnose enchondromas, as the treatments for both tumors are very different. We aimed to contribute to a better understanding of the clinical features and treatment challenges of patients diagnosed with enchondroma.

Methods: Thirty patients who presented to the Department of Orthopedics and Traumatology at Manisa Celal Bayar University Faculty of Medicine between 2010 and 2023 and were diagnosed with enchondroma in hand after surgical treatment were retrospectively evaluated in our study. The patients were classified according to the Tordai and Takigawa classifications.

Results: Nineteen women and 11 men were examined. The lesions were observed in the left hand in 15 patients and in the right hand in 15 patients. The proximal phalanx was the most affected area. Fractures developed in 2 patients during postoperatively, requiring revision surgeries. No wound complications were observed during follow-up, and except for 2 patients who experienced refractures, both clinical and radiological complete healing was observed at the 8-week follow-up.

Conclusions: This study aims to understand better the clinical features and treatment challenges of patients diagnosed with enchondroma. We believe that immobilization for at least 4 weeks or implant application would be appropriate to increase stability in patients with intramedullary involvement of more than 50% in the dominant hand. Enchondromas still present many unknowns, more research is necessary to increase knowledge about these tumors. This study provides important data regarding enchondromas and serves as a foundational step for further research and investigation in this area.

Ethical Statement

After obtaining approval from the Ethics Committee of Mamisa Celal Bayar University (Decision no: 20.478.486/2470 anddate: 05.06.2024), informed consent was obtained from the patients for participation in the study.

References

  • 1. Hakim DN, Pelly T, Kulendran M, Caris JA. Benign tumours of the bone: a review. J Bone Oncol. 2015;4(2):37-41. doi: 10.1016/j.jbo.2015.02.001.
  • 2. Mulligan ME. How to diagno seen chondroma, bone infarct, and chondrosarcoma. Curr Probl Diagn Radiol. 2019;48(3):262-273. doi: 10.1067/j.cpradiol.2018.04.002.
  • 3. Lucas DR, Bridge JA. Chondromas: enchondroma, periosteal chondroma, and enchondromatosis. In: Fletcher CDM, Unni KK, Mertens F, editors. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press; 2002. p.237-240.
  • 4. Romeo S, Hogendorn PC, Dei Tos AP. Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics. Adv Anat Pathol. 2009;16(5):307-315.
  • 5. Schajowicz F, ed., Cartilage-forming tumors. In: Tumors and Tumor-like Lesions of Bone. Springer: Berlin-Heidelberg-New York. 1994.
  • 6. Unni KK, ed., Dahlin's Bone Tumors General Aspects and Data on 11,087 Cases. 5th ed. Lippincott-Raven: Philadelphia. 1996.
  • 7. Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Semin Musculoskelet Radiol. 2000;4(1):59-71. doi: 10.1055/s-2000-6855.
  • 8. Mirra JM. Intramedullary cartilage and chondroid-producing tumors. In: Mirra JM, ed. Bone tumors: clinical, radiologic, and pathologic correlations. Philadelphia, Pa: Lea & Febiger, 1989: p. 439-535.
  • 9. Wessel LE, Christ AB, Athanasian EA. Impact of Patient and Tumor Characteristics on Range of Motion and Recurrence Following Treatment of Enchondromas of the Hand. J Hand Surg Am. 2023;48(5):512.e1-512.e7. doi: 10.1016/j.jhsa.2021.11.027.
  • 10. Sophia A Strike, Mark E Puhaindran. Tumors of the Hand and the Wrist. JBJS Rev. 2020;8(6):e0141. doi: 10.2106/JBJS.RVW.19.00141.
  • 11. Yue KC, Lans J, Castelein RM, et al. Benign Hand Tumors (Part I): Cartilaginous and Bone Tumors. Hand (N Y). 2022;17(2):346-353. doi: 10.1177/1558944720922921.
  • 12. Takigawa, K. Chondroma of the bones of the hand. A review of 110 cases. J. Bone Joint Surg. Am. 1971;53(8):1591-1600.
  • 13. Tordai P, Hoglund M, Lugnegård H. Is the treatment of enchondroma in the hand by simple curettage a rewarding method? J Hand Surg Br. 1990;15(3):331-334. doi: 10.1016/0266-7681_90_90013-t.
  • 14. Potter BK, Freedman BA, Lehman RA Jr, Shawen SB, Kuklo TR, Murphey MD. Solitary epiphyseal enchondromas. J Bone Joint Surg Am. 2005;87(7):1551-1560. doi: 10.2106/JBJS.D.02404.
  • 15. Kramer HD, Valentine MJ, Pettinelli N, Kim J, Kramer RC. Ollier Disease: A Case Report and Review of Treatment Options. Cureus. 2023;15(8):e43815. doi: 10.7759/cureus.43815.
  • 16. Lubahn JD, Bachoura A. Enchondroma of the Hand: Evaluation and Management. J Am Acad Orthop Surg. 2016;24(9):625-633. doi: 10.5435/JAAOS-D-15-00452.
  • 17. Schwartz HS, Zimmerman NB, Simon MA, Wroble RR, Millar EA, Bonfiglio M. The malignant potential of enchondromatosis. J Bone Joint Surg Am. 1987;69(2):269-274.
Year 2025, EARLY ONLINE, 1 - 7
https://doi.org/10.18621/eurj.1562070

Abstract

References

  • 1. Hakim DN, Pelly T, Kulendran M, Caris JA. Benign tumours of the bone: a review. J Bone Oncol. 2015;4(2):37-41. doi: 10.1016/j.jbo.2015.02.001.
  • 2. Mulligan ME. How to diagno seen chondroma, bone infarct, and chondrosarcoma. Curr Probl Diagn Radiol. 2019;48(3):262-273. doi: 10.1067/j.cpradiol.2018.04.002.
  • 3. Lucas DR, Bridge JA. Chondromas: enchondroma, periosteal chondroma, and enchondromatosis. In: Fletcher CDM, Unni KK, Mertens F, editors. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press; 2002. p.237-240.
  • 4. Romeo S, Hogendorn PC, Dei Tos AP. Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics. Adv Anat Pathol. 2009;16(5):307-315.
  • 5. Schajowicz F, ed., Cartilage-forming tumors. In: Tumors and Tumor-like Lesions of Bone. Springer: Berlin-Heidelberg-New York. 1994.
  • 6. Unni KK, ed., Dahlin's Bone Tumors General Aspects and Data on 11,087 Cases. 5th ed. Lippincott-Raven: Philadelphia. 1996.
  • 7. Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Semin Musculoskelet Radiol. 2000;4(1):59-71. doi: 10.1055/s-2000-6855.
  • 8. Mirra JM. Intramedullary cartilage and chondroid-producing tumors. In: Mirra JM, ed. Bone tumors: clinical, radiologic, and pathologic correlations. Philadelphia, Pa: Lea & Febiger, 1989: p. 439-535.
  • 9. Wessel LE, Christ AB, Athanasian EA. Impact of Patient and Tumor Characteristics on Range of Motion and Recurrence Following Treatment of Enchondromas of the Hand. J Hand Surg Am. 2023;48(5):512.e1-512.e7. doi: 10.1016/j.jhsa.2021.11.027.
  • 10. Sophia A Strike, Mark E Puhaindran. Tumors of the Hand and the Wrist. JBJS Rev. 2020;8(6):e0141. doi: 10.2106/JBJS.RVW.19.00141.
  • 11. Yue KC, Lans J, Castelein RM, et al. Benign Hand Tumors (Part I): Cartilaginous and Bone Tumors. Hand (N Y). 2022;17(2):346-353. doi: 10.1177/1558944720922921.
  • 12. Takigawa, K. Chondroma of the bones of the hand. A review of 110 cases. J. Bone Joint Surg. Am. 1971;53(8):1591-1600.
  • 13. Tordai P, Hoglund M, Lugnegård H. Is the treatment of enchondroma in the hand by simple curettage a rewarding method? J Hand Surg Br. 1990;15(3):331-334. doi: 10.1016/0266-7681_90_90013-t.
  • 14. Potter BK, Freedman BA, Lehman RA Jr, Shawen SB, Kuklo TR, Murphey MD. Solitary epiphyseal enchondromas. J Bone Joint Surg Am. 2005;87(7):1551-1560. doi: 10.2106/JBJS.D.02404.
  • 15. Kramer HD, Valentine MJ, Pettinelli N, Kim J, Kramer RC. Ollier Disease: A Case Report and Review of Treatment Options. Cureus. 2023;15(8):e43815. doi: 10.7759/cureus.43815.
  • 16. Lubahn JD, Bachoura A. Enchondroma of the Hand: Evaluation and Management. J Am Acad Orthop Surg. 2016;24(9):625-633. doi: 10.5435/JAAOS-D-15-00452.
  • 17. Schwartz HS, Zimmerman NB, Simon MA, Wroble RR, Millar EA, Bonfiglio M. The malignant potential of enchondromatosis. J Bone Joint Surg Am. 1987;69(2):269-274.
There are 17 citations in total.

Details

Primary Language English
Subjects Hand Surgery, Orthopaedics
Journal Section Original Articles
Authors

Mert Bektaş 0000-0003-0744-8708

Kadir Gem 0000-0002-8607-3491

Mehmet Yalçın 0000-0003-0009-9381

Hakan Koray Tosyalı 0000-0002-1624-1912

Early Pub Date February 12, 2025
Publication Date
Submission Date October 6, 2024
Acceptance Date January 27, 2025
Published in Issue Year 2025 EARLY ONLINE

Cite

AMA Bektaş M, Gem K, Yalçın M, Tosyalı HK. Enchondromas. Eur Res J. Published online February 1, 2025:1-7. doi:10.18621/eurj.1562070

e-ISSN: 2149-3189 


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